Cryo-EM structure of cortactin stabilized Arp2/3-complex nucleated actin branches
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8p94
Q-score: 0.452
Liu T, Cao L, Mladenov M, Jegou A, Way M, Moores CA
Nat Struct Mol Biol (2024) 31 pp. 801-809 [ Pubmed: 38267598 DOI: doi:10.1038/s41594-023-01205-2 ]
- Actin-related protein 2/3 complex subunit 4 (19 kDa, Protein from Homo sapiens)
- Mouse cortactin (Complex from Mus musculus)
- Porcine actin, cytoplasmic 1 (Complex from Sus scrofa)
- Mouse capping protein (Complex from Mus musculus)
- Human arp2/3 c1bc5l complex (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin-related protein 3 (47 kDa, Protein from Homo sapiens)
- Actin-related protein 2/3 complex subunit 5-like protein (16 kDa, Protein from Homo sapiens)
- Cortactin stabilizes arp2/3-complex nucleated actin branches with daughter filament capped (Complex from Homo sapiens)
- F-actin-capping protein subunit alpha-1 (32 kDa, Protein from Mus musculus)
- Actin, cytoplasmic 1 (41 kDa, Protein from Sus scrofa)
- Phalloidin (Complex from Amanita phalloides)
- Actin-related protein 2/3 complex subunit 3 (20 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Phalloidin (808 Da, Protein from Amanita phalloides)
- Actin-related protein 2 (44 kDa, Protein from Homo sapiens)
- Src substrate cortactin (61 kDa, Protein from Mus musculus)
- Actin-related protein 2/3 complex subunit 1b (41 kDa, Protein from Homo sapiens)
- Isoform 2 of f-actin-capping protein subunit beta (30 kDa, Protein from Mus musculus)
- Actin-related protein 2/3 complex subunit 2 (34 kDa, Protein from Homo sapiens)
SARS-COV-2 Spike RBDMACSp36 binding to mACE2
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7fdk
Q-score: 0.442
Sun S, Gu H, Cao L, Chen Q, Ye Q, Yang G, Li RT, Fan H, Deng YQ, Song X, Qi Y, Li M, Lan J, Feng R, Guo Y, Zhu N, Qin S, Wang L, Zhang YF, Zhou C, Zhao L, Chen Y, Shen M, Cui Y, Yang X, Wang X, Tan W, Wang H, Wang X, Qin CF
Nat Commun (2021) 12 pp. 5654-5654 [ Pubmed: 34580297 DOI: doi:10.1038/s41467-021-25903-x ]
- Spike protein s1 (24 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (71 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 spike rbdmacsp36-mace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
The cryo-EM structure of HAV bound to a neutralizing antibody-F4
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6jhq
Q-score: -0.029
Cao L, Liu P, Yang P, Gao Q, Li H, Sun Y, Zhu L, Lin J, Su D, Rao Z, Wang X
PLoS Biol (2019) 17 pp. e3000229-e3000229 [ DOI: doi:10.1371/journal.pbio.3000229 Pubmed: 31039149 ]
- Vp2 (24 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Vp3 (27 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Antibody-f4 (Complex from Mus musculus)
- Human hepatitis a virus hu/australia/hm175/1976 (Virus from Human hepatitis A virus Hu/Australia/HM175/1976)
- Vp1 (30 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Human hepatitis a virus hu/australia/hm175/1976 and antibody-f4 (Complex)
- Fab heavy chain (23 kDa, Protein from Mus musculus)
The cryo-EM structure of HAV bound to a neutralizing antibody-F6
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 6jhr
Q-score: 0.018
Cao L, Liu P, Yang P, Gao Q, Li H, Sun Y, Zhu L, Lin J, Su D, Rao Z, Wang X
PLoS Biol (2019) 17 pp. e3000229-e3000229 [ DOI: doi:10.1371/journal.pbio.3000229 Pubmed: 31039149 ]
- Vp2 (24 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Vp3 (27 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Fab heavy chain (24 kDa, Protein from Mus musculus)
- Antibody-f6 (Complex from Mus musculus)
- Vp1 (30 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Human hepatitis a virus and antibody-f6 (Complex)
- Human hepatitis a virus (Virus from Human hepatitis A virus)
The cryo-EM structure of HAV bound to a neutralizing antibody-F7
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 6jhs
Q-score: -0.015
Cao L, Liu P, Yang P, Gao Q, Li H, Sun Y, Zhu L, Lin J, Su D, Rao Z, Wang X
PLoS Biol (2019) 17 pp. e3000229-e3000229 [ DOI: doi:10.1371/journal.pbio.3000229 Pubmed: 31039149 ]
- Vp2 (24 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Fab heavy chain (23 kDa, Protein from Mus musculus)
- Human hepatitis a virus and antibody-f7 (Complex)
- Vp3 (27 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Vp1 (30 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Antibody-f7 (Complex from Mus musculus)
- Human hepatitis a virus (Virus from Human hepatitis A virus)
The cryo-EM structure of HAV bound to a neutralizing antibody-F9
Resolution: 3.79 Å
EM Method: Single-particle
Fitted PDBs: 6jht
Q-score: 0.207
Cao L, Liu P, Yang P, Gao Q, Li H, Sun Y, Zhu L, Lin J, Su D, Rao Z, Wang X
PLoS Biol (2019) 17 pp. e3000229-e3000229 [ DOI: doi:10.1371/journal.pbio.3000229 Pubmed: 31039149 ]
- Vp2 (24 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Fab heavy chain (23 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Human hepatitis a virus and antibody-f9 (Complex)
- Vp3 (27 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Fab light chain (23 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Vp1 (30 kDa, Protein from Human hepatitis A virus Hu/Australia/HM175/1976)
- Antibody-f9 (Complex from Mus musculus)
- Human hepatitis a virus (Virus from Human hepatitis A virus)