Microtubule-associated kinesin-1 tail complex bound to AMPPNP, single-headed state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rhb
Q-score: 0.064
Atherton J, Chegkazi MS, Peirano E, Pozzer LS, Foran T, Steiner RA
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.11.622991 ]
- 13pf microtubule bound to kif5bmoneiak in the presence of amppnp (246 MDa, Complex)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- 13pf microtubule (Complex from Sus scrofa)
- Kinesin-1 heavy chain (109 kDa, Protein from Homo sapiens)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin-1 heavy chain (Complex from Homo sapiens)
- Taxol (853 Da, Ligand)
Microtubule-associated kinesin-1 tail complex bound to AMPPNP, two-headed state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8rhh
Q-score: 0.462
Atherton J, Chegkazi MS, Peirano E, Pozzer LS, Foran T, Steiner RA
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.11.622991 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- 13pf microtubule bound to kif5bmoneiak in the presence of amppnp (two-headed state) (246 MDa, Complex)
- 13pf microtubule (Complex from Sus scrofa)
- Kinesin-1 heavy chain (109 kDa, Protein from Homo sapiens)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin-1 heavy chain (Complex from Homo sapiens)
- Taxol (853 Da, Ligand)
Microtubule-associated kinesin-1 tail complex bound to ADP, single-headed state
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8rik
Q-score: 0.525
Atherton J, Chegkazi MS, Peirano E, Pozzer LS, Foran T, Steiner RA
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.11.622991 ]
- Kinesin-1 heavy chain (109 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 13pf microtubule bound to kif5bmoneiak in the presence of adp (246 MDa, Complex)
- Taxol (853 Da, Ligand)
- Kinesin-1 heavy chain (Complex from Homo sapiens)
- 13pf microtubule (Complex from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Microtubule-associated kinesin-1 tail complex bound to ADP, two-headed state
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8riz
Q-score: 0.421
Atherton J, Chegkazi MS, Peirano E, Pozzer LS, Foran T, Steiner RA
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.11.622991 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- 13pf microtubule (Complex from Sus scrofa)
- Kinesin-1 heavy chain (109 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 13pf microtubule bound to kif5bmoneiak in the presence of adp (two-headed state) (246 MDa, Complex)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin-1 heavy chain (Complex from Homo sapiens)
- Taxol (853 Da, Ligand)
Microtubule-associated Kif5B IAK tail mutant bound to ADP
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9gnq
Q-score: 0.54
Atherton J, Chegkazi MS, Peirano E, Pozzer LS, Foran T, Steiner RA
bioRxiv (2024) [ DOI: doi:10.1101/2024.11.11.622991 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Sus scrofa)
- Alpha-tubulin (Complex from Sus scrofa)
- Kinesin-1 heavy chain (44 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Tubulin alpha-1b chain (50 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kif5bmonexxx bound with adp (Complex from Homo sapiens)
- Taxol (853 Da, Ligand)
- 13pf microtubule bound to kif5bmonexxx in the presence of adp (246 MDa, Complex)
- Beta tubulin (Complex from Sus scrofa)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8v3q
Q-score: 0.542
Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
Nature (2024) 631 pp. 905-912 [ DOI: doi:10.1038/s41586-024-07699-0 Pubmed: 39020174 ]
- Zinc ion (65 Da, Ligand)
- Ccp5 in complex with beta tubulin tail (Complex)
- Glutamic acid (147 Da, Ligand)
- Cytosolic carboxypeptidase-like protein 5 (68 kDa, Protein from Homo sapiens)
- Beta tubulin tail (827 Da, Protein from Sus scrofa)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8v3r
Q-score: 0.49
Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
Nature (2024) 631 pp. 905-912 [ Pubmed: 39020174 DOI: doi:10.1038/s41586-024-07699-0 ]
- Beta tubulin tail (487 Da, Protein from Sus scrofa)
- Cytosolic carboxypeptidase-like protein 5 (68 kDa, Protein from Homo sapiens)
- Ccp5 in complex with beta tubulin tail (Complex)
- Zinc ion (65 Da, Ligand)
- Glutamic acid (147 Da, Ligand)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8v3s
Q-score: 0.456
Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
Nature (2024) 631 pp. 905-912 [ Pubmed: 39020174 DOI: doi:10.1038/s41586-024-07699-0 ]
- Beta tubulin tail (487 Da, Protein from Sus scrofa)
- Cytosolic carboxypeptidase-like protein 5 (68 kDa, Protein from Homo sapiens)
- Ccp5 in complex with beta tubulin tail (Complex)
- Zinc ion (65 Da, Ligand)
- Glutamic acid (147 Da, Ligand)
Cytoplasmic dynein-1 A1/A2 motor domains bound to LIS1
Resolution: 5.5 Å
EM Method: Single-particle
Fitted PDBs: 8pqz
Q-score: 0.284
Singh K, Lau CK, Manigrasso G, Gama JB, Gassmann R, Carter AP
Science (2024) 383 pp. eadk8544-eadk8544 [ Pubmed: 38547289 DOI: doi:10.1126/science.adk8544 ]
- Magnesium ion (24 Da, Ligand)
- Dynactin subunit 1 (142 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein 1 heavy chain 1 (533 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Cytoplasmic dynein 1 intermediate chain 2 (68 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cytoplasmic dynein-a1/a2 motor domains bound to lis1 (Complex from Homo sapiens)
- Platelet-activating factor acetylhydrolase ib subunit beta (46 kDa, Protein from Homo sapiens)
Cytoplasmic dynein-A heavy chain bound to dynactin-p150glued and IC-LC tower
Resolution: 9.4 Å
EM Method: Single-particle
Fitted PDBs: 8pr0
Q-score: 0.169
Singh K, Lau CK, Manigrasso G, Gama JB, Gassmann R, Carter AP
Science (2024) 383 pp. eadk8544-eadk8544 [ Pubmed: 38547289 DOI: doi:10.1126/science.adk8544 ]
- Dynactin subunit 1 (142 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein-a heavy chain bound to dynactin p150 and ic-lc tower (Complex from Homo sapiens)
- Cytoplasmic dynein 1 light intermediate chain 2 (54 kDa, Protein from Homo sapiens)
- Cytoplasmic dynein 1 intermediate chain 2 (68 kDa, Protein from Homo sapiens)
- Dynein light chain tctex-type 1 (12 kDa, Protein from Homo sapiens)
- Cytoplasmic dynein 1 heavy chain 1 (533 kDa, Protein from Homo sapiens)
- Dynein light chain 1, cytoplasmic (10 kDa, Protein from Homo sapiens)