Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9jm0
Q-score: 0.492
Wang Y, Wang C, Guan Z, Cao J, Xu J, Wang S, Cui Y, Wang Q, Chen Y, Yin Y, Zhang D, Liu H, Sun M, Jin S, Tao P, Zou T
Cell Rep (2024) 43 pp. 114857-114857 [ DOI: doi:10.1016/j.celrep.2024.114857 Pubmed: 39395169 ]
- Dna (85-mer) (26 kDa, DNA from Escherichia coli)
- Retron ec86 reverse transcriptase (37 kDa, Protein from Escherichia coli)
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
- Rna (82-mer) (26 kDa, RNA from Escherichia coli)
- Retron ec86 putative ribosyltransferase/dna-binding protein (35 kDa, Protein from Escherichia coli)
- Nicotinamide (122 Da, Ligand)
- Retron ec86-effector fiber (Complex from Escherichia coli)
- Rna (5'-r(p*cp*gp*up*ap*ap*gp*gp*gp*up*gp*cp*gp*cp*a)-3') (4 kDa, RNA from Escherichia coli)
Cryo-EM structure of human type I OSM receptor complex: model for full extracellular assembly
Resolution: 3.99 Å
EM Method: Single-particle
Fitted PDBs: 8v29
Q-score: 0.219
Zhou Y, Stevis PE, Cao J, Ehrlich G, Jones J, Rafique A, Sleeman MW, Olson WC, Franklin MC
Nat Commun (2024) 15 pp. 9776-9776 [ Pubmed: 39532904 DOI: doi:10.1038/s41467-024-54124-1 ]
- Interleukin-6 receptor subunit beta (71 kDa, Protein from Homo sapiens)
- Human osm in complex with gp130 and lifr (Complex)
- Leukemia inhibitory factor receptor (92 kDa, Protein from Homo sapiens)
- Oncostatin-m (22 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human type I OSM receptor complex: model for assembly core region
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8v2a
Q-score: 0.438
Zhou Y, Stevis PE, Cao J, Ehrlich G, Jones J, Rafique A, Sleeman MW, Olson WC, Franklin MC
Nat Commun (2024) 15 pp. 9776-9776 [ Pubmed: 39532904 DOI: doi:10.1038/s41467-024-54124-1 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Interleukin-6 receptor subunit beta (71 kDa, Protein from Homo sapiens)
- Leukemia inhibitory factor receptor (92 kDa, Protein from Homo sapiens)
- Human osm (Complex from Homo sapiens)
- Gp130 and lifr (Complex from Homo sapiens)
- Oncostatin-m (22 kDa, Protein from Homo sapiens)
- Human osm in complex with gp130 and lifr (Complex)
Cryo-EM structure of mouse type II OSM receptor complex: model for full extracellular assembly
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8v2b
Q-score: 0.31
Zhou Y, Stevis PE, Cao J, Ehrlich G, Jones J, Rafique A, Sleeman MW, Olson WC, Franklin MC
Nat Commun (2024) 15 pp. 9776-9776 [ Pubmed: 39532904 DOI: doi:10.1038/s41467-024-54124-1 ]
- Mouse osm in complex with gp130 and osmr (Complex)
- Interleukin-6 receptor subunit beta (70 kDa, Protein from Mus musculus)
- Oncostatin-m-specific receptor subunit beta (82 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Oncostatin-m (20 kDa, Protein from Mus musculus)
Cryo-EM structure of mouse type II OSM receptor complex: model for assembly core region
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 8v2c
Q-score: 0.479
Zhou Y, Stevis PE, Cao J, Ehrlich G, Jones J, Rafique A, Sleeman MW, Olson WC, Franklin MC
Nat Commun (2024) 15 pp. 9776-9776 [ Pubmed: 39532904 DOI: doi:10.1038/s41467-024-54124-1 ]
- Mouse osm in complex with gp130 and osmr (Complex)
- Interleukin-6 receptor subunit beta (70 kDa, Protein from Mus musculus)
- Oncostatin-m-specific receptor subunit beta (82 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Oncostatin-m (20 kDa, Protein from Mus musculus)
State 2 of SARS-CoV-2 XBB Variant Spike protein trimer complexed with antibody PW5-5
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Pw5-5 heavy chain (49 kDa, Protein from Homo sapiens)
- Sars spike protein (s) in complex with broadly neutralizing antibody pw5-5 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Pw5-5 light chain (23 kDa, Protein from Homo sapiens)
Structure of SARS-CoV Spike protein complexed with antibody PW5-5
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Sars spike protein (s) in complex with broadly neutralizing antibody pw5-5 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Pw5-5 light chain (23 kDa, Protein from Homo sapiens)
- Pw5-5 heavy chain (49 kDa, Protein from Homo sapiens)
- Spike glycoprotein (131 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
The local refined map of SARS-CoV-2 XBB Variant Spike protein complexed with antibody PW5-535
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Pw5-535 light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Xbb spike protein (s) in complex with broadly neutralizing antibody pw5-5353 (Complex from Homo sapiens)
- Pw5-535 heavy chain (49 kDa, Protein from Homo sapiens)
Trimer state of SARS-CoV Spike protein complexed with antibody PW5-535
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Pw5-535 light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (131 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars spike protein (s) in complex with broadly neutralizing antibody pw5-535 (Complex from Homo sapiens)
- Pw5-535 heavy chain (49 kDa, Protein from Homo sapiens)
The local refined map of SARS-CoV Spike protein complexed with antibody PW5-5
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Sars spike protein (s) in complex with broadly neutralizing antibody pw5-5 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Pw5-5 light chain (23 kDa, Protein from Homo sapiens)
- Pw5-5 heavy chain (49 kDa, Protein from Homo sapiens)
- Spike glycoprotein (131 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)