Raw data used to generate the structure of WT ACTG2 F-actin
Ceron RH, Báez-Cruz FA, Palmer NJ, Carman PJ, Boczkowska M, Heuckeroth RO, Ostap EM, Dominguez R
Sci Adv (2024) 10 [ DOI: 10.1126/sciadv.adn6615 Pubmed: 38820162 ]
Image sets:
Raw data used to generate the structure of R257C ACTG2 F-actin
Ceron RH, Báez-Cruz FA, Palmer NJ, Carman PJ, Boczkowska M, Heuckeroth RO, Ostap EM, Dominguez R
Sci Adv (2024) 10 [ DOI: 10.1126/sciadv.adn6615 Pubmed: 38820162 ]
Image sets:
Raw data used to generate the structure of R40C ACTG2 F-actin
Ceron RH, Báez-Cruz FA, Palmer NJ, Carman PJ, Boczkowska M, Heuckeroth RO, Ostap EM, Dominguez R
Sci Adv (2024) 10 [ DOI: 10.1126/sciadv.adn6615 Pubmed: 38820162 ]
Image sets:
Raw data used to generate the structure of cortactin bound to the Arp2/3 complex
Fregoso FE, Boczkowska M, Rebowski G, Carman PJ, van Eeuwen T, Dominguez R
Nat Commun (2023) 14 [ DOI: 10.1038/s41467-023-42229-y Pubmed: 37898612 ]
Image sets:
Cryo-EM Structure of Wildtype Smooth Muscle Gamma Actin (ACTG2)
Resolution: 2.45 Å
EM Method: Helical reconstruction
Fitted PDBs: 8v2o
Q-score: 0.589
Ceron RH, Baez-Cruz FA, Palmer NJ, Carman PJ, Boczkowska M, Heuckeroth RO, Ostap EM, Dominguez R
Sci Adv (2024) 10 pp. eadn6615-eadn6615 [ Pubmed: 38820162 DOI: doi:10.1126/sciadv.adn6615 ]
- Magnesium ion (24 Da, Ligand)
- Actg2 filament (Complex from Homo sapiens)
- Actin, gamma-enteric smooth muscle (41 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM Structure of Smooth Muscle Gamma Actin (ACTG2) Mutant R257C
Resolution: 2.72 Å
EM Method: Helical reconstruction
Fitted PDBs: 8v2z
Q-score: 0.571
Ceron RH, Baez-Cruz FA, Palmer NJ, Carman PJ, Boczkowska M, Heuckeroth RO, Ostap EM, Dominguez R
Sci Adv (2024) 10 pp. eadn6615-eadn6615 [ Pubmed: 38820162 DOI: doi:10.1126/sciadv.adn6615 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin, gamma-enteric smooth muscle (41 kDa, Protein from Homo sapiens)
- Actg2 r257c filament (Complex from Homo sapiens)
Smooth Muscle Gamma Actin (ACTG2) Filament Mutant R40C
Resolution: 2.54 Å
EM Method: Helical reconstruction
Fitted PDBs: 8v30
Q-score: 0.585
Ceron RH, Baez-Cruz FA, Palmer NJ, Carman PJ, Boczkowska M, Heuckeroth RO, Ostap EM, Dominguez R
Sci Adv (2024) 10 pp. eadn6615-eadn6615 [ Pubmed: 38820162 DOI: doi:10.1126/sciadv.adn6615 ]
- Magnesium ion (24 Da, Ligand)
- Phalloidin (808 Da, Protein from synthetic construct)
- Actin, gamma-enteric smooth muscle (41 kDa, Protein from Homo sapiens)
- Actg2 r40c filament (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Structure of full-length LexA bound to a RecA filament
Resolution: 2.93 Å
EM Method: Helical reconstruction
Fitted PDBs: 8trg
Q-score: 0.51
Cory MB, Li A, Hurley CM, Carman PJ, Pumroy RA, Hostetler ZM, Perez RM, Venkatesh Y, Li X, Gupta K, Petersson EJ, Kohli RM
Nat Struct Mol Biol (2024) 31 pp. 1522-1531 [ Pubmed: 38755298 DOI: doi:10.1038/s41594-024-01317-3 ]
- Lexa repressor (22 kDa, Protein from Escherichia coli)
- Reca* activated filament (Complex from Escherichia coli)
- Sos signal complex consisting of reca, ssdna, and lexa (480 kDa, Complex from Escherichia coli)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna (27-mer) (8 kDa, DNA from Escherichia coli)
- Protein reca (41 kDa, Protein from Escherichia coli)
- Lexa dimer (Complex from Escherichia coli)
Cryo-EM structure of Cortactin-bound to Arp2/3 complex
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8tah
Q-score: 0.514
Fregoso FE, Boczkowska M, Rebowski G, Carman PJ, van Eeuwen T, Dominguez R
Nat Commun (2023) 14 pp. 6894-6894 [ Pubmed: 37898612 DOI: doi:10.1038/s41467-023-42229-y ]
- Src substrate cortactin (8 kDa, Protein from Mus musculus)
- Cortactin nta bound to arp2/3 complex (223 kDa, Complex from Bos taurus)
- Actin-related protein 3 (47 kDa, Protein from Bos taurus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Actin-related protein 2/3 complex subunit 3 (20 kDa, Protein from Bos taurus)
- Actin-related protein 2 (44 kDa, Protein from Bos taurus)
- Actin-related protein 2/3 complex subunit 4 (19 kDa, Protein from Bos taurus)
- Actin-related protein 2/3 complex subunit 2 (34 kDa, Protein from Bos taurus)
- Actin-related protein 2/3 complex subunit 1a (41 kDa, Protein from Bos taurus)
- Actin-related protein 2/3 complex subunit 5 (16 kDa, Protein from Bos taurus)
Sheared F-actin raw data from Structures of the free and capped ends of the actin filament
Carman PJ, Barrie KR, Rebowski G, Dominguez R
Science (2023) 380 pp. 1287-1292 [ Pubmed: 37228182 DOI: 10.1126/science.adg6812 ]
Image sets:
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