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primary_citation_author:"Bogdanovic N"
Domoate-bound GluK2 kainate receptor in partially-open conformation 1
Release date: March 13, 2024
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8gc2
Q-score: 0.311
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8gc2
Q-score: 0.311
To Be Published
Sample:
- Glutamate receptor ionotropic, kainate 2 (98 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- (2s,3s,4s)-2-carboxy-4-[(1z,3e,5r)-5-carboxy-1-methyl-1,3-hexadienyl]-3-pyrrolidineacetic acid (311 Da, Ligand)
- Homotetrameric gluk2 bound with domoate state 1 (Complex from Rattus norvegicus)
Domote-bound GluK2 kainate receptors in partially-open conformation 2
Release date: March 13, 2024
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8gc3
Q-score: 0.344
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8gc3
Q-score: 0.344
To Be Published
Sample:
- (2s,3s,4s)-2-carboxy-4-[(1z,3e,5r)-5-carboxy-1-methyl-1,3-hexadienyl]-3-pyrrolidineacetic acid (311 Da, Ligand)
- Glutamate receptor ionotropic, kainate 2 (98 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Homotetrameric gluk2 bound with doq state 1 (Complex from Rattus norvegicus)
Domoate-bound GluK2 kainate receptor in partially-open conformation 3
Release date: March 13, 2024
Resolution: 3.93 Å
EM Method: Single-particle
Fitted PDBs: 8gc4
Q-score: 0.327
Resolution: 3.93 Å
EM Method: Single-particle
Fitted PDBs: 8gc4
Q-score: 0.327
To Be Published
Sample:
- Glutamate receptor ionotropic, kainate 2 (98 kDa, Protein from Rattus norvegicus)
- Homotetrameric gluk2 bound with doq state 4 (Complex from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- (2s,3s,4s)-2-carboxy-4-[(1z,3e,5r)-5-carboxy-1-methyl-1,3-hexadienyl]-3-pyrrolidineacetic acid (311 Da, Ligand)
Domoate-bound GluK2 kainate receptors in non-active conformation
Release date: March 13, 2024
Resolution: 3.93 Å
EM Method: Single-particle
Fitted PDBs: 8gc5
Q-score: 0.353
Resolution: 3.93 Å
EM Method: Single-particle
Fitted PDBs: 8gc5
Q-score: 0.353
To Be Published
Sample:
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Homotetrameric gluk2 bound with doq state 4 (Complex from Rattus norvegicus)
- (2s,3s,4s)-2-carboxy-4-[(1z,3e,5r)-5-carboxy-1-methyl-1,3-hexadienyl]-3-pyrrolidineacetic acid (311 Da, Ligand)
- Glutamate receptor ionotropic, kainate 2 (98 kDa, Protein from Rattus norvegicus)
- Alpha-d-mannopyranose (180 Da, Ligand)
cryo-EM structure of homomeric kainate receptor GluK2 in resting (apo) state
Release date: Nov. 8, 2023
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 8f0o
Q-score: 0.361
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 8f0o
Q-score: 0.361
To Be Published
Sample: