Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8go9
Q-score: 0.46
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]
- Fab30 (Complex from Mus musculus)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Beta-arrestin-2 (47 kDa, Protein from Bos taurus)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Beta-arrestin2 (Complex from Bos taurus)
- Atypical chemokine receptor 2 (Complex from Homo sapiens)
- Atypical chemokine receptor 2 (2 kDa, Protein from Homo sapiens)
- Peptide bound beta-arrestin2 in complex with fab30 (190 kDa, Complex)
Structure of beta-arrestin2 in complex with D6Rpp (Local Refine)
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 8j8v
Q-score: 0.514
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK
Science (2024) 383 pp. 101-108 [ DOI: doi:10.1126/science.adj3347 Pubmed: 38175886 ]
- Fab30 (Complex from Mus musculus)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Beta-arrestin-2 (47 kDa, Protein from Bos taurus)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Beta-arrestin2 (Complex from Bos taurus)
- Atypical chemokine receptor 2 (Complex from Homo sapiens)
- Atypical chemokine receptor 2 (2 kDa, Protein from Homo sapiens)
- Beta-arrestin2 in complex with d6rpp (Complex)
Structure of C5a-pep bound mouse C5aR1 in complex with Go
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 8hpt
Q-score: 0.491
Yadav MK, Maharana J, Yadav R, Saha S, Sarma P, Soni C, Singh V, Saha S, Ganguly M, Li XX, Mohapatra S, Mishra S, Khant HA, Chami M, Woodruff TM, Banerjee R, Shukla AK, Gati C
Cell (2023) 186 pp. 4956-4973.e21 [ Pubmed: 37852260 DOI: doi:10.1016/j.cell.2023.09.020 ]
- Antibody fragment scfv16 (27 kDa, Protein from Mus musculus)
- Synthetic peptide (Complex)
- C5a anaphylatoxin chemotactic receptor 1 (44 kDa, Protein from Mus musculus)
- Mea-lys-pro-zal-alc-dar (869 Da, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- Antibody fragment (Complex from Mus musculus)
- C5a anaphylatoxin chemotactic receptor 1 (Complex from Mus musculus)
- Gpcr-g protein in complex with a synthetic peptide agonist (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
Structure of a GPCR-G protein in complex with a natural peptide agonist
Resolution: 3.89 Å
EM Method: Single-particle
Fitted PDBs: 8hqc
Q-score: 0.443
Yadav MK, Maharana J, Yadav R, Saha S, Sarma P, Soni C, Singh V, Saha S, Ganguly M, Li XX, Mohapatra S, Mishra S, Khant HA, Chami M, Woodruff TM, Banerjee R, Shukla AK, Gati C
Cell (2023) 186 pp. 4956-4973.e21 [ Pubmed: 37852260 DOI: doi:10.1016/j.cell.2023.09.020 ]
- C5a anaphylatoxin chemotactic receptor 1 (44 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Gpcr-g protein in complex with a natural peptide agonist (Complex)
- Guanine nucleotide-binding protein g(o) subunit alpha (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
- C5a anaphylatoxin (8 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- C5a anaphylatoxin (Complex from Homo sapiens)
- Antibody fragment (Complex from Mus musculus)
- C5a anaphylatoxin chemotactic receptor 1 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Antibody fragment (27 kDa, Protein from Mus musculus)
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8go8
Q-score: 0.457
Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK
Mol Cell (2023) 83 pp. 2091-2107.e7 [ Pubmed: 37209686 DOI: doi:10.1016/j.molcel.2023.04.025 ]
- Peptide bound beta-arrestin1 in complex with fab30 (190 kDa, Complex)
- Beta-arrestin-1 (47 kDa, Protein from Rattus norvegicus)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Fab30 (Complex from Mus musculus)
- C5a anaphylatoxin chemotactic receptor 1 (2 kDa, Protein from Homo sapiens)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Beta-arrestin1 (Complex from Rattus norvegicus)
- C5a anaphylatoxin chemotactic receptor 1 (Complex from Homo sapiens)
Resolution: 4.18 Å
EM Method: Single-particle
Fitted PDBs: 8goc
Q-score: 0.367
Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK
Mol Cell (2023) 83 pp. 2091-2107.e7 [ Pubmed: 37209686 DOI: doi:10.1016/j.molcel.2023.04.025 ]
- Vasopressin v2 receptor (3 kDa, Protein from Homo sapiens)
- Fab30 (Complex from Mus musculus)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Beta-arrestin-2 (47 kDa, Protein from Bos taurus)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Beta-arrestin2 (Complex from Bos taurus)
- Vasopressin v2 receptor (Complex from Homo sapiens)
- Peptide3 bound beta-arrestin2 in complex with fab30 (280 kDa, Complex)
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8i0n
Q-score: 0.513
Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK
Mol Cell (2023) 83 pp. 2091-2107.e7 [ Pubmed: 37209686 DOI: doi:10.1016/j.molcel.2023.04.025 ]
- Beta-arrestin-1 (47 kDa, Protein from Rattus norvegicus)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Fab30 (Complex from Mus musculus)
- C5a anaphylatoxin chemotactic receptor 1 (2 kDa, Protein from Homo sapiens)
- Peptide 1 bound beta-arrestin1 in complex with fab30 - local refine (190 kDa, Complex)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Beta-arrestin1 (Complex from Rattus norvegicus)
- C5a anaphylatoxin chemotactic receptor 1 (Complex from Homo sapiens)
Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 8i10
Q-score: 0.434
Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK
Mol Cell (2023) 83 pp. 2091-2107.e7 [ Pubmed: 37209686 DOI: doi:10.1016/j.molcel.2023.04.025 ]
- Fab30 (Complex from Mus musculus)
- Fab30 heavy chain (25 kDa, Protein from Mus musculus)
- Beta-arrestin-2 (47 kDa, Protein from Bos taurus)
- Fab30 light chain (23 kDa, Protein from Mus musculus)
- Vasopressin v2 receptor (3 kDa, Protein from Homo sapiens)
- Beta-arrestin2 (Complex from Bos taurus)
- Peptide3 bound beta-arrestin2 in complex with fab30 - local refine (280 kDa, Complex)
- Vasopressin v2 receptor phosphopeptide (Complex from Homo sapiens)