CON-S ch.ds.SOSIP HIV trimer bound to DH840 Fab
Cai F, Chen WH, Wu W, Jones J, Misook C, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Hernandez G, Nelson RW, Scearce R, Seaman M, Moody MA, Santra S, Wiehe KJ, Tomaras GD, Wagh K, Korber B, Bonsignori M, Montefiori DC, Haynes BF, de Val N, Joyce GM, Saunders KO
To Be Published
CON-S ch.DS.SOSIP HIV trimer bound to DH842 Fab
Cai F, Chen WH, Wu W, Jones J, Misook C, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Hernandez G, Nelson RW, Scearce R, Seaman M, Moody MA, Santra S, Wiehe KJ, Tomaras GD, Wagh K, Korber B, Bonsignori M, Montefiori DC, Haynes BF, de Val N, Joyce GM, Saunders KO
To Be Published
CON-S ch.DS.SOSIP HIV trimer bound to DH845 Fab
Cai F, Chen WH, Wu W, Jones J, Misook C, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Hernandez G, Nelson RW, Scearce R, Seaman M, Moody MA, Santra S, Wiehe KJ, Tomaras GD, Wagh K, Korber B, Bonsignori M, Montefiori DC, Haynes BF, de Val N, Joyce GM, Saunders KO
To Be Published
CON-S ch.DS.SOSIP HIV trimer bound to DH846 Fab
Cai F, Chen WH, Wu W, Jones J, Misook C, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Hernandez G, Nelson RW, Scearce R, Seaman M, Moody MA, Santra S, Wiehe KJ, Tomaras GD, Wagh K, Korber B, Bonsignori M, Montefiori DC, Haynes BF, de Val N, Joyce GM, Saunders KO
To Be Published
Cryo-EM structure of SHIV-elicited RHA1.V2.01 in complex with HIV-1 Env BG505 DS-SOSIP.664
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6xrt
Q-score: 0.322
Roark RS, Li H, Williams WB, Chug H, Mason RD, Gorman J, Wang S, Lee FH, Rando J, Bonsignori M, Hwang KK, Saunders KO, Wiehe K, Moody MA, Hraber PT, Wagh K, Giorgi EE, Russell RM, Bibollet-Ruche F, Liu W, Connell J, Smith AG, DeVoto J, Murphy AI, Smith J, Ding W, Zhao C, Chohan N, Okumura M, Rosario C, Ding Y, Lindemuth E, Bauer AM, Bar KJ, Ambrozak D, Chao CW, Chuang GY, Geng H, Lin BC, Louder MK, Nguyen R, Zhang B, Lewis MG, Raymond DD, Doria-Rose NA, Schramm CA, Douek DC, Roederer M, Kepler TB, Kelsoe G, Mascola JR, Kwong PD, Korber BT, Harrison SC, Haynes BF, Hahn BH, Shaw GM
Science (2021) 371 [ Pubmed: 33214287 DOI: doi:10.1126/science.abd2638 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of shiv-elicited rha1.v2.01 in complex with hiv-1 env bg505 ds-sosip (Complex)
- Cryo-em structure of shiv-elicited rha1.v2.01 in complex with hiv-1 env bg505 ds-sosip.664 (Complex from Human immunodeficiency virus 1)
- Hiv-1 envelope glycoprotein bg505 sosip.664 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Vrc01.23 light chain (11 kDa, Protein from Macaca mulatta)
- Vrc01.23 heavy chain (14 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
92BR SOSIP.664 trimer in complex with DH270.1 Fab
Bonsignori M, Kreider EF, Fera D, Meyerhoff RR, Bradley T, Wiehe K, Alam SM, Aussedat B, Walkowicz WE, Hwang KK, Saunders KO, Zhang R, Gladden MA, Monroe A, Kumar A, Xia SM, Cooper M, Louder MK, McKee K, Bailer RT, Pier BW, Jette CA, Kelsoe G, Williams WB, Morris L, Kappes J, Wagh K, Kamanga G, Cohen MS, Hraber PT, Montefiori DC, Trama A, Liao HX, Kepler TB, Moody MA, Gao F, Danishefsky SJ, Mascola JR, Shaw GM, Hahn BH, Harrison SC, Korber BT, Haynes BF
Sci Transl Med (2017) 9 [ DOI: doi:10.1126/scitranslmed.aai7514 Pubmed: 28298420 ]