Cryo-EM structure of CMKLR1 signaling complex
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8sg1
Q-score: 0.546
Zhang X, Weiss T, Cheng MH, Chen S, Ambrosius CK, Czerniak AS, Li K, Feng M, Bahar I, Beck-Sickinger AG, Zhang C
PLoS Biol (2023) 21 pp. e3002188-e3002188 [ DOI: doi:10.1371/journal.pbio.3002188 Pubmed: 38055679 ]
- Palmitic acid (256 Da, Ligand)
- Chemerin-like receptor 1 (33 kDa, Protein from Homo sapiens)
- Scfv16 (28 kDa, Protein from Mus musculus)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Chemerin 9 (1 kDa, Protein from Homo sapiens)
- Chemerin9-cmklr1-gi complex (Complex from Spodoptera frugiperda)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (36 kDa, Protein from Homo sapiens)
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8thr
Q-score: 0.401
Dalton MP, Cheng MH, Bahar I, Coleman JA
eLife (2024) 12 [ DOI: doi:10.7554/eLife.91973 Pubmed: 38517752 ]
- (3s,5r,11bs)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a]isoquinolin-2-one (317 Da, Ligand)
- Fluorescent protein mvenus,synaptic vesicular amine transporter,gfp nano body,synaptic vesicular amine transporter,synaptic vesicular amine transporter (93 kDa, Protein from Vicugna pacos)
- Human vmat2 complexed with tetrabenazine (93 kDa, Complex from Homo sapiens)
Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with VH domain F6
Chen C, Saville JW, Marti MM, Schafer A, Cheng MH, Mannar D, Zhu X, Berezuk AM, Banerjee A, Sobolewski MD, Kim A, Treat BR, Da Silva Castanha PM, Enick N, McCormick KD, Liu X, Adams C, Hines MG, Sun Z, Chen W, Jacobs JL, Barratt-Boyes SM, Mellors JW, Baric RS, Bahar I, Dimitrov DS, Subramaniam S, Martinez DR, Li W
iScience (2022) 25 pp. 104798-104798 [ DOI: doi:10.1016/j.isci.2022.104798 Pubmed: 35875685 ]
- Sars-cov-2 beta (b.1.351) spike protein (Protein from Severe acute respiratory syndrome coronavirus 2)
- Vh f6 (Complex from Homo sapiens)
- Sars-cov-2 beta (b.1.351) spike protein in complex with vh domain f6 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 beta (b.1.351) spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Vh f6 (Protein from Homo sapiens)
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8di5
Q-score: 0.51
Chen C, Saville JW, Marti MM, Schafer A, Cheng MH, Mannar D, Zhu X, Berezuk AM, Banerjee A, Sobolewski MD, Kim A, Treat BR, Da Silva Castanha PM, Enick N, McCormick KD, Liu X, Adams C, Hines MG, Sun Z, Chen W, Jacobs JL, Barratt-Boyes SM, Mellors JW, Baric RS, Bahar I, Dimitrov DS, Subramaniam S, Martinez DR, Li W
iScience (2022) 25 pp. 104798-104798 [ DOI: doi:10.1016/j.isci.2022.104798 Pubmed: 35875685 ]
- Vh f6 (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Vh f6 (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 beta (b.1.351) spike protein in complex with vh domain f6 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 beta (b.1.351) spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)