Leung MR, Sun C, Zeng J, Anderson JR, Niu Q, Huang W, Noteborn WEM, Brown A, Zeev-Ben-Mordehai T, Zhang R
Nature (2025) [ Pubmed: 39743588 DOI: doi:10.1038/s41586-024-08337-5 ]
Leung MR, Sun C, Zeng J, Anderson JR, Niu Q, Huang W, Noteborn WEM, Brown A, Zeev-Ben-Mordehai T, Zhang R
Nature (2025) [ Pubmed: 39743588 DOI: doi:10.1038/s41586-024-08337-5 ]
Leung MR, Sun C, Zeng J, Anderson JR, Niu Q, Huang W, Noteborn WEM, Brown A, Zeev-Ben-Mordehai T, Zhang R
Nature (2025) [ Pubmed: 39743588 DOI: doi:10.1038/s41586-024-08337-5 ]
Leung MR, Sun C, Zeng J, Anderson JR, Niu Q, Huang W, Noteborn WEM, Brown A, Zeev-Ben-Mordehai T, Zhang R
Nature (2025) [ Pubmed: 39743588 DOI: doi:10.1038/s41586-024-08337-5 ]
Microtubule-associated kinesin-1 tail complex bound to AMPPNP, single-headed state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rhb
Q-score: 0.064
Atherton J, Chegkazi MS, Peirano E, Pozzer LS, Foran T, Steiner RA
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.11.622991 ]
- 13pf microtubule bound to kif5bmoneiak in the presence of amppnp (246 MDa, Complex)
- Kinesin-1 heavy chain (Complex from Homo sapiens)
- 13pf microtubule (Complex from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Taxol (853 Da, Ligand)
- Kinesin-1 heavy chain (109 kDa, Protein from Homo sapiens)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
Microtubule-associated kinesin-1 tail complex bound to AMPPNP, two-headed state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rhh
Q-score: 0.462
Atherton J, Chegkazi MS, Peirano E, Pozzer LS, Foran T, Steiner RA
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.11.622991 ]
- Kinesin-1 heavy chain (Complex from Homo sapiens)
- 13pf microtubule bound to kif5bmoneiak in the presence of amppnp (two-headed state) (246 MDa, Complex)
- 13pf microtubule (Complex from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Taxol (853 Da, Ligand)
- Kinesin-1 heavy chain (109 kDa, Protein from Homo sapiens)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
Microtubule-associated kinesin-1 tail complex bound to ADP, single-headed state
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8rik
Q-score: 0.525
Atherton J, Chegkazi MS, Peirano E, Pozzer LS, Foran T, Steiner RA
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.11.622991 ]
- Kinesin-1 heavy chain (Complex from Homo sapiens)
- 13pf microtubule (Complex from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 13pf microtubule bound to kif5bmoneiak in the presence of adp (246 MDa, Complex)
- Taxol (853 Da, Ligand)
- Kinesin-1 heavy chain (109 kDa, Protein from Homo sapiens)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Microtubule-associated kinesin-1 tail complex bound to ADP, two-headed state
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8riz
Q-score: 0.421
Atherton J, Chegkazi MS, Peirano E, Pozzer LS, Foran T, Steiner RA
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.11.622991 ]
- 13pf microtubule bound to kif5bmoneiak in the presence of adp (two-headed state) (246 MDa, Complex)
- Kinesin-1 heavy chain (Complex from Homo sapiens)
- 13pf microtubule (Complex from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Taxol (853 Da, Ligand)
- Kinesin-1 heavy chain (109 kDa, Protein from Homo sapiens)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)