The structure of the native cardiac thin filament junction region
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8dd0
Q-score: 0.443
Risi CM, Belknap B, White HD, Dryden K, Pinto JR, Chase PB, Galkin VE
Pnas Nexus (2023) 2 pp. pgac298-pgac298 [ DOI: doi:10.1093/pnasnexus/pgac298 Pubmed: 36712934 ]
- Troponin t2, cardiac type (35 kDa, Protein from Sus scrofa)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Actin, alpha cardiac muscle 1 (42 kDa, Protein from Sus scrofa)
- Junction region of the native cardiac thin filament (Complex from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Structure of RyR2 (Ca2+ alone dataset)
Resolution: 6.1 Å
EM Method: Single-particle
Fitted PDBs: 6jg3
Q-score: 0.184
Chi X, Gong D, Ren K, Zhou G, Huang G, Lei J, Zhou Q, Yan N
PNAS (2019) 116 pp. 25575-25582 [ DOI: doi:10.1073/pnas.1914451116 Pubmed: 31792195 ]
- Ryanodine receptor 2 (564 kDa, Protein from Sus scrofa)
- Homotetramer (Complex from Sus scrofa)
- Zinc ion (65 Da, Ligand)
Structure of RyR2 (F/P/Ca2+ dataset)
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 6jgz
Q-score: 0.249
Chi X, Gong D, Ren K, Zhou G, Huang G, Lei J, Zhou Q, Yan N
PNAS (2019) 116 pp. 25575-25582 [ DOI: doi:10.1073/pnas.1914451116 Pubmed: 31792195 ]
- Ryr2 in complex with fkbp12.6 (Complex from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
Structure of RyR2 (F/A/Ca2+ dataset)
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 6jh6
Q-score: 0.222
Chi X, Gong D, Ren K, Zhou G, Huang G, Lei J, Zhou Q, Yan N
PNAS (2019) 116 pp. 25575-25582 [ DOI: doi:10.1073/pnas.1914451116 Pubmed: 31792195 ]
- Zinc ion (65 Da, Ligand)
- Ryr2 in complex with fkbp12.6 (Complex from Sus scrofa)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
Structure of RyR2 (F/C/Ca2+ dataset)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6jhn
Q-score: 0.252
Chi X, Gong D, Ren K, Zhou G, Huang G, Lei J, Zhou Q, Yan N
PNAS (2019) 116 pp. 25575-25582 [ DOI: doi:10.1073/pnas.1914451116 Pubmed: 31792195 ]
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Ryr2 in complex with fkbp12.6 (Complex from Sus scrofa)
- Caffeine (194 Da, Ligand)
CryoEM Density of Acetylated Microtubules
Resolution: 3.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 6o2q
Q-score: 0.428
Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso DB, Lohr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E
PNAS (2019) 116 pp. 10366-10371 [ DOI: doi:10.1073/pnas.1900441116 Pubmed: 31072936 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Acetylated microtubule (Tissue from Sus scrofa)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 6o2r
Q-score: 0.461
Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso DB, Lohr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E
PNAS (2019) 116 pp. 10366-10371 [ DOI: doi:10.1073/pnas.1900441116 Pubmed: 31072936 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Deacetylated microtubule (Tissue from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
Resolution: 4.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 6o2s
Q-score: 0.275
Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso DB, Lohr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E
PNAS (2019) 116 pp. 10366-10371 [ DOI: doi:10.1073/pnas.1900441116 Pubmed: 31072936 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Deacetylated microtubule (Tissue from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
Resolution: 4.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 6o2t
Q-score: 0.252
Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso DB, Lohr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E
PNAS (2019) 116 pp. 10366-10371 [ DOI: doi:10.1073/pnas.1900441116 Pubmed: 31072936 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Acetylated microtubule (Tissue from Sus scrofa)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
Undecorated GMPCPP microtubule
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 6dpu
Q-score: 0.494
Zhang R, LaFrance B, Nogales E
PNAS (2018) 115 pp. E6191-E6200 [ DOI: doi:10.1073/pnas.1802637115 Pubmed: 29915050 ]
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Microtubule stabilized by gmpcpp (Complex from Sus scrofa)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)