Cryo-EM structure of the Carboxyltransferase Domain of Trichoplusia ni Acetyl-Coenzyme A Carboxylase
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 9cv6
Q-score: 0.519
CryoEM structure of METTL6 tRNA SerRS complex in a 1:2:2 stoichiometry
Resolution: 2.42 Å
EM Method: Single-particle
Fitted PDBs: 8p7b
Q-score: 0.615
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo L, Basu S, Kaiser S, Schneider R, Kowalinski E
Nat Struct Mol Biol (2024) 31 pp. 1614-1624 [ DOI: doi:10.1038/s41594-024-01341-3 Pubmed: 38918637 ]
- Mettl6 trna serrs complex in a 1:2:2 stoichiometry (Complex from Homo sapiens)
- Serine--trna ligase, cytoplasmic (58 kDa, Protein from Homo sapiens)
- Trna n(3)-methylcytidine methyltransferase mettl6 (33 kDa, Protein from Homo sapiens)
- Serine trna (27 kDa, RNA from Trichoplusia ni)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Serine trna (27 kDa, RNA from Trichoplusia ni)
- Water (18 Da, Ligand)
CryoEM structure of METTL6 tRNA SerRS complex in a 2:2:2 stoichiometry
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8p7c
Q-score: 0.268
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo L, Basu S, Kaiser S, Schneider R, Kowalinski E
Nat Struct Mol Biol (2024) 31 pp. 1614-1624 [ DOI: doi:10.1038/s41594-024-01341-3 Pubmed: 38918637 ]
- Serine--trna ligase, cytoplasmic (58 kDa, Protein from Homo sapiens)
- Trna n(3)-methylcytidine methyltransferase mettl6 (33 kDa, Protein from Homo sapiens)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Mettl6 trna serrs complex in a 2:2:2 stoichiometry (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Serine trna (27 kDa, RNA from Trichoplusia ni)
- Water (18 Da, Ligand)
CryoEM structure of METTL6 tRNA SerRS complex in a 1:1:2 stoichiometry
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8p7d
Q-score: 0.271
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo L, Basu S, Kaiser S, Schneider R, Kowalinski E
Nat Struct Mol Biol (2024) 31 pp. 1614-1624 [ DOI: doi:10.1038/s41594-024-01341-3 Pubmed: 38918637 ]
- Serine--trna ligase, cytoplasmic (58 kDa, Protein from Homo sapiens)
- Trna n(3)-methylcytidine methyltransferase mettl6 (33 kDa, Protein from Homo sapiens)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Serine trna (27 kDa, RNA from Trichoplusia ni)
- Mettl6 trna serrs complex in a 1:1:2 stoichiometry (Complex from Homo sapiens)
- Water (18 Da, Ligand)
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo L, Basu S, Kaiser S, Schneider R, Kowalinski E
Nat Struct Mol Biol (2024) 31 pp. 1614-1624 [ DOI: doi:10.1038/s41594-024-01341-3 Pubmed: 38918637 ]
- Serrs homodimer (Protein from Homo sapiens)
- Serine trna (RNA from Trichoplusia ni)
- Trna (Complex from Trichoplusia ni)
- Sers (Complex from Homo sapiens)
- Mettl6 trna serrs complex in a 1:2:2 stoichiometry (Complex)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 8va2
Q-score: 0.36
Aher A, Urnavicius L, Xue A, Neselu K, Kapoor TM
Nat Struct Mol Biol (2024) 31 pp. 1124-1133 [ DOI: doi:10.1038/s41594-024-01264-z Pubmed: 38609661 ]
- Tubulin gamma-1 chain (50 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Gamma-tubulin and alpha-tubulin (Complex from Trichoplusia ni)
- Tubulin alpha-1b chain (51 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of the RAF1-HSP90-CDC37 complex in the closed state
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8u1l
Q-score: 0.282
Finci LI, Chakrabarti M, Gulten G, Finney J, Grose C, Fox T, Yang R, Nissley DV, McCormick F, Esposito D, Balius TE, Simanshu DK
Commun Biol (2024) 7 pp. 260-260 [ Pubmed: 38431713 DOI: doi:10.1038/s42003-024-05959-3 ]
- Raf1 & hsp90 co-chaperone cdc37 (Complex from Homo sapiens)
- Heat shock protein 83 (83 kDa, Protein from Trichoplusia ni)
- Hsp90 co-chaperone cdc37, n-terminally processed (44 kDa, Protein from Homo sapiens)
- Raf proto-oncogene serine/threonine-protein kinase (74 kDa, Protein from Homo sapiens)
- Heat shock protein 90 (Complex from Trichoplusia ni)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Complex of raf1-hsp90-cdc37 (Complex)
Cryo-EM structure of the HSP90 dimer (NTD-MD) in the semi-open state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8u1m
Q-score: 0.261
Finci LI, Chakrabarti M, Gulten G, Finney J, Grose C, Fox T, Yang R, Nissley DV, McCormick F, Esposito D, Balius TE, Simanshu DK
Commun Biol (2024) 7 pp. 260-260 [ Pubmed: 38431713 DOI: doi:10.1038/s42003-024-05959-3 ]
- Heat shock protein 83 (83 kDa, Protein from Trichoplusia ni)
- Heat shock protein 90 (166 kDa, Complex from Trichoplusia ni)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of the cross-linked HSP90 dimer (NTD-MD) in the semi-open state
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8u1n
Q-score: 0.333
Finci LI, Chakrabarti M, Gulten G, Finney J, Grose C, Fox T, Yang R, Nissley DV, McCormick F, Esposito D, Balius TE, Simanshu DK
Commun Biol (2024) 7 pp. 260-260 [ Pubmed: 38431713 DOI: doi:10.1038/s42003-024-05959-3 ]
- Heat shock protein 83 (83 kDa, Protein from Trichoplusia ni)
- Heat shock protein 90 (166 kDa, Complex from Trichoplusia ni)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8rbx
Q-score: 0.037
Fianu I, Ochmann M, Walshe JL, Dybkov O, Cruz JN, Urlaub H, Cramer P
Nature (2024) 629 pp. 219-227 [ Pubmed: 38570683 DOI: doi:10.1038/s41586-024-07269-4 ]
- Transcription elongation factor spt5 (121 kDa, Protein from Homo sapiens)
- Integrator-pp2a complex and nelf (Complex from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb11-a (13 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Integrator complex subunit 15 (50 kDa, Protein from Homo sapiens)
- Integrator complex subunit 1 (244 kDa, Protein from Homo sapiens)
- Integrator complex subunit 5 (108 kDa, Protein from Homo sapiens)
- Negative elongation factor a (57 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase subunit (217 kDa, Protein from Sus scrofa)
- Integrator complex subunit 7 (107 kDa, Protein from Homo sapiens)
- Manganese (ii) ion (54 Da, Ligand)
- Integrator complex subunit 2 (134 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Dsif (Complex from Trichoplusia ni)
- Integrator complex subunit 4 (108 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- Rna (5 kDa, RNA from synthetic construct)
- Serine/threonine-protein phosphatase 2a 65 kda regulatory subunit a alpha isoform (65 kDa, Protein from Homo sapiens)
- Unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk-unk (1 kDa, Protein from Homo sapiens)
- Integrator complex subunit 13 (80 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Integrator complex subunit 6 (100 kDa, Protein from Homo sapiens)
- Histone h2a type 1 (14 kDa, Protein from Homo sapiens)
- Non-template dna (45 kDa, DNA from synthetic construct)
- Integrator complex subunit 9 (73 kDa, Protein from Homo sapiens)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Rna and dna (Complex from Sus scrofa)
- Template dna (56 kDa, DNA from synthetic construct)
- Rna polymerase ii subunit d (16 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Sus scrofa)
- Integrator complex subunit 11 (67 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Negative elongation factor c/d (65 kDa, Protein from Homo sapiens)
- Histone h3.3c (15 kDa, Protein from Homo sapiens)
- Unk-unk-unk-unk-unk-unk-unk-unk (698 Da, Protein from Sus scrofa)
- Nucleosome (Complex from Homo sapiens)
- Integrator complex subunit 8 (113 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Sus scrofa)
- Integrator complex subunit 10 (82 kDa, Protein from Homo sapiens)
- Pre-termination complex (1 MDa, Complex)
- Integrator complex subunit 14 (57 kDa, Protein from Homo sapiens)
- Serine/threonine-protein phosphatase 2a catalytic subunit alpha isoform (35 kDa, Protein from Homo sapiens)
- Dss1 (3 kDa, Protein from Trichoplusia ni)
- Dna-directed rna polymerase subunit beta (134 kDa, Protein from Sus scrofa)
- Nelf-b,negative elongation factor b,negative elongation factor b,negative elongation factor b,negative elongation factor b,negative elongation factor b (68 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii (Complex from Homo sapiens)
- Rna polymerase ii subunit k (7 kDa, Protein from Sus scrofa)