50S ribosomal subunit from Staphylococcus aureus (Strain ATCC43300)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7ttu
Q-score: 0.447
Perlaza-Jimenez L, Tan KS, Piper SJ, Johnson RM, Bamert RS, Stubenrauch CJ, Wright A, Lupton D, Lithgow T, Belousoff MJ
Microbiol Spectr (2022) 10 pp. e0058322-e0058322 [ Pubmed: 35736238 DOI: doi:10.1128/spectrum.00583-22 ]
- 50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l16 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal subunit from staphylococcus aureus (Complex from Staphylococcus aureus)
- 50s ribosomal protein l2 (30 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l29 (8 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l27 (10 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus)
- 23s rrna (946 kDa, RNA from Staphylococcus aureus)
- 5s rrna (36 kDa, RNA from Staphylococcus aureus)
- 50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l18 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l35 (7 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l25 (23 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l32 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l19 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l33 (5 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l34 (5 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7ttw
Q-score: 0.598
Perlaza-Jimenez L, Tan KS, Piper SJ, Johnson RM, Bamert RS, Stubenrauch CJ, Wright A, Lupton D, Lithgow T, Belousoff MJ
Microbiol Spectr (2022) 10 pp. e0058322-e0058322 [ DOI: doi:10.1128/spectrum.00583-22 Pubmed: 35736238 ]
- 50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l18 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal subunit from staphylococcus aureus - double mutation in ul3 leading to linezolid resistance (Complex from Staphylococcus aureus)
- 50s ribosomal protein l2 (30 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l25 (23 kDa, Protein from Staphylococcus aureus)
- 23s rrna (946 kDa, RNA from Staphylococcus aureus)
- 50s ribosomal protein l34 (5 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus)
- 5s rrna (36 kDa, RNA from Staphylococcus aureus)
- 50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l27 (10 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l16 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l29 (8 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l33 (5 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l32 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l19 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l35 (7 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus)
DpK2 bacteriophage tail spike depolymerase
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7lzj
Q-score: 0.632
Dunstan RA, Bamert RS, Belousoff MJ, Short FL, Barlow CK, Pickard DJ, Wilksch JJ, Schittenhelm RB, Strugnell RA, Dougan G, Lithgow T
Microbiol Spectr (2021) 9 pp. e0102321-e0102321 [ Pubmed: 34431721 DOI: doi:10.1128/Spectrum.01023-21 ]
- Dpk2 depolymerase tail spike complex (Complex from Bacteriophage sp.)
- Depolymerase (98 kDa, Protein from Klebsiella phage GH-K3)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6ddd
Q-score: 0.554
Belousoff MJ, Venugopal H, Wright A, Seoner S, Stuart I, Stubenrauch C, Bamert RS, Lupton DW, Lithgow T
Chem Med Chem (2019) 14 pp. 527-531 [ DOI: doi:10.1002/cmdc.201900042 Pubmed: 30667174 ]
- 50s ribosomal protein l16 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal subunit from mrsa in complex with oxazolidinone lzd-5 (Complex from Staphylococcus aureus)
- 50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l27 (9 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l34 (6 kDa, Protein from Staphylococcus aureus)
- 5s rrna (36 kDa, RNA from Staphylococcus aureus)
- 50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l18 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l35 (7 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l25 (23 kDa, Protein from Staphylococcus aureus)
- 2,2-dichloro-n-({(5s)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide (406 Da, Ligand)
- 50s ribosomal protein l32 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l19 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l29 (8 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l33 (5 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus)
- 23s rrna (946 kDa, RNA from Staphylococcus aureus)
- 50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l2 (30 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6ddg
Q-score: 0.562
Belousoff MJ, Venugopal H, Wright A, Seoner S, Stuart I, Stubenrauch C, Bamert RS, Lupton DW, Lithgow T
Chem Med Chem (2019) 14 pp. 527-531 [ DOI: doi:10.1002/cmdc.201900042 Pubmed: 30667174 ]
- 50s ribosomal protein l16 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal subunit from mrsa in complex with oxazolidinone lzd-5 (Complex from Staphylococcus aureus)
- 50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l27 (9 kDa, Protein from Staphylococcus aureus)
- 5s rrna (36 kDa, RNA from Staphylococcus aureus)
- 50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l18 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l35 (7 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l25 (23 kDa, Protein from Staphylococcus aureus)
- 2-chloro-n-({(5s)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide (371 Da, Ligand)
- 50s ribosomal protein l32 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l19 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l29 (8 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l33 (5 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus)
- 23s rrna (946 kDa, RNA from Staphylococcus aureus)
- 50s ribosomal protein l34 (5 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l2 (30 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus)
Type II secretin from Enteropathogenic Escherichia coli - GspD
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 5w68
Q-score: 0.449
Hay ID, Belousoff MJ, Dunstan RA, Bamert RS, Lithgow T
J Bacteriol (2018) 200 [ DOI: doi:10.1128/JB.00521-17 Pubmed: 29084860 ]
Type II secretin from Enteropathogenic Escherichia coli - GspD
Hay ID, Belousoff MJ, Dunstan RA, Bamert RS, Lithgow T
J Bacteriol (2018) 200 [ DOI: doi:10.1128/JB.00521-17 Pubmed: 29084860 ]
Methicillin Resistant, Linezolid resistant Staphylococcus aureus 70S ribosome (delta S145 uL3)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 5t7v
Q-score: 0.462
Belousoff MJ, Eyal Z, Radjainia M, Ahmed T, Bamert RS, Matzov D, Bashan A, Zimmerman E, Mishra S, Cameron D, Elmlund H, Peleg AY, Bhushan S, Lithgow T, Yonath A
mBio (2017) 8 [ DOI: doi:10.1128/mBio.00395-17 Pubmed: 28487427 ]
- 50s ribosomal protein l35 (7 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l2 (29 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s20 (8 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l25 (10 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s15 (10 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s8 (14 kDa, Protein from Staphylococcus aureus)
- 16s ribosomal rna (500 kDa, RNA from Staphylococcus aureus)
- 23s ribosomal rna (945 kDa, RNA from Staphylococcus aureus)
- 5s ribosomal rna (36 kDa, RNA from Staphylococcus aureus)
- 50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s5 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l32 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l19 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus)
- Clinical isolate linezolid resistant mrsa 70s ribosome (Complex from Staphylococcus aureus)
- 50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus)
- E-site trna (23 kDa, RNA from Staphylococcus aureus)
- 30s ribosomal protein s10 (9 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s16 (8 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s17 (9 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l6 (19 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l18 (12 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l33 (5 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s4 (22 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s18 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l27 (8 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l16 (15 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l34 (5 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l29 (7 kDa, Protein from Staphylococcus aureus)
- 50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s12 (15 kDa, Protein from Staphylococcus aureus)
- Magnesium ion (24 Da, Ligand)
- 30s ribosomal protein s6 (10 kDa, Protein from Staphylococcus aureus)
- 30s ribosomal protein s11 (12 kDa, Protein from Staphylococcus aureus)
Methicillin sensitive Staphylococcus aureus 70S ribosome
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 5tcu
Q-score: 0.431
Belousoff MJ, Eyal Z, Radjainia M, Ahmed T, Bamert RS, Matzov D, Bashan A, Zimmerman E, Mishra S, Cameron D, Elmlund H, Peleg AY, Bhushan S, Lithgow T, Yonath A
mBio (2017) 8 [ DOI: doi:10.1128/mBio.00395-17 Pubmed: 28487427 ]
- 50s ribosomal protein l29 (7 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s12 (15 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l18 (12 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l2 (29 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s16 (9 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s7 (17 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 23s rrna (946 kDa, RNA from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s13 (12 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s19 (9 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s14 type z (7 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l25 (10 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s10 (9 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l31 type b (8 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- Mrna (4 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l5 (18 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s20 (8 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- E-site trna chain (24 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s9 (14 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s8 (14 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s5 (16 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- Methicillin sensitive staphylococcus aureus 70s ribosome (atcc 35556) (Complex from Staphylococcus aureus)
- 16s rrna (502 kDa, RNA from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s4 (22 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l33 1 (5 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s17 (9 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l35 (6 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s15 (10 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- P-site trna chain (24 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
- Paromomycin (615 Da, Ligand)
- 30s ribosomal protein s11 (12 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l27 (8 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 5s rrna chain (36 kDa, RNA from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l19 (12 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s3 (22 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l6 (19 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l16 (15 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l32 (5 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s6 (11 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 30s ribosomal protein s18 (6 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- 50s ribosomal protein l34 (5 kDa, Protein from Staphylococcus aureus (strain NCTC 8325))
- Magnesium ion (24 Da, Ligand)