Tau Paired Helical Filament from Alzheimer's Disease incubated with EGCG for 3 hours
Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Diskson DW, Vinters HV, Eisenberg DS
Nat Commun (2022) 13 pp. 5451-12 [ Pubmed: 36114178 DOI: 10.1038/s41467-022-32951-4 ]
Image sets:
Tau Paired Helical Filament from Alzheimer's Disease incubated 1 hr. with EGCG
Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Diskson DW, Vinters HV, Eisenberg DS
Nat Commun (2022) 13 pp. 5451-12 [ Pubmed: 36114178 DOI: 10.1038/s41467-022-32951-4 ]
Image sets:
Tau Paired Helical Filament from Alzheimer's Disease not incubated with EGCG
Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Diskson DW, Vinters HV, Eisenberg DS
Nat. Commun. (2022) 13 pp. 1-12 [ Pubmed: 36114178 DOI: 10.1038/s41467-022-32951-4 ]
Image sets:
Tau Paired Helical Filament from Alzheimer's Disease not incubated with EGCG
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 7upe
Q-score: 0.44
Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Dickson DW, Vinters HV, Eisenberg DS
Nat Commun (2022) 13 pp. 5451-5451 [ DOI: doi:10.1038/s41467-022-32951-4 Pubmed: 36114178 ]
Tau Paired Helical Filament from Alzheimer's Disease incubated 1 hr. with EGCG
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 7upf
Q-score: 0.452
Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Dickson DW, Vinters HV, Eisenberg DS
Nat Commun (2022) 13 pp. 5451-5451 [ DOI: doi:10.1038/s41467-022-32951-4 Pubmed: 36114178 ]
Tau Paired Helical Filament from Alzheimer's Disease incubated with EGCG for 3 hours
Resolution: 3.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 7upg
Q-score: 0.392
Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Dickson DW, Vinters HV, Eisenberg DS
Nat Commun (2022) 13 pp. 5451-5451 [ DOI: doi:10.1038/s41467-022-32951-4 Pubmed: 36114178 ]
- Tau paired helical filament from alzheimer's disease incubated with egcg for 3 hours (Tissue from Homo sapiens)
- Isoform tau-f of microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- (2r,3r)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2h-chromen-3-yl 3,4,5-trihydroxybenzoate (458 Da, Ligand)
KVQIINKKLD, Structure of the amyloid spine from microtubule associated protein tau Repeat 2
Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS
Nat Chem (2018) 10 pp. 170-176 [ Pubmed: 29359764 DOI: doi:10.1038/nchem.2889 ]
- Kvqiinkkld tau peptide (Cellular component from Homo sapiens)
- Water (18 Da, Ligand)
- Microtubule-associated protein tau (1 kDa, Protein from Homo sapiens)
VQIINK, Structure of the amyloid-spine from microtubule associated protein tau Repeat 2
Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS
Nat Chem (2018) 10 pp. 170-176 [ Pubmed: 29359764 DOI: doi:10.1038/nchem.2889 ]
- Microtubule-associated protein tau (714 Da, Protein from Homo sapiens)
- Vqiink tau peptide (Cellular component from Homo sapiens)