Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8spa
Q-score: 0.527
Flores MD, Sawaya MR, Boyer DR, Zink S, Fioriti L, Rodriguez JA
To Be Published
- Helical assembly of cpeb3 prion-like domain 1 (23 MDa, Complex from Homo sapiens)
- Cytoplasmic polyadenylation element-binding protein 3 (5 kDa, Protein from Homo sapiens)
Resolution: 2.84 Å
EM Method: Helical reconstruction
Fitted PDBs: 8teq
Q-score: 0.625
Rosenberg GM, Abskharon R, Boyer DR, Ge P, Sawaya MR, Eisenberg DS
Pnas Nexus (2023) 2 pp. pgad402-pgad402 [ DOI: doi:10.1093/pnasnexus/pgad402 Pubmed: 38077690 ]
Resolution: 2.59 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ter
Q-score: 0.676
Rosenberg GM, Abskharon R, Boyer DR, Ge P, Sawaya MR, Eisenberg DS
Pnas Nexus (2023) 2 pp. pgad402-pgad402 [ DOI: doi:10.1093/pnasnexus/pgad402 Pubmed: 38077690 ]
- Water (18 Da, Ligand)
- Trk-fused gene protein low complexity domain p285l mutant (40 kDa, Protein from Homo sapiens)
- Amyloid fibril of protein tfg p285l (Complex from Homo sapiens)
Resolution: 3.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ec7
Q-score: 0.374
Lu J, Ge P, Sawaya MR, Hughes MP, Boyer DR, Cao Q, Abskharon R, Cascio D, Tayeb-Fligelman E, Eisenberg DS
J Biol Chem (2023) 300 pp. 105531-105531 [ Pubmed: 38072051 DOI: doi:10.1016/j.jbc.2023.105531 ]
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 8du2
Q-score: 0.509
Lu J, Ge P, Sawaya MR, Hughes MP, Boyer DR, Cao Q, Abskharon R, Cascio D, Tayeb-Fligelman E, Eisenberg DS
J Biol Chem (2023) 300 pp. 105531-105531 [ Pubmed: 38072051 DOI: doi:10.1016/j.jbc.2023.105531 ]
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8duw
Q-score: 0.551
Lu J, Ge P, Sawaya MR, Hughes MP, Boyer DR, Cao Q, Abskharon R, Cascio D, Tayeb-Fligelman E, Eisenberg DS
J Biol Chem (2023) 300 pp. 105531-105531 [ Pubmed: 38072051 DOI: doi:10.1016/j.jbc.2023.105531 ]
Tau Paired Helical Filament from Alzheimer's Disease not incubated with EGCG
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 7upe
Q-score: 0.44
Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Dickson DW, Vinters HV, Eisenberg DS
Nat Commun (2022) 13 pp. 5451-5451 [ DOI: doi:10.1038/s41467-022-32951-4 Pubmed: 36114178 ]
Tau Paired Helical Filament from Alzheimer's Disease incubated 1 hr. with EGCG
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 7upf
Q-score: 0.452
Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Dickson DW, Vinters HV, Eisenberg DS
Nat Commun (2022) 13 pp. 5451-5451 [ DOI: doi:10.1038/s41467-022-32951-4 Pubmed: 36114178 ]
Tau Paired Helical Filament from Alzheimer's Disease incubated with EGCG for 3 hours
Resolution: 3.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 7upg
Q-score: 0.392
Seidler PM, Murray KA, Boyer DR, Ge P, Sawaya MR, Hu CJ, Cheng X, Abskharon R, Pan H, DeTure MA, Williams CK, Dickson DW, Vinters HV, Eisenberg DS
Nat Commun (2022) 13 pp. 5451-5451 [ DOI: doi:10.1038/s41467-022-32951-4 Pubmed: 36114178 ]
- Tau paired helical filament from alzheimer's disease incubated with egcg for 3 hours (Tissue from Homo sapiens)
- Isoform tau-f of microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- (2r,3r)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2h-chromen-3-yl 3,4,5-trihydroxybenzoate (458 Da, Ligand)
RNA-induced tau amyloid fibril
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 7sp1
Q-score: 0.429
Abskharon R, Sawaya MR, Boyer DR, Cao Q, Nguyen BA, Cascio D, Eisenberg DS
PNAS (2022) 119 pp. e2119952119-e2119952119 [ DOI: doi:10.1073/pnas.2119952119 Pubmed: 35377792 ]
- Isoform tau-f of microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- Rna (5'-r(*ap*ap*ap*ap*ap*ap*ap*ap*ap*a)-3') (3 kDa, RNA from Mus)
- Complex of tau protein and mouse rna (Complex from Homo sapiens)