Structure of RyR2 (F/A/C/Ca2+ dataset)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6ji0
Q-score: 0.322
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 in complex with fkbp12.6 (Complex from Sus scrofa)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Caffeine (194 Da, Ligand)
Structure of RyR2 (F/apoCaM dataset)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6ji8
Q-score: 0.384
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and apo-calmodulin (Complex from Sus scrofa)
- Ryr2 (564 kDa, Protein from Sus scrofa)
Structure of RyR2 (F/A/C/L-Ca2+/apo-CaM-M dataset)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6jii
Q-score: 0.319
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Ryr2 in complex with fkbp12.6 and apo-calmodulin-mimicking mutant (Complex from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Caffeine (194 Da, Ligand)
Structure of RyR2 (F/A/C/L-Ca2+/Ca2+CaM dataset)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6jiu
Q-score: 0.303
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and ca2+-loaded calmodulin at low ca2+ concentrations (Complex from Sus scrofa)
- Calcium ion (40 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Caffeine (194 Da, Ligand)
Structure of RyR2 (F/A/C/H-Ca2+/Ca2+CaM dataset)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6jiy
Q-score: 0.375
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and ca2+-loaded calmodulin at high ca2+ concentrations (Complex from Sus scrofa)
- Calcium ion (40 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Caffeine (194 Da, Ligand)
Structure of RyR2 (*F/A/C/L-Ca2+ dataset)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6jrr
Q-score: 0.39
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 in complex with fkbp12.6 (Complex from Sus scrofa)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Caffeine (194 Da, Ligand)
Structure of RyR2 (*F/A/C/L-Ca2+/Ca2+-CaM dataset)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6jrs
Q-score: 0.421
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Caffeine (194 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Ryr2 in complex with fkbp12.6 and calmodulin (Complex from Sus scrofa)
Structure of RyR2 (P/L-Ca2+/Ca2+-CaM dataset)
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 6jv2
Q-score: 0.267
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Ryr2 in complex with calmodulin (Complex from Sus scrofa)
- Ryr2 (564 kDa, Protein from Sus scrofa)