SARS-CoV-2 Spike S2 bound to Fab 54043-5
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8vcr
Q-score: 0.535
Johnson NV, Wall SC, Kramer KJ, Holt CM, Periasamy S, Richardson SI, Manamela NP, Suryadevara N, Andreano E, Paciello I, Pierleoni G, Piccini G, Huang Y, Ge P, Allen JD, Uno N, Shiakolas AR, Pilewski KA, Nargi RS, Sutton RE, Abu-Shmais AA, Parks R, Haynes BF, Carnahan RH, Crowe Jr JE, Montomoli E, Rappuoli R, Bukreyev A, Ross TM, Sautto GA, McLellan JS, Georgiev IS
Structure (2024) 32 pp. 1893- [ DOI: doi:10.1016/j.str.2024.08.022 Pubmed: 39326419 ]
- Trimeric s2 bound to fab 54043-5 (Complex)
- 54043-5 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike protein s2 (65 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab 54043-5 (Complex from Homo sapiens)
- 54043-5 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S2 (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8tqi
Q-score: 0.499
Suryadevara N, Otrelo-Cardoso AR, Kose N, Hu YX, Binshtein E, Wolters RM, Greninger AL, Handal LS, Carnahan RH, Moscona A, Jardetzky TS, Crowe Jr JE
Nat Microbiol (2024) 9 pp. 2128-2143 [ Pubmed: 38858594 DOI: doi:10.1038/s41564-024-01722-w ]
- Hemagglutinin-neuraminidase glycoprotein (Complex from Human respirovirus 3)
- Light chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
- Light chain fab rpiv3-23 (23 kDa, Protein from Homo sapiens)
- Heavy chain fab rpiv3-23 (24 kDa, Protein from Homo sapiens)
- Hpiv3 hn in complex with rpiv3-23 and rpiv3-28 fabs (Complex from Human respirovirus 3)
- Recombinant rpiv3-28 fab (Complex from Homo sapiens)
- Hemagglutinin-neuraminidase (50 kDa, Protein from Human respirovirus 3)
- Recombinant rpiv3-23 fab (Complex from Homo sapiens)
- Heavy chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
Human parainfluenza virus type 3 prefusion F trimer in complex with rPIV3-18 Fab
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8tqk
Q-score: 0.451
Suryadevara N, Otrelo-Cardoso AR, Kose N, Hu YX, Binshtein E, Wolters RM, Greninger AL, Handal LS, Carnahan RH, Moscona A, Jardetzky TS, Crowe Jr JE
Nat Microbiol (2024) 9 pp. 2128-2143 [ Pubmed: 38858594 DOI: doi:10.1038/s41564-024-01722-w ]
- Hpiv3 prefusion f trimer in complex with rpiv3-18 fab (Complex from Human respirovirus 3)
- Fusion glycoprotein f0 (57 kDa, Protein from Human respirovirus 3)
- Rpiv3-18 light chain (Complex from Homo sapiens)
- Rpiv3-18 heavy chain (Complex from Homo sapiens)
- Heavy chain fab rpiv3-18 (23 kDa, Protein from Homo sapiens)
- Light chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
- Fusion glycoprotein f0 (Complex from Human respirovirus 3)
Cryo-EM map of SARS-CoV-2 Omicron BA.2 spike in complex with LLNL-199
Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW, Lillo AM, Sundaram S, Bloom JD, Diamond MS, Crowe Jr JE, Carnahan RH, Faissol DM
Nature (2024) 629 pp. 878-885 [ Pubmed: 38720086 DOI: doi:10.1038/s41586-024-07385-1 ]
Cryo-EM map of SARS-CoV-2 Omicron BA.2 spike in complex with 2130-1-0114-112
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8ekd
Q-score: 0.433
Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW, Lillo AM, Sundaram S, Bloom JD, Diamond MS, Crowe Jr JE, Carnahan RH, Faissol DM
Nature (2024) 629 pp. 878-885 [ DOI: doi:10.1038/s41586-024-07385-1 Pubmed: 38720086 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab llnl-199 hc (14 kDa, Protein from Homo sapiens)
- Fab llnl-199 lc (12 kDa, Protein from Homo sapiens)
- Sars cov2 omicron ba.2 rbd (Complex from Severe acute respiratory syndrome coronavirus)
- Sars cov2 omicron ba.2 rbd complex with fab llnl-199 (Complex)
- Fab llnl-199 (Complex from Homo sapiens)
- Spike protein s2' (20 kDa, Protein from Severe acute respiratory syndrome coronavirus)
SARS-CoV-2 spike in complex with Fab 71281-33
Wall SC, Suryadevara N, Kim C, Shiakolas AR, Holt CM, Irbe EB, Wasdin PT, Suresh YP, Binshtein E, Chen EC, Zost SJ, Canfield E, Crowe Jr JE, Thompson-Arildsen MA, Sheward DJ, Carnahan RH, Georgiev IS
Cell Rep Med (2023) 4 pp. 101267-101267 [ DOI: doi:10.1016/j.xcrm.2023.101267 Pubmed: 37935199 ]
SARS-CoV-2 spike in complex with Fab 71281-33 (2)
Wall SC, Suryadevara N, Kim C, Shiakolas AR, Holt CM, Irbe EB, Wasdin PT, Suresh YP, Binshtein E, Chen EC, Zost SJ, Canfield E, Crowe Jr JE, Thompson-Arildsen MA, Sheward DJ, Carnahan RH, Georgiev IS
Cell Rep Med (2023) 4 pp. 101267-101267 [ DOI: doi:10.1016/j.xcrm.2023.101267 Pubmed: 37935199 ]
RSV F trimer bound to RSV-199 Fab
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8dzw
Q-score: 0.569
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ Pubmed: 37516111 DOI: doi:10.1016/j.chom.2023.07.002 ]
- Rsv fusion protein complex with rsv-199 fab (Complex from Human respiratory syncytial virus A2)
- Rsv fusion protein (53 kDa, Protein from Human respiratory syncytial virus A2)
- Rsv-199 light chain protein (22 kDa, Protein from Homo sapiens)
- Rsv-199 heavy chain protein (24 kDa, Protein from Homo sapiens)
HMPV F monomer bound to RSV-199 Fab
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8e2u
Q-score: 0.457
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ DOI: doi:10.1016/j.chom.2023.07.002 Pubmed: 37516111 ]
- Rsv-199 light chain (22 kDa, Protein from Homo sapiens)
- Fusion glycoprotein f0 (47 kDa, Protein from Human metapneumovirus A)
- Mpv fusion protein complex with rsv-199 fab (Complex from Human metapneumovirus)
- Rsv-199 heavy chain (24 kDa, Protein from Homo sapiens)
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 8eay
Q-score: 0.403
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ Pubmed: 37516111 DOI: doi:10.1016/j.chom.2023.07.002 ]
- 4i3 light chain protein (11 kDa, Protein from Homo sapiens)
- 4i3 heavy chain protein (13 kDa, Protein from Homo sapiens)
- Fusion glycoprotein f0 (45 kDa, Protein from Human metapneumovirus A)
- Mpv fusion protein complex with 4i3 fab (Complex from Human metapneumovirus)