Cryo-EM structure of MPXV M2 in complex with human B7.1
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8hxa
Q-score: 0.52
Yang S, Wang Y, Yu F, Cheng R, Zhang Y, Zhou D, Ren X, Deng Z, Zhao H
Nat Commun (2023) 14 pp. 5186-5186 [ Pubmed: 37626059 DOI: doi:10.1038/s41467-023-40748-2 ]
- M2-hb7.1 (Complex from Homo sapiens)
- Nfkb inhibitor (23 kDa, Protein from Monkeypox virus)
- T-lymphocyte activation antigen cd80 (22 kDa, Protein from Homo sapiens)
Cryo-EM structure of MPXV M2 hexamer in complex with human B7.2
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8hxb
Q-score: 0.516
Yang S, Wang Y, Yu F, Cheng R, Zhang Y, Zhou D, Ren X, Deng Z, Zhao H
Nat Commun (2023) 14 pp. 5186-5186 [ Pubmed: 37626059 DOI: doi:10.1038/s41467-023-40748-2 ]
- Nfkb inhibitor (23 kDa, Protein from Monkeypox virus)
- T-lymphocyte activation antigen cd86 (24 kDa, Protein from Homo sapiens)
- M2-hb7.2 (Complex from Homo sapiens)
Cryo-EM structure of MPXV M2 heptamer in complex with human B7.2
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8hxc
Q-score: 0.45
Yang S, Wang Y, Yu F, Cheng R, Zhang Y, Zhou D, Ren X, Deng Z, Zhao H
Nat Commun (2023) 14 pp. 5186-5186 [ Pubmed: 37626059 DOI: doi:10.1038/s41467-023-40748-2 ]
- Nfkb inhibitor (23 kDa, Protein from Monkeypox virus)
- T-lymphocyte activation antigen cd86 (24 kDa, Protein from Homo sapiens)
- M2-hb7.2 (Complex from Homo sapiens)
Apo human Kv3.1 cryo-EM structure
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 7pqt
Q-score: 0.574
Botte M, Huber S, Bucher D, Klint JK, Rodriguez D, Tagmose L, Chami M, Cheng R, Hennig M, Abdul Rahman W
Pnas Nexus (2022) 1 pp. pgac083-pgac083 [ Pubmed: 36741467 DOI: doi:10.1093/pnasnexus/pgac083 ]
- Potassium voltage-gated channel subfamily c member 1 (58 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Water (18 Da, Ligand)
- Detergent solubilized tetramer of human kv3.1 potassium ion channel (Complex from Homo sapiens)
Ligand-bound human Kv3.1 cryo-EM structure (Lu AG00563)
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 7pqu
Q-score: 0.52
Botte M, Huber S, Bucher D, Klint JK, Rodriguez D, Tagmose L, Chami M, Cheng R, Hennig M, Abdul Rahman W
Pnas Nexus (2022) 1 pp. pgac083-pgac083 [ Pubmed: 36741467 DOI: doi:10.1093/pnasnexus/pgac083 ]
- Detergent solubilized tetramer of human kv3.1 potassium ion channel in complex with lu ag00563 (Complex from Homo sapiens)
- Potassium voltage-gated channel subfamily c member 1 (58 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 1-(4-methylphenyl)sulfonyl-n-(1,3-oxazol-2-ylmethyl)pyrrole-3-carboxamide (345 Da, Ligand)
- Water (18 Da, Ligand)