Cryo-EM structure of Chikungunya virus asymmetric unit
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8fcg
Q-score: 0.518
Chmielewski D, Su GC, Kaelber JT, Pintilie GD, Chen M, Jin J, Auguste AJ, Chiu W
Pnas Nexus (2024) 3 pp. pgae102-pgae102 [ Pubmed: 38525304 DOI: doi:10.1093/pnasnexus/pgae102 ]
- E2 glycoprotein (47 kDa, Protein from Chikungunya virus)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Chikungunya virus (500 kDa, Virus from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8u26
Q-score: 0.572
Nat Methods (2024) 21 pp. 37-40 [ DOI: doi:10.1038/s41592-023-02082-9 Pubmed: 37973972 ]
- Nanobody 35 (15 kDa, Protein from Lama glama)
- Substance p bound to active human neurokinin 1 receptor in complex with minigs399 (141 kDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
- Protachykinin-1 (1 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Substance-p receptor (47 kDa, Protein from Homo sapiens)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8u28
Q-score: 0.464
Nat Methods (2024) 21 pp. 37-40 [ DOI: doi:10.1038/s41592-023-02082-9 Pubmed: 37973972 ]
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8u2c
Q-score: 0.534
Nat Methods (2024) 21 pp. 37-40 [ DOI: doi:10.1038/s41592-023-02082-9 Pubmed: 37973972 ]
- Inhibitor-bound abcg2 (Complex from Homo sapiens)
- Fab heavy chain constant domain (22 kDa, Protein from Homo sapiens)
- 5d3 fab light chain variable domain (23 kDa, Protein from Mus musculus)
- Broad substrate specificity atp-binding cassette transporter abcg2 (72 kDa, Protein from Homo sapiens)
- 5d3 fab heavy chain variable domain (23 kDa, Protein from Mus musculus)
- Fab light chain constant domain (22 kDa, Protein from Homo sapiens)
The symmetry-released subpellicular microtubule map from detergent-extracted Toxoplasma cells
Resolution: 8.4 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7tnq
Q-score: 0.076
Sun SY, Segev-Zarko LA, Chen M, Pintilie GD, Schmid MF, Ludtke SJ, Boothroyd JC, Chiu W
PNAS (2022) 119 [ Pubmed: 35121661 DOI: doi:10.1073/pnas.2111661119 ]
- Microtubule associated protein spm1 (38 kDa, Protein from Toxoplasma gondii)
- Tubulin beta chain (50 kDa, Protein from Toxoplasma gondii)
- Tubulin alpha chain (50 kDa, Protein from Toxoplasma gondii)
- Microtubule complex of tubulin and intra-luminal proteins (Cellular component from Toxoplasma gondii)
- Pdi family protein (24 kDa, Protein from Toxoplasma gondii)
- Pdi family protein (21 kDa, Protein from Toxoplasma gondii)
Subpellicular microtubule from detergent-extract Toxoplasma gondii cells
Resolution: 6.7 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7tns
Q-score: 0.118
Sun SY, Segev-Zarko LA, Chen M, Pintilie GD, Schmid MF, Ludtke SJ, Boothroyd JC, Chiu W
PNAS (2022) 119 [ Pubmed: 35121661 DOI: doi:10.1073/pnas.2111661119 ]
- Microtubule associated protein spm1 (38 kDa, Protein from Toxoplasma gondii)
- Microtubule complex of alpha-tubulin and beta-tubulin with intra-lumenal proteins (Cellular component from Toxoplasma gondii)
- Tubulin beta chain (50 kDa, Protein from Toxoplasma gondii)
- Tubulin alpha chain (50 kDa, Protein from Toxoplasma gondii)
- Pdi family protein (24 kDa, Protein from Toxoplasma gondii)
- Pdi family protein (21 kDa, Protein from Toxoplasma gondii)
The tubulin-based conoid from detergent-extract Toxoplasma gondii cells
Resolution: 9.3 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7tnt
Q-score: 0.053
Sun SY, Segev-Zarko LA, Chen M, Pintilie GD, Schmid MF, Ludtke SJ, Boothroyd JC, Chiu W
PNAS (2022) 119 [ Pubmed: 35121661 DOI: doi:10.1073/pnas.2111661119 ]
- Tubulin beta chain (47 kDa, Protein from Toxoplasma gondii)
- Tubulin alpha chain (48 kDa, Protein from Toxoplasma gondii)
- A conoid complex of tubulin with other protein components (Cellular component from Toxoplasma gondii)