HIV-1 BG505 Env SOSIP in complex with bovine Fab Bess4 and non-human primate Fab RM20A3
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8tq1
Q-score: 0.512
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Sewall LM, Joyce C, Song G, Porter K, Landais E, Andrabi R, Wilson IA, Ward AB, Mwangi W, Smider VV, Burton DR, Sok D
PLoS Pathog (2024) 20 pp. e1012042-e1012042 [ Pubmed: 39250525 DOI: doi:10.1371/journal.ppat.1012042 ]
- Nhp rm20a3 fab heavy chain (13 kDa, Protein from Macaca mulatta)
- Hiv-1 bg505 sosip env in complex with bovine bess4 fab and nhp rm20a3 fab (Complex from Human immunodeficiency virus 1)
- Bovine bess4 fab heavy chain (17 kDa, Protein from Bos taurus)
- Nhp rm20a3 fab light chain (13 kDa, Protein from Macaca mulatta)
- Transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hiv-1 envelope glycoprotein bg505 sosip.664 gp120 (57 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 7t2p
Q-score: 0.422
Zhao F, Berndsen ZT, Pedreno-Lopez N, Burns A, Allen JD, Barman S, Lee WH, Chakraborty S, Gnanakaran S, Sewall LM, Ozorowski G, Limbo O, Song G, Yong P, Callaghan S, Coppola J, Weisgrau KL, Lifson JD, Nedellec R, Voigt TB, Laurino F, Louw J, Rosen BC, Ricciardi M, Crispin M, Desrosiers RC, Rakasz EG, Watkins DI, Andrabi R, Ward AB, Burton DR, Sok D
Nat Commun (2022) 13 pp. 5236-5236 [ Pubmed: 36068229 DOI: doi:10.1038/s41467-022-32783-2 ]
- K11 fab light chain (25 kDa, Protein from Macaca mulatta)
- K11 fab heavy chain (53 kDa, Protein from Macaca mulatta)
- Sivmac239.k180s sosip trimer in complex with 3 copies of k11 fab (Complex from Simian immunodeficiency virus)
- Envelope glycoprotein gp120 (60 kDa, Protein from Simian immunodeficiency virus)
- Envelope glycoprotein gp41 (18 kDa, Protein from Simian immunodeficiency virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SIVmac239.K180S SOSIP in complex with FZ019.2 Fab
Zhao F, Berndsen ZT, Pedreno-Lopez N, Burns A, Allen JD, Barman S, Lee WH, Chakraborty S, Gnanakaran S, Sewall LM, Ozorowski G, Limbo O, Song G, Yong P, Callaghan S, Coppola J, Weisgrau KL, Lifson JD, Nedellec R, Voigt TB, Laurino F, Louw J, Rosen BC, Ricciardi M, Crispin M, Desrosiers RC, Rakasz EG, Watkins DI, Andrabi R, Ward AB, Burton DR, Sok D
Nat Commun (2022) 13 pp. 5236-5236 [ DOI: doi:10.1038/s41467-022-32783-2 Pubmed: 36068229 ]
- Sivmac239.k180s sosip (Macromolecule from Simian immunodeficiency virus)
- Fz019.2 fab heavy chain (Macromolecule from Macaca mulatta)
- Sivmac239.k180s sosip trimer in complex with 1 copy of fz019.2 fab (Complex from Simian immunodeficiency virus)
- Fz019.2 fab light chain (Macromolecule from Macaca mulatta)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7t4g
Q-score: 0.406
Zhao F, Berndsen ZT, Pedreno-Lopez N, Burns A, Allen JD, Barman S, Lee WH, Chakraborty S, Gnanakaran S, Sewall LM, Ozorowski G, Limbo O, Song G, Yong P, Callaghan S, Coppola J, Weisgrau KL, Lifson JD, Nedellec R, Voigt TB, Laurino F, Louw J, Rosen BC, Ricciardi M, Crispin M, Desrosiers RC, Rakasz EG, Watkins DI, Andrabi R, Ward AB, Burton DR, Sok D
Nat Commun (2022) 13 pp. 5236-5236 [ Pubmed: 36068229 DOI: doi:10.1038/s41467-022-32783-2 ]
- K11 igg heavy chain (53 kDa, Protein from Macaca mulatta)
- Sivmac239.k180s sosip trimer in complex with 3 copies of k11 igg (Complex from Simian immunodeficiency virus)
- Envelope glycoprotein gp120 (60 kDa, Protein from Simian immunodeficiency virus)
- Envelope glycoprotein gp41 (18 kDa, Protein from Simian immunodeficiency virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- K11 igg light chain (25 kDa, Protein from Macaca mulatta)
SARS-CoV-2 6P Mut7 in complex with K398.25 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-1 in complex with K398.25 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-2 6P Mut7 in complex with K398.16 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ DOI: doi:10.1126/scitranslmed.abl9605 Pubmed: 35947674 ]
SARS-CoV-2 6P Mut7 in complex with K398.16 Fab (3 bound)
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-1 in complex with K398.16 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]
SARS-CoV-2 6P Mut7 in complex with K288.2 Fab
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, Huang D, Anzanello F, Ricketts J, Parren M, Garcia E, Ferguson M, Rinaldi W, Rawlings SA, Nemazee D, Smith DM, Briney B, Safonova Y, Rogers TF, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Irvine DJ, Ward AB, Wilson IA, Burton DR, Andrabi R
Sci Transl Med (2022) 14 pp. eabl9605-eabl9605 [ Pubmed: 35947674 DOI: doi:10.1126/scitranslmed.abl9605 ]