Structure of lineage IV Lassa virus glycoprotein complex (strain Josiah)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8ejd
Q-score: 0.373
Perrett HR, Brouwer PJM, Hurtado J, Newby ML, Liu L, Muller-Krauter H, Muller Aguirre S, Burger JA, Bouhuijs JH, Gibson G, Messmer T, Schieffelin JS, Antanasijevic A, Boons GJ, Strecker T, Crispin M, Sanders RW, Briney B, Ward AB
Cell Rep (2023) 42 pp. 112524-112524 [ DOI: doi:10.1016/j.celrep.2023.112524 Pubmed: 37209096 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Lassa mammarenavirus gpc (275 kDa, Complex from Lassa mammarenavirus)
- Glycoprotein g1 (29 kDa, Protein from Lassa mammarenavirus)
- Glycoprotein g2 (44 kDa, Protein from Lassa mammarenavirus)
Structure of lineage VII Lassa virus glycoprotein complex (strain Togo/2016/7082)
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8ejg
Q-score: 0.429
Perrett HR, Brouwer PJM, Hurtado J, Newby ML, Liu L, Muller-Krauter H, Muller Aguirre S, Burger JA, Bouhuijs JH, Gibson G, Messmer T, Schieffelin JS, Antanasijevic A, Boons GJ, Strecker T, Crispin M, Sanders RW, Briney B, Ward AB
Cell Rep (2023) 42 pp. 112524-112524 [ DOI: doi:10.1016/j.celrep.2023.112524 Pubmed: 37209096 ]
- Glycoprotein gp1 (22 kDa, Protein from Lassa mammarenavirus)
- Glycoprotein gp2 (19 kDa, Protein from Lassa mammarenavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Lassa mammarenavirus gpc (275 kDa, Complex from Lassa mammarenavirus)
Lassa virus glycoprotein complex (Josiah) bound to 12.1F Fab
Resolution: 3.71 Å
EM Method: Single-particle
Fitted PDBs: 8ejh
Q-score: 0.406
Perrett HR, Brouwer PJM, Hurtado J, Newby ML, Liu L, Muller-Krauter H, Muller Aguirre S, Burger JA, Bouhuijs JH, Gibson G, Messmer T, Schieffelin JS, Antanasijevic A, Boons GJ, Strecker T, Crispin M, Sanders RW, Briney B, Ward AB
Cell Rep (2023) 42 pp. 112524-112524 [ DOI: doi:10.1016/j.celrep.2023.112524 Pubmed: 37209096 ]
- Alpha-d-mannopyranose (180 Da, Ligand)
- Lassa mammarenavirus gpc (425 kDa, Complex from Lassa mammarenavirus)
- Glycoprotein g1 (29 kDa, Protein from Lassa mammarenavirus)
- 12.1f fab heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glycoprotein g2 (44 kDa, Protein from Lassa mammarenavirus)
- 12.1f fab light chain (11 kDa, Protein from Homo sapiens)
Lassa virus glycoprotein complex (Josiah) bound to S370.7 Fab
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 8ejj
Q-score: 0.506
Perrett HR, Brouwer PJM, Hurtado J, Newby ML, Liu L, Muller-Krauter H, Muller Aguirre S, Burger JA, Bouhuijs JH, Gibson G, Messmer T, Schieffelin JS, Antanasijevic A, Boons GJ, Strecker T, Crispin M, Sanders RW, Briney B, Ward AB
Cell Rep (2023) 42 pp. 112524-112524 [ DOI: doi:10.1016/j.celrep.2023.112524 Pubmed: 37209096 ]
- Alpha-d-mannopyranose (180 Da, Ligand)
- Lassa mammarenavirus gpc (425 kDa, Complex from Lassa mammarenavirus)
- Glycoprotein gp1 (22 kDa, Protein from Lassa mammarenavirus)
- Glycoprotein gp2 (19 kDa, Protein from Lassa mammarenavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S370.7 heavy chain fab (14 kDa, Protein from Homo sapiens)
- S370.7 light chain fab (11 kDa, Protein from Homo sapiens)