CryoEM map of de novo designed oligomeric protein C4-81
Edman NI, Phal A, Redler RL, Schlichthaerle T, Srivatsan SR, Ehnes DD, Etemadi A, An SJ, Favor A, Li Z, Praetorius F, Gordon M, Vincent T, Marchiano S, Blakely L, Lin C, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Zheng Y, Murry CE, Schweppe DK, Freedman BS, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D
Cell (2024) 187 pp. 3726-3740.e43 [ Pubmed: 38861993 DOI: doi:10.1016/j.cell.2024.05.025 ]
CryoEM map of designed oligomeric protein C4-71
Edman NI, Phal A, Redler RL, Schlichthaerle T, Srivatsan SR, Ehnes DD, Etemadi A, An SJ, Favor A, Li Z, Praetorius F, Gordon M, Vincent T, Marchiano S, Blakely L, Lin C, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Zheng Y, Murry CE, Schweppe DK, Freedman BS, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D
Cell (2024) 187 pp. 3726-3740.e43 [ Pubmed: 38861993 DOI: doi:10.1016/j.cell.2024.05.025 ]
Resolution: 5.18 Å
EM Method: Single-particle
Fitted PDBs: 7x6w
Q-score: 0.249
Sun Z, Cheng J, Bai Y, Cao L, Xie D, Deng F, Zhang X, Rao Z, Lou Z
Protein Cell (2023) 14 pp. 914-918 [ DOI: doi:10.1093/procel/pwad019 Pubmed: 37038326 ]
- Envelopment polyprotein (61 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Envelopment polyprotein (54 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Severe fever with thrombocytopenia syndrome virus (Virus from Severe fever with thrombocytopenia syndrome virus)
SARS-CoV-2 spike in complex with multivalent miniprotein inhibitor FUS231-P24 (3RBDs open)
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vogeli B, Kruger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetic A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale Jr M, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D
Sci Transl Med (2022) 14 pp. eabn1252-eabn1252 [ Pubmed: 35412328 DOI: doi:10.1126/scitranslmed.abn1252 ]
- Sars-cov-2 hexapro spike protein (Protein from Severe acute respiratory syndrome coronavirus 2)
- Multivalent miniprotein inhibitor fus231-p24 (Protein from Synthetic construct)
- Sars-cov-2 hexapro spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Multivalent miniprotein inhibitor fus231-p24 (Complex from Synthetic construct)
- Sars-cov-2 spike in complex with multivalent miniprotein inhibitor fus231-p24 (3rbds open) (Complex from Severe acute respiratory syndrome coronavirus 2)
HIV-1 Envelope Glycoprotein clone PC64M4C054.SOSIP.664 in complex with PCT64_13C Fab
Rantalainen K, Berndsen ZT, Murrell S, Cao L, Omorodion O, Torres JL, Wu M, Umotoy J, Copps J, Poignard P, Landais E, Paulson JC, Wilson IA, Ward AB
Cell Rep (2018) 23 pp. 3249-3261 [ Pubmed: 29898396 DOI: doi:10.1016/j.celrep.2018.05.046 ]
- Hiv-1 envelope glycoprotein clone pc64m4c054.sosip.664 in complex with pct64_13c fab (Complex from Human immunodeficiency virus 1)
- Immunoglobulin g pct64-13c fab, heavy chain (Protein from Homo sapiens)
- Immunoglobulin g pct64-13c fab, light chain (Protein from Homo sapiens)
- Hiv-1 envelope glycoprotein clone pc64m4c054.sosip.664 (Protein from Human immunodeficiency virus 1)
HIV-1 Envelope Glycoprotein clone PC64M4C054.SOSIP in complex with PCT64-35S Fab
Rantalainen K, Berndsen ZT, Murrell S, Cao L, Omorodion O, Torres JL, Wu M, Umotoy J, Copps J, Poignard P, Landais E, Paulson JC, Wilson IA, Ward AB
Cell Rep (2018) 23 pp. 3249-3261 [ Pubmed: 29898396 DOI: doi:10.1016/j.celrep.2018.05.046 ]
- Hiv-1 envelope glycoprotein clone pc64m4c054.sosip.664 in complex with pct64-35s fab (Complex from Homo sapiens)
- Immunoglobulin g pct64-35s fab, light chain (Protein from Homo sapiens)
- Hiv-1 envelope glycoprotein clone pc64m4c054.sosip.664 (Protein from Human immunodeficiency virus 1)
- Immunoglobulin g pct64-35s fab, heavy chain (Protein from Homo sapiens)