Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Enterovirus a71 mature virion in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Fab h1a6.2 (Complex from Mus)
Cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- Capsid protein vp4 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Capsid protein vp1 (7 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 mature virion in complex with fab h1a6.2 (Complex)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of coxsackievirus A16 A-particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- Coxsackievirus a16 a-particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement)
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- The fab of h1a6.2 (Complex from Mus musculus)
- Genome polyprotein (26 kDa, Protein from Coxsackievirus A16)
- Genome polyprotein (27 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- The heavy chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- The light chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
Cryo-EM structure of enterovirus A71 mature virion
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 8A10 (CVB1-A:8A10)
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 7x35
Q-score: 0.557
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279-1294.e6 [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 8a10 light chain (11 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- 8a10 heavy chain (13 kDa, Protein from Mus musculus)
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3)
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 7x3y
Q-score: 0.557
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279-1294.e6 [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- 9a3 light chain (11 kDa, Protein from Mus musculus)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 9a3 heavy chain (13 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Cryo-em structure of coxsackievirus b1 empty particle in complex with nab 9a3 (cvb1-e:9a3) (Complex from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 2E6 (CVB1-E:2E6)
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7x2g
Q-score: 0.515
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 2e6 light chain (11 kDa, Protein from Mus musculus)
- Cryo-em structure of coxsackievirus b1 empty particle in complex with nab 2e6 (cvb1-e:2e6) (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of Coxsackievirus B1 pre-A particle in complex with nAb 2E6 (CVB1-pre-A:2E6)
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 7x2i
Q-score: 0.537
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of coxsackievirus b1 pre-a particle in complex with nab 2e6 (cvb1-pre-a:2e6) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 2e6 light chain (11 kDa, Protein from Mus musculus)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)