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primary_citation_author:"Carpenter EP" AND author_name:"Dong YY" AND author_name:"Arrowsmith CH"
Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with HIP-B
Release date: March 16, 2022
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 7nsg
Q-score: 0.539
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 7nsg
Q-score: 0.539
Baronina A, Pike ACW, Yu X, Dong YY, Shintre CA, Tessitore A, Chu A, Rotty B, Venkaya S, Mukhopadhyay SMM, Borkowska O, Chalk R, Shrestha L, Burgess-Brown NA, Edwards AM, Arrowsmith CH, Bountra C, Han S, Carpenter EP
To Be Published
Sample:
- (-)-3-hydroxy-4,5,6,6a-tetrahydro-3ah-pyrrolo[3,4-d]isoxazole-6-carboxylic acid (172 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Excitatory amino acid transporter 3 (53 kDa, Protein from Homo sapiens)
- (+)-3-hydroxy-4,5,6,6a-tetrahydro-3ah-pyrrolo[3,4-d]isoxazole-6-carboxylic acid (172 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Ternary complex of excitatory amino acid transporter 3 with inhibitor hip-b (160 kDa, Complex from Homo sapiens)