Ghanaian virus fusion glycoprotein (GhV F)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8tvb
Q-score: 0.56
Wang Z, McCallum M, Yan L, Gibson CA, Sharkey W, Park YJ, Dang HV, Amaya M, Person A, Broder CC, Veesler D
PNAS (2024) 121 pp. e2314990121-e2314990121 [ Pubmed: 38593070 DOI: doi:10.1073/pnas.2314990121 ]
- Fusion glycoprotein f0,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (96 kDa, Protein from Thermotoga maritima MSB8)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Prefusion ghanian henipavirus f fused to the i53-50a trimer via an intervening 16 gs linker (Complex from Henipavirus ghanaense)
Langya Virus G glycoprotein (LayV G) with stabilizing mutations
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8tvi
Q-score: 0.552
Wang Z, McCallum M, Yan L, Gibson CA, Sharkey W, Park YJ, Dang HV, Amaya M, Person A, Broder CC, Veesler D
PNAS (2024) 121 pp. e2314990121-e2314990121 [ Pubmed: 38593070 DOI: doi:10.1073/pnas.2314990121 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Langya virus attachment glycoprotein g (68 kDa, Protein from Langya virus)
- Stabilized langya virus attachment glycoprotein layvg (Complex from Langya virus)
- Zinc ion (65 Da, Ligand)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7txz
Q-score: 0.518
Wang Z, Amaya M, Addetia A, Dang HV, Reggiano G, Yan L, Hickey AC, DiMaio F, Broder CC, Veesler D
Science (2022) 375 pp. 1373-1378 [ Pubmed: 35239409 DOI: doi:10.1126/science.abm5561 ]
- Glycoprotein g (60 kDa, Protein from Nipah henipavirus)
- Nipah virus attachment protein ectodomain in complex with nah1.3 neutralizing antibody fab fragment (Complex from Nipah henipavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nah1.3 fab light chain (23 kDa, Protein from Mus sp.)
- Nah1.3 fab heavy chain (50 kDa, Protein from Mus sp.)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7ty0
Q-score: 0.439
Wang Z, Amaya M, Addetia A, Dang HV, Reggiano G, Yan L, Hickey AC, DiMaio F, Broder CC, Veesler D
Science (2022) 375 pp. 1373-1378 [ Pubmed: 35239409 DOI: doi:10.1126/science.abm5561 ]
- Glycoprotein g (60 kDa, Protein from Nipah henipavirus)
- Nipah virus attachment protein ectodomain in complex with nah1.3 neutralizing antibody fab fragment (Complex from Nipah henipavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nah fab light chain (23 kDa, Protein from Mus sp.)
- Igh protein (50 kDa, Protein from Mus sp.)
Structure of the NiV F glycoprotein in complex with the 12B2 neutralizing antibody
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7ki4
Q-score: 0.537
Dang HV, Cross RW, Borisevich V, Bornholdt ZA, West BR, Chan YP, Mire CE, Da Silva SC, Dimitrov AS, Yan L, Amaya M, Navaratnarajah CK, Zeitlin L, Geisbert TW, Broder CC, Veesler D
Nat Struct Mol Biol (2021) 28 pp. 426-434 [ DOI: doi:10.1038/s41594-021-00584-8 Pubmed: 33927387 ]
- 12b2 fab light chain (23 kDa, Protein from Mus musculus)
- Niv f glycoprotein in complex with the 12b2 neutralizing antibody fab fragment (Complex from Nipah virus)
- 12b2 heavy chain (48 kDa, Protein from Mus musculus)
- Fusion glycoprotein f0 (60 kDa, Protein from Nipah virus)
Structure of the HeV F glycoprotein in complex with the 1F5 neutralizing antibody
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7ki6
Q-score: 0.575
Dang HV, Cross RW, Borisevich V, Bornholdt ZA, West BR, Chan YP, Mire CE, Da Silva SC, Dimitrov AS, Yan L, Amaya M, Navaratnarajah CK, Zeitlin L, Geisbert TW, Broder CC, Veesler D
Nat Struct Mol Biol (2021) 28 pp. 426-434 [ DOI: doi:10.1038/s41594-021-00584-8 Pubmed: 33927387 ]
- Fusion glycoprotein f0 (59 kDa, Protein from Hendra henipavirus)
- Hev f glycoprotein in complex with the 1f5 neutralizing antibody fab fragment (Complex from Hendra henipavirus)
- 1f5 fab light chain (23 kDa, Protein from Mus musculus)
- 1f5 heavy chain (49 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6tys
Q-score: 0.478
Dang HV, Chan YP, Park YJ, Snijder J, Da Silva SC, Vu B, Yan L, Feng YR, Rockx B, Geisbert TW, Mire CE, Broder CC, Veesler D
Nat Struct Mol Biol (2019) 26 pp. 980-987 [ Pubmed: 31570878 DOI: doi:10.1038/s41594-019-0308-9 ]
- 5b3 antibody light chain (11 kDa, Protein from Mus musculus)
- 5b3 antibody (Complex from Mus musculus)
- Fusion glycoprotein f0 (59 kDa, Protein from Nipah virus)
- 5b3 antibody heavy chain (13 kDa, Protein from Mus musculus)
- Nipah virus fusion (f) glycoprotein in complex with the 5b3 antibody fab fragment (Complex)
- Fusion glycoprotein f0 (Complex from Nipah virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)