The structure of the native cardiac thin filament junction region
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8dd0
Q-score: 0.443
Risi CM, Belknap B, White HD, Dryden K, Pinto JR, Chase PB, Galkin VE
Pnas Nexus (2023) 2 pp. pgac298-pgac298 [ DOI: doi:10.1093/pnasnexus/pgac298 Pubmed: 36712934 ]
- Actin, alpha cardiac muscle 1 (42 kDa, Protein from Sus scrofa)
- Junction region of the native cardiac thin filament (Complex from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Sus scrofa)
- Troponin t2, cardiac type (35 kDa, Protein from Sus scrofa)
ordered protein arrays on the outer mitochondrial membrane of pig sperm mitochondria
Leung MR, Zenezini Chiozzi R, Roelofs MC, Hevler JF, Ravi RT, Maitan P, Zhang M, Henning H, Bromfield EG, Howes SC, Gadella BM, Heck AJR, Zeev-Ben-Mordehai T
PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2110996118 Pubmed: 34737233 ]
Resolution: 35.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7nie
Q-score: 0.032
Leung MR, Zenezini Chiozzi R, Roelofs MC, Hevler JF, Ravi RT, Maitan P, Zhang M, Henning H, Bromfield EG, Howes SC, Gadella BM, Heck AJR, Zeev-Ben-Mordehai T
PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2110996118 Pubmed: 34737233 ]
- Subtomogram average of ordered protein arrays on the axoneme-facing surface of the outer mitochondrial membrane in pig sperm mitochondria (alignment focused on one unit) (Cell from Sus scrofa)
- Voltage-dependent anion-selective channel protein 2 (31 kDa, Protein from Sus scrofa)
- Glycerol kinase (53 kDa, Protein from Sus scrofa)
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 7ko4
Q-score: 0.106
Risi CM, Pepper I, Belknap B, Landim-Vieira M, White HD, Dryden K, Pinto JR, Chase PB, Galkin VE
PNAS (2021) 118 [ Pubmed: 33753506 DOI: doi:10.1073/pnas.2024288118 ]
- Isoform 4 of troponin t, cardiac muscle (23 kDa, Protein from Sus scrofa)
- Troponin i, cardiac muscle (19 kDa, Protein from Sus scrofa)
- Actin, alpha skeletal muscle (41 kDa, Protein from Sus scrofa)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Sus scrofa)
- Cardiac native thin filament (Complex from Sus scrofa)
- Troponin c (18 kDa, Protein from Sus scrofa)
Resolution: 7.8 Å
EM Method: Single-particle
Fitted PDBs: 7ko5
Q-score: 0.113
Risi CM, Pepper I, Belknap B, Landim-Vieira M, White HD, Dryden K, Pinto JR, Chase PB, Galkin VE
PNAS (2021) 118 [ Pubmed: 33753506 DOI: doi:10.1073/pnas.2024288118 ]
- Troponin t, cardiac muscle (23 kDa, Protein from Sus scrofa)
- Troponin i, cardiac muscle (19 kDa, Protein from Sus scrofa)
- Structure of ca2+ bound cardiac native thin filament at pca=5.8 (Complex from Sus scrofa)
- Actin, alpha skeletal muscle (41 kDa, Protein from Sus scrofa)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Sus scrofa)
- Troponin c (18 kDa, Protein from Sus scrofa)
Resolution: 8.3 Å
EM Method: Single-particle
Fitted PDBs: 7ko7
Q-score: 0.112
Risi CM, Pepper I, Belknap B, Landim-Vieira M, White HD, Dryden K, Pinto JR, Chase PB, Galkin VE
PNAS (2021) 118 [ Pubmed: 33753506 DOI: doi:10.1073/pnas.2024288118 ]
- Structure of ca2+ free / ca2+ bound cardiac native thin filament at pca=5.8 mode 1 (Complex from Sus Scofa)
- Troponin t, cardiac muscle (23 kDa, Protein from Sus scrofa)
- Troponin i, cardiac muscle (19 kDa, Protein from Sus scrofa)
- Actin, alpha skeletal muscle (41 kDa, Protein from Sus scrofa)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Sus scrofa)
- Troponin c (18 kDa, Protein from Sus scrofa)
Resolution: 8.1 Å
EM Method: Single-particle
Fitted PDBs: 7kon
Q-score: 0.112
Risi CM, Pepper I, Belknap B, Landim-Vieira M, White HD, Dryden K, Pinto JR, Chase PB, Galkin VE
PNAS (2021) 118 [ Pubmed: 33753506 DOI: doi:10.1073/pnas.2024288118 ]
- Structure of ca2+ free / ca2+ bound cardiac native thin filament at pca=5.8 mode 2 (Complex from Sus scrofa)
- Troponin t, cardiac muscle (23 kDa, Protein from Sus scrofa)
- Troponin i, cardiac muscle (19 kDa, Protein from Sus scrofa)
- Actin, alpha skeletal muscle (41 kDa, Protein from Sus scrofa)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Sus scrofa)
- Troponin c (18 kDa, Protein from Sus scrofa)
Resolution: 7.8 Å
EM Method: Single-particle
Fitted PDBs: 7kor
Q-score: 0.113
Risi CM, Pepper I, Belknap B, Landim-Vieira M, White HD, Dryden K, Pinto JR, Chase PB, Galkin VE
PNAS (2021) 118 [ Pubmed: 33753506 DOI: doi:10.1073/pnas.2024288118 ]
- Troponin t, cardiac muscle (23 kDa, Protein from Sus scrofa)
- Troponin i, cardiac muscle (19 kDa, Protein from Sus scrofa)
- Actin, alpha skeletal muscle (41 kDa, Protein from Sus scrofa)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Sus scrofa)
- Native cardiac thin filament (Complex from Sus scrofa)
- Troponin c (18 kDa, Protein from Sus scrofa)
Structure of RyR2 (Ca2+ alone dataset)
Resolution: 6.1 Å
EM Method: Single-particle
Fitted PDBs: 6jg3
Q-score: 0.184
Chi X, Gong D, Ren K, Zhou G, Huang G, Lei J, Zhou Q, Yan N
PNAS (2019) 116 pp. 25575-25582 [ Pubmed: 31792195 DOI: doi:10.1073/pnas.1914451116 ]
- Homotetramer (Complex from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Ryanodine receptor 2 (564 kDa, Protein from Sus scrofa)
Structure of RyR2 (F/P/Ca2+ dataset)
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 6jgz
Q-score: 0.249
Chi X, Gong D, Ren K, Zhou G, Huang G, Lei J, Zhou Q, Yan N
PNAS (2019) 116 pp. 25575-25582 [ Pubmed: 31792195 DOI: doi:10.1073/pnas.1914451116 ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Ryr2 in complex with fkbp12.6 (Complex from Sus scrofa)
- Zinc ion (65 Da, Ligand)