Cryo-EM structure of the human BRISC dimer complex bound to compound FX-171-C
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 8pvy
Q-score: 0.332
Chandler F, Reddy P, Bhutda S, Ross R, Walden M, Walker K, Cassel J, Prakesch M, Datti A, Campbell L, Foglizzo M, Bell L, Ault J, Al-awar R, Calabrese A, Sicheri F, Del Galdo F, Salvino J, Greenberg R, Zeqiraj E
To Be Published
- Zinc ion (65 Da, Ligand)
- Brisc and brca1-a complex member 1 (29 kDa, Protein from Homo sapiens)
- N-[(1r,5s)-3-azabicyclo[3.1.0]hexan-6-yl]-1-[2,6-bis(chloranyl)phenyl]carbonyl-4-[[2,6-bis(chloranyl)phenyl]carbonylamino]pyrazole-3-carboxamide (553 Da, Ligand)
- Brisc and brca1-a complex member 2 (43 kDa, Protein from Homo sapiens)
- Brisc dimer in complex with inhibitor fx-171-c (654 kDa, Complex from Homo sapiens)
- Lys-63-specific deubiquitinase brcc36 (35 kDa, Protein from Homo sapiens)
- Brisc complex subunit abraxas 2 (31 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human BRISC dimer complex bound to compound JMS-175-2
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8py2
Q-score: 0.281
Chandler F, Reddy P, Bhutda S, Ross R, Walden M, Walker K, Cassel J, Prakesch M, Campbell L, Foglizzo M, Bell L, Ault J, Al-awar R, Calabrese A, Sicheri F, Del Galdo F, Salvino J, Greenberg R, Zeqiraj E
To Be Published
- Brisc and brca1-a complex member 2 (43 kDa, Protein from Homo sapiens)
- Brisc dimer in complex with inhibitor jms-175-2 (654 kDa, Complex from Homo sapiens)
- Brisc and brca1-a complex member 1 (29 kDa, Protein from Homo sapiens)
- Lys-63-specific deubiquitinase brcc36 (36 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Brisc complex subunit abraxas 2 (31 kDa, Protein from Homo sapiens)
- 1-[2,6-bis(chloranyl)phenyl]carbonyl-4-[[2,6-bis(chloranyl)phenyl]carbonylamino]-n-piperidin-4-yl-pyrazole-3-carboxamide (555 Da, Ligand)
The Capsid of Canine Minute Virus
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8tu0
Q-score: 0.564
Velez M, Mietzsch M, Hsi J, Bell L, Chipman P, Fu X, McKenna R
Viruses (2023) 15 [ Pubmed: 37766206 DOI: doi:10.3390/v15091799 ]
- Vp2 (63 kDa, Protein from Canine minute virus)
- Canine minute virus (Virus from Canine minute virus)
The Capsid of Porcine Bocavirus 1
Resolution: 2.31 Å
EM Method: Single-particle
Fitted PDBs: 8tu1
Q-score: 0.703
Velez M, Mietzsch M, Hsi J, Bell L, Chipman P, Fu X, McKenna R
Viruses (2023) 15 [ DOI: doi:10.3390/v15091799 Pubmed: 37766206 ]
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8tu2
Q-score: 0.663
Velez M, Mietzsch M, Hsi J, Bell L, Chipman P, Fu X, McKenna R
Viruses (2023) 15 [ Pubmed: 37766206 DOI: doi:10.3390/v15091799 ]
- Rat bocavirus (Virus from Rat bocavirus)
- Vp2 (63 kDa, Protein from Rat bocavirus)