Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8tvh
Q-score: 0.498
Wang Z, McCallum M, Yan L, Gibson CA, Sharkey W, Park YJ, Dang HV, Amaya M, Person A, Broder CC, Veesler D
PNAS (2024) 121 pp. e2314990121-e2314990121 [ Pubmed: 38593070 DOI: doi:10.1073/pnas.2314990121 ]
- Langya henipavirus postfusion fusion protein in complex with 4g5 fab (Complex from Langya virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 4g5 light chain (11 kDa, Protein from Mus musculus)
- 4g5 heavy chain (13 kDa, Protein from Mus musculus)
- Fusion glycoprotein (58 kDa, Protein from Langya virus)
Ghanaian virus fusion glycoprotein (GhV F)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8tvb
Q-score: 0.56
Wang Z, McCallum M, Yan L, Gibson CA, Sharkey W, Park YJ, Dang HV, Amaya M, Person A, Broder CC, Veesler D
PNAS (2024) 121 pp. e2314990121-e2314990121 [ DOI: doi:10.1073/pnas.2314990121 Pubmed: 38593070 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fusion glycoprotein f0,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (96 kDa, Protein from Thermotoga maritima MSB8)
- Prefusion ghanian henipavirus f fused to the i53-50a trimer via an intervening 16 gs linker (Complex from Henipavirus ghanaense)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7txz
Q-score: 0.518
Wang Z, Amaya M, Addetia A, Dang HV, Reggiano G, Yan L, Hickey AC, DiMaio F, Broder CC, Veesler D
Science (2022) 375 pp. 1373-1378 [ Pubmed: 35239409 DOI: doi:10.1126/science.abm5561 ]
- Nah1.3 fab light chain (23 kDa, Protein from Mus sp.)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nah1.3 fab heavy chain (50 kDa, Protein from Mus sp.)
- Glycoprotein g (60 kDa, Protein from Nipah henipavirus)
- Nipah virus attachment protein ectodomain in complex with nah1.3 neutralizing antibody fab fragment (Complex from Nipah henipavirus)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7ty0
Q-score: 0.439
Wang Z, Amaya M, Addetia A, Dang HV, Reggiano G, Yan L, Hickey AC, DiMaio F, Broder CC, Veesler D
Science (2022) 375 pp. 1373-1378 [ DOI: doi:10.1126/science.abm5561 Pubmed: 35239409 ]
- Nah fab light chain (23 kDa, Protein from Mus sp.)
- Glycoprotein g (60 kDa, Protein from Nipah henipavirus)
- Igh protein (50 kDa, Protein from Mus sp.)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nipah virus attachment protein ectodomain in complex with nah1.3 neutralizing antibody fab fragment (Complex from Nipah henipavirus)
Structure of the NiV F glycoprotein in complex with the 12B2 neutralizing antibody
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7ki4
Q-score: 0.537
Dang HV, Cross RW, Borisevich V, Bornholdt ZA, West BR, Chan YP, Mire CE, Da Silva SC, Dimitrov AS, Yan L, Amaya M, Navaratnarajah CK, Zeitlin L, Geisbert TW, Broder CC, Veesler D
Nat Struct Mol Biol (2021) 28 pp. 426-434 [ Pubmed: 33927387 DOI: doi:10.1038/s41594-021-00584-8 ]
- 12b2 fab light chain (23 kDa, Protein from Mus musculus)
- Niv f glycoprotein in complex with the 12b2 neutralizing antibody fab fragment (Complex from Nipah virus)
- 12b2 heavy chain (48 kDa, Protein from Mus musculus)
- Fusion glycoprotein f0 (60 kDa, Protein from Nipah virus)
Structure of the HeV F glycoprotein in complex with the 1F5 neutralizing antibody
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7ki6
Q-score: 0.575
Dang HV, Cross RW, Borisevich V, Bornholdt ZA, West BR, Chan YP, Mire CE, Da Silva SC, Dimitrov AS, Yan L, Amaya M, Navaratnarajah CK, Zeitlin L, Geisbert TW, Broder CC, Veesler D
Nat Struct Mol Biol (2021) 28 pp. 426-434 [ Pubmed: 33927387 DOI: doi:10.1038/s41594-021-00584-8 ]
- Hev f glycoprotein in complex with the 1f5 neutralizing antibody fab fragment (Complex from Hendra henipavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1f5 fab light chain (23 kDa, Protein from Mus musculus)
- 1f5 heavy chain (49 kDa, Protein from Mus musculus)
- Fusion glycoprotein f0 (59 kDa, Protein from Hendra henipavirus)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6tys
Q-score: 0.478
Dang HV, Chan YP, Park YJ, Snijder J, Da Silva SC, Vu B, Yan L, Feng YR, Rockx B, Geisbert TW, Mire CE, Broder CC, Veesler D
Nat Struct Mol Biol (2019) 26 pp. 980-987 [ Pubmed: 31570878 DOI: doi:10.1038/s41594-019-0308-9 ]
- 5b3 antibody (Complex from Mus musculus)
- 5b3 antibody light chain (11 kDa, Protein from Mus musculus)
- 5b3 antibody heavy chain (13 kDa, Protein from Mus musculus)
- Fusion glycoprotein f0 (Complex from Nipah virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nipah virus fusion (f) glycoprotein in complex with the 5b3 antibody fab fragment (Complex)
- Fusion glycoprotein f0 (59 kDa, Protein from Nipah virus)