Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 9bra
Q-score: 0.284
Wang C, Jiang W, Leitz J, Yang K, Esquivies L, Wang X, Shen X, Held RG, Adams DJ, Basta T, Hampton L, Jian R, Jiang L, Stowell MHB, Baumeister W, Guo Q, Brunger AT
Nature (2024) 631 pp. 899-904 [ Pubmed: 38838737 DOI: doi:10.1038/s41586-024-07610-x ]
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Mus musculus)
- V-type proton atpase subunit g 2 (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit h (55 kDa, Protein from Mus musculus)
- V-type proton atpase 116 kda subunit a 1 (96 kDa, Protein from Mus musculus)
- V-type proton atpase 21 kda proteolipid subunit c'' (21 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d 1 (40 kDa, Protein from Mus musculus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d (28 kDa, Protein from Mus musculus)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Mus musculus)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Mus musculus)
- Synaptophysin (34 kDa, Protein from Mus musculus)
- Renin receptor cytoplasmic fragment (39 kDa, Protein from Mus musculus)
- Ribonuclease kappa (11 kDa, Protein from Mus musculus)
- V-type proton atpase subunit f (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit c 1 (43 kDa, Protein from Mus musculus)
- Mouse brain isolated glutamatergic synaptic vesicles (Cellular component from Mus musculus)
Intact V-ATPase State 3 and synaptophysin complex in mouse brain isolated synaptic vesicles
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 9brq
Q-score: 0.271
Wang C, Jiang W, Leitz J, Yang K, Esquivies L, Wang X, Shen X, Held RG, Adams DJ, Basta T, Hampton L, Jian R, Jiang L, Stowell MHB, Baumeister W, Guo Q, Brunger AT
Nature (2024) 631 pp. 899-904 [ Pubmed: 38838737 DOI: doi:10.1038/s41586-024-07610-x ]
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Mus musculus)
- V-type proton atpase subunit g 2 (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit h (55 kDa, Protein from Mus musculus)
- V-type proton atpase 21 kda proteolipid subunit c'' (21 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d 1 (40 kDa, Protein from Mus musculus)
- V-type proton atpase 116 kda subunit a 1 (96 kDa, Protein from Mus musculus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d (28 kDa, Protein from Mus musculus)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Mus musculus)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Mus musculus)
- Synaptophysin (34 kDa, Protein from Mus musculus)
- Renin receptor cytoplasmic fragment (39 kDa, Protein from Mus musculus)
- Ribonuclease kappa (11 kDa, Protein from Mus musculus)
- V-type proton atpase subunit f (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit c 1 (43 kDa, Protein from Mus musculus)
- Mouse brain isolated glutamatergic synaptic vesicles (Cellular component from Mus musculus)
Intact V-ATPase State 3 in synaptophysin knock-out isolated synaptic vesicles
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 9brr
Q-score: 0.3
Wang C, Jiang W, Leitz J, Yang K, Esquivies L, Wang X, Shen X, Held RG, Adams DJ, Basta T, Hampton L, Jian R, Jiang L, Stowell MHB, Baumeister W, Guo Q, Brunger AT
Nature (2024) 631 pp. 899-904 [ Pubmed: 38838737 DOI: doi:10.1038/s41586-024-07610-x ]
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Mus musculus)
- V-type proton atpase subunit g 2 (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit h (55 kDa, Protein from Mus musculus)
- V-type proton atpase 21 kda proteolipid subunit c'' (21 kDa, Protein from Mus musculus)
- V-type proton atpase 116 kda subunit a 1 (96 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Mus musculus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d (28 kDa, Protein from Mus musculus)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Mus musculus)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Mus musculus)
- Renin receptor cytoplasmic fragment (39 kDa, Protein from Mus musculus)
- Ribonuclease kappa (11 kDa, Protein from Mus musculus)
- V-type proton atpase subunit f (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit c 1 (43 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d 1 (40 kDa, Protein from Mus musculus)
- Synaptophysin knock-out mouse brain isolated glutamatergic synaptic vesicles (Cellular component from Mus musculus)
Intact V-ATPase State 2 in synaptophysin knock-out isolated synaptic vesicles
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 9brs
Q-score: 0.277
Wang C, Jiang W, Leitz J, Yang K, Esquivies L, Wang X, Shen X, Held RG, Adams DJ, Basta T, Hampton L, Jian R, Jiang L, Stowell MHB, Baumeister W, Guo Q, Brunger AT
Nature (2024) 631 pp. 899-904 [ Pubmed: 38838737 DOI: doi:10.1038/s41586-024-07610-x ]
- V-type proton atpase subunit g 2 (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Mus musculus)
- V-type proton atpase 116 kda subunit a 1 (96 kDa, Protein from Mus musculus)
- V-type proton atpase subunit h (55 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Mus musculus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Mus musculus)
- V-type proton atpase 21 kda proteolipid subunit c'' (21 kDa, Protein from Mus musculus)
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d (28 kDa, Protein from Mus musculus)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Mus musculus)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Mus musculus)
- Renin receptor cytoplasmic fragment (39 kDa, Protein from Mus musculus)
- Ribonuclease kappa (11 kDa, Protein from Mus musculus)
- V-type proton atpase subunit f (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit c 1 (43 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d 1 (40 kDa, Protein from Mus musculus)
- Synaptophysin knock-out mouse brain isolated glutamatergic synaptic vesicles (Cellular component from Mus musculus)
Intact V-ATPase State 1 and synaptophysin complex in mouse brain isolated synaptic vesicles
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 9brt
Q-score: 0.271
Wang C, Jiang W, Leitz J, Yang K, Esquivies L, Wang X, Shen X, Held RG, Adams DJ, Basta T, Hampton L, Jian R, Jiang L, Stowell MHB, Baumeister W, Guo Q, Brunger AT
Nature (2024) 631 pp. 899-904 [ Pubmed: 38838737 DOI: doi:10.1038/s41586-024-07610-x ]
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Mus musculus)
- V-type proton atpase subunit g 2 (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit h (55 kDa, Protein from Mus musculus)
- V-type proton atpase 116 kda subunit a 1 (96 kDa, Protein from Mus musculus)
- V-type proton atpase 21 kda proteolipid subunit c'' (21 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d 1 (40 kDa, Protein from Mus musculus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d (28 kDa, Protein from Mus musculus)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Mus musculus)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Mus musculus)
- Synaptophysin (34 kDa, Protein from Mus musculus)
- Renin receptor cytoplasmic fragment (39 kDa, Protein from Mus musculus)
- Ribonuclease kappa (11 kDa, Protein from Mus musculus)
- V-type proton atpase subunit f (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit c 1 (43 kDa, Protein from Mus musculus)
- Mouse brain isolated glutamatergic synaptic vesicles (Cellular component from Mus musculus)
Intact V-ATPase State 1 in synaptophysin knock-out isolated synaptic vesicles
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 9bru
Q-score: 0.262
Wang C, Jiang W, Leitz J, Yang K, Esquivies L, Wang X, Shen X, Held RG, Adams DJ, Basta T, Hampton L, Jian R, Jiang L, Stowell MHB, Baumeister W, Guo Q, Brunger AT
Nature (2024) 631 pp. 899-904 [ Pubmed: 38838737 DOI: doi:10.1038/s41586-024-07610-x ]
- V-type proton atpase subunit g 2 (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Mus musculus)
- V-type proton atpase 116 kda subunit a 1 (96 kDa, Protein from Mus musculus)
- V-type proton atpase subunit h (55 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Mus musculus)
- V-type proton atpase 21 kda proteolipid subunit c'' (21 kDa, Protein from Mus musculus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Mus musculus)
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d (28 kDa, Protein from Mus musculus)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Mus musculus)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Mus musculus)
- Renin receptor cytoplasmic fragment (39 kDa, Protein from Mus musculus)
- Ribonuclease kappa (11 kDa, Protein from Mus musculus)
- V-type proton atpase subunit f (13 kDa, Protein from Mus musculus)
- V-type proton atpase subunit c 1 (43 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d 1 (40 kDa, Protein from Mus musculus)
- Synaptophysin knock-out mouse brain isolated glutamatergic synaptic vesicles (Cellular component from Mus musculus)
V0-only V-ATPase in synaptophysin gene knock-out mouse brain isolated synaptic vesicles
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9bry
Q-score: 0.373
Wang C, Jiang W, Leitz J, Yang K, Esquivies L, Wang X, Shen X, Held RG, Adams DJ, Basta T, Hampton L, Jian R, Jiang L, Stowell MHB, Baumeister W, Guo Q, Brunger AT
Nature (2024) 631 pp. 899-904 [ Pubmed: 38838737 DOI: doi:10.1038/s41586-024-07610-x ]
- Renin receptor cytoplasmic fragment (32 kDa, Protein from Mus musculus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Mus musculus)
- V-type proton atpase 116 kda subunit a 1 (96 kDa, Protein from Mus musculus)
- V-type proton atpase 21 kda proteolipid subunit c'' (21 kDa, Protein from Mus musculus)
- Syptophysin gene knock-out mouse brain isolated glutamatergic synaptic vesicles (Cellular component from Mus musculus)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Mus musculus)
- Beta-d-mannopyranose (180 Da, Ligand)
- Ribonuclease kappa (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- V-type proton atpase subunit d 1 (40 kDa, Protein from Mus musculus)
V0-only V-ATPase and synaptophysin complex in mouse brain isolated synaptic vesicles
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 9brz
Q-score: 0.385
Wang C, Jiang W, Leitz J, Yang K, Esquivies L, Wang X, Shen X, Held RG, Adams DJ, Basta T, Hampton L, Jian R, Jiang L, Stowell MHB, Baumeister W, Guo Q, Brunger AT
Nature (2024) 631 pp. 899-904 [ Pubmed: 38838737 DOI: doi:10.1038/s41586-024-07610-x ]
- V-type proton atpase subunit s1 (51 kDa, Protein from Mus musculus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Mus musculus)
- V-type proton atpase subunit d 1 (40 kDa, Protein from Mus musculus)
- V-type proton atpase 116 kda subunit a 1 (96 kDa, Protein from Mus musculus)
- V-type proton atpase 21 kda proteolipid subunit c'' (21 kDa, Protein from Mus musculus)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Mus musculus)
- Synaptophysin (34 kDa, Protein from Mus musculus)
- Renin receptor cytoplasmic fragment (39 kDa, Protein from Mus musculus)
- Ribonuclease kappa (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Mouse brain isolated glutamatergic synaptic vesicles (Cellular component from Mus musculus)
Cryo-EM structure of Torpedo acetylcholine receptor in apo form
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7smm
Q-score: 0.622
Rahman MM, Basta T, Teng J, Lee M, Worrell BT, Stowell MHB, Hibbs RE
Nat Struct Mol Biol (2022) 29 pp. 386-394 [ DOI: doi:10.1038/s41594-022-00737-3 Pubmed: 35301478 ]
- Nonane (128 Da, Ligand)
- Water (18 Da, Ligand)
- Acetylcholine receptor subunit alpha (50 kDa, Protein from Tetronarce californica)
- Acetylcholine receptor subunit beta (53 kDa, Protein from Tetronarce californica)
- Acetylcholine receptor subunit delta (57 kDa, Protein from Tetronarce californica)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Torpedo acetylcholine receptor in apo form (Complex from Tetronarce californica)
- Cholesterol (386 Da, Ligand)
- Acetylcholine receptor subunit gamma (56 kDa, Protein from Tetronarce californica)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of Torpedo acetylcholine receptor in apo form with added cholesterol
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 7smq
Q-score: 0.583
Rahman MM, Basta T, Teng J, Lee M, Worrell BT, Stowell MHB, Hibbs RE
Nat Struct Mol Biol (2022) 29 pp. 386-394 [ DOI: doi:10.1038/s41594-022-00737-3 Pubmed: 35301478 ]
- Nonane (128 Da, Ligand)
- Acetylcholine receptor subunit alpha (50 kDa, Protein from Tetronarce californica)
- Acetylcholine receptor subunit delta (57 kDa, Protein from Tetronarce californica)
- Acetylcholine receptor subunit beta (53 kDa, Protein from Tetronarce californica)
- Torpedo acetylcholine receptor in apo form plus cholesterol (Complex from Tetronarce californica)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Acetylcholine receptor subunit gamma (56 kDa, Protein from Tetronarce californica)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)