Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 7ram
Q-score: 0.452
Liu J, Vanarsdall A, Chen DH, Chin A, Johnson D, Jardetzky TS
Mbio (2021) 12 pp. e0262521-e0262521 [ DOI: doi:10.1128/mBio.02625-21 Pubmed: 34700375 ]
- Human platelet-derived growth factor receptor alpha extracellular domain (Complex from Homo sapiens)
- Envelope glycoprotein l (27 kDa, Protein from Human herpesvirus 5 strain AD169)
- Hcmv trimer in complex with receptor pdgfralpha (Complex from Human herpesvirus 5 strain AD169)
- Envelope glycoprotein h (80 kDa, Protein from Human herpesvirus 5 strain AD169)
- Platelet-derived growth factor receptor alpha (59 kDa, Protein from Homo sapiens)
- Envelope glycoprotein o (53 kDa, Protein from Human betaherpesvirus 5)
Structure of HIV-1 reverse transcriptase initiation complex core
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7kjv
Q-score: 0.564
Ha B, Larsen KP, Zhang J, Fu Z, Montabana E, Jackson LN, Chen DH, Puglisi EV
Nat Commun (2021) 12 pp. 2500-2500 [ Pubmed: 33947853 DOI: doi:10.1038/s41467-021-22628-9 ]
- Trna lysine 3 fragment with gnra tetraloop (12 kDa, Macromolecule from Homo sapiens)
- Hiv-1 viral rna fragment (8 kDa, RNA from Human immunodeficiency virus 1)
- Hiv-1 reverse transcriptase initiation complex core (138 kDa, Complex from Human immunodeficiency virus 1)
- Reverse transcriptase/ribonuclease h (64 kDa, Protein from Human immunodeficiency virus type 1 group M subtype B (isolate BH10))
- Reverse transcriptase p51 subunit (51 kDa, Protein from Human immunodeficiency virus 1)
- Magnesium ion (24 Da, Ligand)
- Octyl beta-d-glucopyranoside (292 Da, Ligand)
Structure of HIV-1 reverse transcriptase initiation complex core with efavirenz
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7kjw
Q-score: 0.55
Ha B, Larsen KP, Zhang J, Fu Z, Montabana E, Jackson LN, Chen DH, Puglisi EV
Nat Commun (2021) 12 pp. 2500-2500 [ Pubmed: 33947853 DOI: doi:10.1038/s41467-021-22628-9 ]
- Hiv-1 reverse transcriptase initiation complex core with efavirenz (138 kDa, Complex from Human immunodeficiency virus 1)
- (-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2h-3,1-benzoxazin-2-one (315 Da, Ligand)
- Reverse transcriptase p51 subunit (51 kDa, Protein from Human immunodeficiency virus 1)
- Magnesium ion (24 Da, Ligand)
- Reverse transcriptase/ribonuclease h (64 kDa, Protein from Human immunodeficiency virus type 1 group M subtype B (isolate BH10))
- Hiv-1 viral rna fragment (8 kDa, RNA from Human immunodeficiency virus 1)
- Trna lysine 3 fragment with gnra tetraloop (12 kDa, Macromolecule from Homo sapiens)
Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7kjx
Q-score: 0.515
Ha B, Larsen KP, Zhang J, Fu Z, Montabana E, Jackson LN, Chen DH, Puglisi EV
Nat Commun (2021) 12 pp. 2500-2500 [ Pubmed: 33947853 DOI: doi:10.1038/s41467-021-22628-9 ]
- Trna lysine 3 fragment with gnra tetraloop (7 kDa, Macromolecule from Homo sapiens)
- Hiv-1 viral rna fragment (8 kDa, RNA from Human immunodeficiency virus 1)
- Hiv-1 reverse transcriptase initiation complex core with nevirapine (138 kDa, Complex from Human immunodeficiency virus 1)
- Reverse transcriptase/ribonuclease h (64 kDa, Protein from Human immunodeficiency virus type 1 group M subtype B (isolate BH10))
- Reverse transcriptase p51 subunit (51 kDa, Protein from Human immunodeficiency virus 1)
- Magnesium ion (24 Da, Ligand)
- 11-cyclopropyl-5,11-dihydro-4-methyl-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one (266 Da, Ligand)
Head-Middle module of Mediator
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6xp5
Q-score: 0.337
Zhang H, Chen DH, Mattoo RUH, Bushnell DA, Wang Y, Yuan C, Wang L, Wang C, Davis RE, Nie Y, Kornberg RD
Mol Cell (2021) 81 pp. 1781-1788.e4 [ Pubmed: 33571424 DOI: doi:10.1016/j.molcel.2021.01.022 ]
- Mediator of rna polymerase ii transcription subunit 6 (36 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Mediator of rna polymerase ii transcription subunit 14 (133 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Head-middle module of mediator (Complex from Chaetomium thermophilum)
- Mediator of rna polymerase ii transcription subunit 17 (69 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Mediator of rna polymerase ii transcription subunit 7 (27 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Heat (17 kDa, Protein from Chaetomium thermophilum)
- Mediator of rna polymerase ii transcription subunit 1 (81 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Mediator of rna polymerase ii transcription subunit 21 (15 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Unknown peptide (1 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Mediator of rna polymerase ii transcription subunit 4 (37 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Mediator of rna polymerase ii transcription subunit 9 (18 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Mediator of rna polymerase ii transcription subunit 11 (25 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Mediator of rna polymerase ii transcription subunit 31 (14 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Mediator of rna polymerase ii transcription subunit 8 (32 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Med22 (18 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Mediator of rna polymerase ii transcription subunit 18 (38 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7jmn
Q-score: 0.466
Zhang H, Chen DH, Mattoo RUH, Bushnell DA, Wang Y, Yuan C, Wang L, Wang C, Davis RE, Nie Y, Kornberg RD
Mol Cell (2021) 81 pp. 1781-1788.e4 [ Pubmed: 33571424 DOI: doi:10.1016/j.molcel.2021.01.022 ]
- Mediator of rna polymerase ii transcription subunit 5 (118 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Unknown peptide (4 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mediator of rna polymerase ii transcription subunit 14 (133 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Med15 (175 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- T module complex (Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mediator of rna polymerase ii transcription subunit 16 (123 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
Zhang H, Chen DH, Mattoo RUH, Bushnell DA, Wang Y, Yuan C, Wang L, Wang C, Davis RE, Nie Y, Kornberg RD
Mol Cell (2021) 81 pp. 1781-1788.e4 [ Pubmed: 33571424 DOI: doi:10.1016/j.molcel.2021.01.022 ]
The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion
Oliver SL, Xing Y, Chen DH, Roh SH, Pintilie GD, Bushnell DA, Sommer MH, Yang E, Carfi A, Chiu W, Arvin AM
PLoS Pathog (2021) 17 pp. e1008961-e1008961 [ DOI: doi:10.1371/journal.ppat.1008961 Pubmed: 33411789 ]
- Monoclonal antibody 93k bound to varicella-zoster virus glycoprotein b (Complex)
- Monoclonal antibody 93k bound to varicella-zoster virus glycoprotein b (Macromolecule from Human alphaherpesvirus 3)
- Monoclonal antibody 93k (Complex from unidentified)
- Varicella-zoster virus glycoprotein b (Complex from Human alphaherpesvirus 3)
The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion
Oliver SL, Xing Y, Chen DH, Roh SH, Pintilie GD, Bushnell DA, Sommer MH, Yang E, Carfi A, Chiu W, Arvin AM
PLoS Pathog (2021) 17 pp. e1008961-e1008961 [ DOI: doi:10.1371/journal.ppat.1008961 Pubmed: 33411789 ]
- Varicella-zoster virus glycoprotein b (Complex from Human alphaherpesvirus 3)
- Monoclonal antibody sg2 bound to varicella-zoster virus glycoprotein b (Protein from Human alphaherpesvirus 3)
- Monoclonal antibody sg2 (Complex from unidentified)
- Monoclonal antibody sg2 bound to varicella-zoster virus glycoprotein b (Complex)
The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7k1s
Q-score: 0.394
Oliver SL, Xing Y, Chen DH, Roh SH, Pintilie GD, Bushnell DA, Sommer MH, Yang E, Carfi A, Chiu W, Arvin AM
PLoS Pathog (2021) 17 pp. e1008961-e1008961 [ DOI: doi:10.1371/journal.ppat.1008961 Pubmed: 33411789 ]