RSV F trimer bound to RSV-199 Fab
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8dzw
Q-score: 0.569
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ Pubmed: 37516111 DOI: doi:10.1016/j.chom.2023.07.002 ]
- Rsv-199 heavy chain protein (24 kDa, Protein from Homo sapiens)
- Rsv fusion protein complex with rsv-199 fab (Complex from Human respiratory syncytial virus A2)
- Rsv-199 light chain protein (22 kDa, Protein from Homo sapiens)
- Rsv fusion protein (53 kDa, Protein from Human respiratory syncytial virus A2)
HMPV F monomer bound to RSV-199 Fab
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8e2u
Q-score: 0.457
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ DOI: doi:10.1016/j.chom.2023.07.002 Pubmed: 37516111 ]
- Rsv-199 light chain (22 kDa, Protein from Homo sapiens)
- Fusion glycoprotein f0 (47 kDa, Protein from Human metapneumovirus A)
- Mpv fusion protein complex with rsv-199 fab (Complex from Human metapneumovirus)
- Rsv-199 heavy chain (24 kDa, Protein from Homo sapiens)
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 8eay
Q-score: 0.403
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ Pubmed: 37516111 DOI: doi:10.1016/j.chom.2023.07.002 ]
- Fusion glycoprotein f0 (45 kDa, Protein from Human metapneumovirus A)
- Mpv fusion protein complex with 4i3 fab (Complex from Human metapneumovirus)
- 4i3 light chain protein (11 kDa, Protein from Homo sapiens)
- 4i3 heavy chain protein (13 kDa, Protein from Homo sapiens)
HMPV F dimer bound to RSV-199 Fab
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8ebp
Q-score: 0.426
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ DOI: doi:10.1016/j.chom.2023.07.002 Pubmed: 37516111 ]
- Fusion glycoprotein f0 (47 kDa, Protein from Human metapneumovirus A)
- Rsv-199 heavy chain protein (24 kDa, Protein from Homo sapiens)
- Mpv fusion protein complex with rsv-199 fab (Complex from Human metapneumovirus)
- Rsv-199 light chain protein (22 kDa, Protein from Homo sapiens)
CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7sfu
Q-score: 0.332
Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS
J Exp Med (2022) 219 [ DOI: doi:10.1084/jem.20212532 Pubmed: 35297953 ]
- Venezuelan equine encephalitis virus (strain tc-83) (Virus from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e2 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Capsid protein (18 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein e1 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7sfv
Q-score: 0.324
Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS
J Exp Med (2022) 219 [ DOI: doi:10.1084/jem.20212532 Pubmed: 35297953 ]
- Hveev-63 fab light chain (22 kDa, Protein from Homo sapiens)
- Venezuelan equine encephalitis virus (strain tc-83) (Virus from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e2 (46 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hveev-63 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Capsid protein (17 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7sfw
Q-score: 0.508
Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS
J Exp Med (2022) 219 [ DOI: doi:10.1084/jem.20212532 Pubmed: 35297953 ]
- Hveev-63 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Venezuelan equine encephalitis virus (strain tc-83) (Virus from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e2 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Capsid protein (30 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e1 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Hveev-63 fab light chain (11 kDa, Protein from Homo sapiens)
Motion corrected micrographs - purified SINV/EEEV particles and recombinant anti-EEEV Fab (EEEV-143)
Williamson LE, Gilliland T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe JE
Cell (2020) 183 pp. 1884-1.9e+26 [ Pubmed: 33301709 DOI: 10.1016/j.cell.2020.11.011 ]
Image sets:
Motion corrected micrographs - purified SINV/EEEV particles and recombinant anti-EEEV Fab (EEEV-33)
Williamson LE, Gilliland T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe JE
Cell (2020) 183 pp. 1884-1900.e23 [ Pubmed: 33301709 DOI: 10.1016/j.cell.2020.11.011 ]
Image sets:
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-143 Antibody
Williamson LE, Gilliland Jr T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe Jr JE
Cell (2020) 183 pp. 1884-1900.e23 [ Pubmed: 33301709 DOI: doi:10.1016/j.cell.2020.11.011 ]