TRiC-substrate complex in ATP/AlFx closed state
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7lum
Q-score: 0.291
Knowlton JJ, Gestaut D, Ma B, Taylor G, Seven AB, Leitner A, Wilson GJ, Shanker S, Yates NA, Prasad BVV, Aebersold R, Chiu W, Frydman J, Dermody TS
PNAS (2021) 118 [ Pubmed: 33836586 DOI: doi:10.1073/pnas.2018127118 ]
- Human tric/cct complex (1 MDa, Complex from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
Human TRiC/CCT complex with reovirus outer capsid protein sigma-3
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 7lup
Q-score: 0.217
Knowlton JJ, Gestaut D, Ma B, Taylor G, Seven AB, Leitner A, Wilson GJ, Shanker S, Yates NA, Prasad BVV, Aebersold R, Chiu W, Frydman J, Dermody TS
PNAS (2021) 118 [ Pubmed: 33836586 DOI: doi:10.1073/pnas.2018127118 ]
- Human tric/cct complex with reovirus outer capsid protein sigma-3 (41 MDa, Complex)
- Zinc ion (65 Da, Ligand)
- Reovirus outer capsid protein sigma-3 (Complex from Mammalian orthoreovirus 3 Dearing)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- Outer capsid protein sigma-3 (41 kDa, Protein from Reovirus type 3 (strain Dearing))
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- Human tric/cct complex (Complex from Homo sapiens)
- Water (18 Da, Ligand)
Resolution: 7.8 Å
EM Method: Single-particle
Fitted PDBs: 6nr8
Q-score: 0.137
Gestaut D, Roh SH, Ma B, Pintilie G, Joachimiak LA, Leitner A, Walzthoeni T, Aebersold R, Chiu W, Frydman J
Cell (2019) 177 pp. 751-765.e15 [ DOI: doi:10.1016/j.cell.2019.03.012 Pubmed: 30955883 ]
- T-complex protein 1 subunit theta (56 kDa, Protein from Homo sapiens)
- Prefoldin subunit 2 (11 kDa, Protein from Homo sapiens)
- Prefoldin subunit 3 (15 kDa, Protein from Homo sapiens)
- Prefoldin subunit 1 (12 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (58 kDa, Protein from Homo sapiens)
- Prefoldin subunit 5 (14 kDa, Protein from Homo sapiens)
- Htric-hpfd (Complex from Homo sapiens)
- Prefoldin subunit 4 (12 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (55 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (57 kDa, Protein from Homo sapiens)
- Hpfd (Complex from Homo sapiens)
- T-complex protein 1 subunit eta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (54 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (56 kDa, Protein from Homo sapiens)
- Htric (Complex from Homo sapiens)
- Prefoldin subunit 6 (11 kDa, Protein from Homo sapiens)
Resolution: 8.5 Å
EM Method: Single-particle
Fitted PDBs: 6nr9
Q-score: 0.111
Gestaut D, Roh SH, Ma B, Pintilie G, Joachimiak LA, Leitner A, Walzthoeni T, Aebersold R, Chiu W, Frydman J
Cell (2019) 177 pp. 751-765.e15 [ DOI: doi:10.1016/j.cell.2019.03.012 Pubmed: 30955883 ]
- T-complex protein 1 subunit theta (56 kDa, Protein from Homo sapiens)
- Prefoldin subunit 2 (11 kDa, Protein from Homo sapiens)
- Prefoldin subunit 3 (15 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (58 kDa, Protein from Homo sapiens)
- Prefoldin subunit 1 (12 kDa, Protein from Homo sapiens)
- Prefoldin subunit 5 (14 kDa, Protein from Homo sapiens)
- Htric-hpfd (Complex from Homo sapiens)
- T-complex protein 1 subunit delta (55 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (56 kDa, Protein from Homo sapiens)
- Prefoldin subunit 4 (12 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (57 kDa, Protein from Homo sapiens)
- Hpfd (Complex from Homo sapiens)
- T-complex protein 1 subunit eta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (54 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (56 kDa, Protein from Homo sapiens)
- Htric (Complex from Homo sapiens)
- Prefoldin subunit 6 (11 kDa, Protein from Homo sapiens)
Resolution: 7.7 Å
EM Method: Single-particle
Fitted PDBs: 6nra
Q-score: 0.101
Gestaut D, Roh SH, Ma B, Pintilie G, Joachimiak LA, Leitner A, Walzthoeni T, Aebersold R, Chiu W, Frydman J
Cell (2019) 177 pp. 751-765.e15 [ DOI: doi:10.1016/j.cell.2019.03.012 Pubmed: 30955883 ]
- T-complex protein 1 subunit theta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (58 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (55 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (54 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (56 kDa, Protein from Homo sapiens)
- Htric (Complex from Homo sapiens)
Resolution: 8.7 Å
EM Method: Single-particle
Fitted PDBs: 6nrb
Q-score: 0.109
Gestaut D, Roh SH, Ma B, Pintilie G, Joachimiak LA, Leitner A, Walzthoeni T, Aebersold R, Chiu W, Frydman J
Cell (2019) 177 pp. 751-765.e15 [ DOI: doi:10.1016/j.cell.2019.03.012 Pubmed: 30955883 ]
- T-complex protein 1 subunit theta (56 kDa, Protein from Homo sapiens)
- Prefoldin subunit 2 (11 kDa, Protein from Homo sapiens)
- Prefoldin subunit 3 (15 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (58 kDa, Protein from Homo sapiens)
- Prefoldin subunit 1 (12 kDa, Protein from Homo sapiens)
- Prefoldin subunit 5 (14 kDa, Protein from Homo sapiens)
- Htric-hpfd (Complex from Homo sapiens)
- T-complex protein 1 subunit delta (55 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (56 kDa, Protein from Homo sapiens)
- Prefoldin subunit 4 (12 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (57 kDa, Protein from Homo sapiens)
- Hpfd (Complex from Homo sapiens)
- T-complex protein 1 subunit eta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (54 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (56 kDa, Protein from Homo sapiens)
- Htric (Complex from Homo sapiens)
- Prefoldin subunit 6 (11 kDa, Protein from Homo sapiens)
Resolution: 8.3 Å
EM Method: Single-particle
Fitted PDBs: 6nrc
Q-score: 0.112
Gestaut D, Roh SH, Ma B, Pintilie G, Joachimiak LA, Leitner A, Walzthoeni T, Aebersold R, Chiu W, Frydman J
Cell (2019) 177 pp. 751-765.e15 [ DOI: doi:10.1016/j.cell.2019.03.012 Pubmed: 30955883 ]
- T-complex protein 1 subunit theta (56 kDa, Protein from Homo sapiens)
- Prefoldin subunit 2 (11 kDa, Protein from Homo sapiens)
- Prefoldin subunit 3 (15 kDa, Protein from Homo sapiens)
- Prefoldin subunit 1 (12 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (58 kDa, Protein from Homo sapiens)
- Prefoldin subunit 5 (14 kDa, Protein from Homo sapiens)
- Htric-hpfd (Complex from Homo sapiens)
- Prefoldin subunit 4 (12 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (55 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (57 kDa, Protein from Homo sapiens)
- Hpfd (Complex from Homo sapiens)
- T-complex protein 1 subunit eta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (54 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (56 kDa, Protein from Homo sapiens)
- Htric (Complex from Homo sapiens)
- Prefoldin subunit 6 (11 kDa, Protein from Homo sapiens)
Resolution: 8.2 Å
EM Method: Single-particle
Fitted PDBs: 6nrd
Q-score: 0.111
Gestaut D, Roh SH, Ma B, Pintilie G, Joachimiak LA, Leitner A, Walzthoeni T, Aebersold R, Chiu W, Frydman J
Cell (2019) 177 pp. 751-765.e15 [ DOI: doi:10.1016/j.cell.2019.03.012 Pubmed: 30955883 ]
- T-complex protein 1 subunit theta (56 kDa, Protein from Homo sapiens)
- Prefoldin subunit 2 (11 kDa, Protein from Homo sapiens)
- Prefoldin subunit 3 (15 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (58 kDa, Protein from Homo sapiens)
- Prefoldin subunit 1 (12 kDa, Protein from Homo sapiens)
- Prefoldin subunit 5 (14 kDa, Protein from Homo sapiens)
- Htric-hpfd (Complex from Homo sapiens)
- T-complex protein 1 subunit delta (55 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (56 kDa, Protein from Homo sapiens)
- Prefoldin subunit 4 (12 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (57 kDa, Protein from Homo sapiens)
- Hpfd (Complex from Homo sapiens)
- T-complex protein 1 subunit eta (56 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (54 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (56 kDa, Protein from Homo sapiens)
- Htric (Complex from Homo sapiens)
- Prefoldin subunit 6 (11 kDa, Protein from Homo sapiens)