Influenza polymerase A/H7N9-4M (ENDO(R) | Core1)
Arragain B, Krischuns T, Pelosse M, Drncova P, Blackledge M, Naffakh N, Cusack S
Nat Commun (2024) 15 pp. 6910-6910 [ DOI: doi:10.1038/s41467-024-51007-3 Pubmed: 39160148 ]
- Magnesium ion (24 Da, Ligand)
- Heterotrimeric complex (Complex from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Polymerase acidic protein (82 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Polymerase basic protein 2 (89 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
Influenza polymerase A/H7N9-4M (ENDO(R) | Core2)
Arragain B, Krischuns T, Pelosse M, Drncova P, Blackledge M, Naffakh N, Cusack S
Nat Commun (2024) 15 pp. 6910-6910 [ DOI: doi:10.1038/s41467-024-51007-3 Pubmed: 39160148 ]
- Magnesium ion (24 Da, Ligand)
- Heterotrimeric complex (Complex from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Water (18 Da, Ligand)
- Polymerase acidic protein (82 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Polymerase basic protein 2 (89 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8rmr
Q-score: 0.326
Arragain B, Krischuns T, Pelosse M, Drncova P, Blackledge M, Naffakh N, Cusack S
Nat Commun (2024) 15 pp. 6910-6910 [ DOI: doi:10.1038/s41467-024-51007-3 Pubmed: 39160148 ]
- Magnesium ion (24 Da, Ligand)
- Polymerase acidic protein (82 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Asymmetric dimer composed of one flupola/h7n9-4m replicase and one flupola/h7n9-4m encapsidase, bridged by human anp32a (Complex from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Polymerase basic protein 2 (89 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Acidic leucine-rich nuclear phosphoprotein 32 family member a (31 kDa, Protein from Homo sapiens)
Arragain B, Krischuns T, Pelosse M, Drncova P, Blackledge M, Naffakh N, Cusack S
Nat Commun (2024) 15 pp. 6910-6910 [ DOI: doi:10.1038/s41467-024-51007-3 Pubmed: 39160148 ]
- Magnesium ion (24 Da, Ligand)
- Heterotrimeric complex (Complex from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Polymerase acidic protein (82 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Polymerase basic protein 2 (89 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
- Rna-directed rna polymerase catalytic subunit (86 kDa, Protein from Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
Arragain B, Krischuns T, Pelosse M, Drncova P, Blackledge M, Naffakh N, Cusack S
Nat Commun (2024) 15 pp. 6910-6910 [ DOI: doi:10.1038/s41467-024-51007-3 Pubmed: 39160148 ]
- Magnesium ion (24 Da, Ligand)
- Polymerase basic protein 2 (90 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Heterotrimeric complex from a pseudo-symmetrical dimer (Complex from Influenza B virus (B/Memphis/13/2003))
- Rna-directed rna polymerase catalytic subunit (84 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Polymerase acidic protein (83 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
Arragain B, Krischuns T, Pelosse M, Drncova P, Blackledge M, Naffakh N, Cusack S
Nat Commun (2024) 15 pp. 6910-6910 [ DOI: doi:10.1038/s41467-024-51007-3 Pubmed: 39160148 ]
- Magnesium ion (24 Da, Ligand)
- Polymerase basic protein 2 (90 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Heterotrimeric complex from a pseudo-symmetrical dimer (Complex from Influenza B virus (B/Memphis/13/2003))
- Rna-directed rna polymerase catalytic subunit (84 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Polymerase acidic protein (83 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
Arragain B, Krischuns T, Pelosse M, Drncova P, Blackledge M, Naffakh N, Cusack S
Nat Commun (2024) 15 pp. 6910-6910 [ DOI: doi:10.1038/s41467-024-51007-3 Pubmed: 39160148 ]
- Magnesium ion (24 Da, Ligand)
- Polymerase basic protein 2 (90 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Heterotrimeric complex from a pseudo-symmetrical dimer (Complex from Influenza B virus (B/Memphis/13/2003))
- Rna-directed rna polymerase catalytic subunit (84 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Polymerase acidic protein (83 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
Arragain B, Krischuns T, Pelosse M, Drncova P, Blackledge M, Naffakh N, Cusack S
Nat Commun (2024) 15 pp. 6910-6910 [ DOI: doi:10.1038/s41467-024-51007-3 Pubmed: 39160148 ]
- Magnesium ion (24 Da, Ligand)
- Polymerase basic protein 2 (90 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Heterotrimeric complex from a pseudo-symmetrical dimer (Complex from Influenza B virus (B/Memphis/13/2003))
- Rna-directed rna polymerase catalytic subunit (84 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Polymerase acidic protein (83 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
Influenza B polymerase pseudo-symmetrical apo-dimer (FluPol(E)|FluPol(S))
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8rn8
Q-score: 0.503
Arragain B, Krischuns T, Pelosse M, Drncova P, Blackledge M, Naffakh N, Cusack S
Nat Commun (2024) 15 pp. 6910-6910 [ Pubmed: 39160148 DOI: doi:10.1038/s41467-024-51007-3 ]
- Magnesium ion (24 Da, Ligand)
- Pseudo-symmetrical dimer of two heterotrimers (Complex from Influenza B virus (B/Memphis/13/2003))
- Rna-directed rna polymerase catalytic subunit (84 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Polymerase acidic protein (83 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
- Polymerase basic protein 2 (90 kDa, Protein from Influenza B virus (B/Memphis/13/2003))
5'vRNA-bound Hantaan virus polymerase in monomeric active state
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8qh3
Q-score: 0.563
Durieux Trouilleton Q, Housset D, Tarillon P, Arragain B, Malet H
Nat Commun (2024) 15 pp. 2256-2256 [ DOI: doi:10.1038/s41467-024-46601-4 Pubmed: 38480734 ]
- Magnesium ion (24 Da, Ligand)
- Rna (5'-r(p*ap*gp*up*ap*gp*up*ap*gp*ap*cp*a)-3') (8 kDa, RNA from Hantaan virus 76-118)
- Hantaan virus polymerase (250 kDa, Complex)
- Rna-directed rna polymerase l (249 kDa, Protein from Hantaan virus 76-118)
- Rna (5'-r(p*ap*gp*up*ap*gp*up*ap*gp*ap*cp*a)-3') (Complex from Hantaan virus 76-118)
- Rna-directed rna polymerase l (Complex from Hantaan virus 76-118)