Cryo-EM structure of Chikungunya virus asymmetric unit
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8fcg
Q-score: 0.518
Chmielewski D, Su GC, Kaelber JT, Pintilie GD, Chen M, Jin J, Auguste AJ, Chiu W
Pnas Nexus (2024) 3 pp. pgae102-pgae102 [ Pubmed: 38525304 DOI: doi:10.1093/pnasnexus/pgae102 ]
- E2 glycoprotein (47 kDa, Protein from Chikungunya virus)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Chikungunya virus (500 kDa, Virus from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
The symmetry-released subpellicular microtubule map from detergent-extracted Toxoplasma cells
Resolution: 8.4 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7tnq
Q-score: 0.076
Sun SY, Segev-Zarko LA, Chen M, Pintilie GD, Schmid MF, Ludtke SJ, Boothroyd JC, Chiu W
PNAS (2022) 119 [ Pubmed: 35121661 DOI: doi:10.1073/pnas.2111661119 ]
- Microtubule associated protein spm1 (38 kDa, Protein from Toxoplasma gondii)
- Tubulin beta chain (50 kDa, Protein from Toxoplasma gondii)
- Tubulin alpha chain (50 kDa, Protein from Toxoplasma gondii)
- Microtubule complex of tubulin and intra-luminal proteins (Cellular component from Toxoplasma gondii)
- Pdi family protein (24 kDa, Protein from Toxoplasma gondii)
- Pdi family protein (21 kDa, Protein from Toxoplasma gondii)
Subpellicular microtubule from detergent-extract Toxoplasma gondii cells
Resolution: 6.7 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7tns
Q-score: 0.118
Sun SY, Segev-Zarko LA, Chen M, Pintilie GD, Schmid MF, Ludtke SJ, Boothroyd JC, Chiu W
PNAS (2022) 119 [ Pubmed: 35121661 DOI: doi:10.1073/pnas.2111661119 ]
- Microtubule associated protein spm1 (38 kDa, Protein from Toxoplasma gondii)
- Microtubule complex of alpha-tubulin and beta-tubulin with intra-lumenal proteins (Cellular component from Toxoplasma gondii)
- Tubulin beta chain (50 kDa, Protein from Toxoplasma gondii)
- Tubulin alpha chain (50 kDa, Protein from Toxoplasma gondii)
- Pdi family protein (24 kDa, Protein from Toxoplasma gondii)
- Pdi family protein (21 kDa, Protein from Toxoplasma gondii)
The tubulin-based conoid from detergent-extract Toxoplasma gondii cells
Resolution: 9.3 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7tnt
Q-score: 0.053
Sun SY, Segev-Zarko LA, Chen M, Pintilie GD, Schmid MF, Ludtke SJ, Boothroyd JC, Chiu W
PNAS (2022) 119 [ Pubmed: 35121661 DOI: doi:10.1073/pnas.2111661119 ]
- Tubulin beta chain (47 kDa, Protein from Toxoplasma gondii)
- Tubulin alpha chain (48 kDa, Protein from Toxoplasma gondii)
- A conoid complex of tubulin with other protein components (Cellular component from Toxoplasma gondii)
TRiC-substrate complex in ATP/AlFx closed state
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7lum
Q-score: 0.291
Knowlton JJ, Gestaut D, Ma B, Taylor G, Seven AB, Leitner A, Wilson GJ, Shanker S, Yates NA, Prasad BVV, Aebersold R, Chiu W, Frydman J, Dermody TS
PNAS (2021) 118 [ Pubmed: 33836586 DOI: doi:10.1073/pnas.2018127118 ]
- Human tric/cct complex (1 MDa, Complex from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
Human TRiC/CCT complex with reovirus outer capsid protein sigma-3
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 7lup
Q-score: 0.217
Knowlton JJ, Gestaut D, Ma B, Taylor G, Seven AB, Leitner A, Wilson GJ, Shanker S, Yates NA, Prasad BVV, Aebersold R, Chiu W, Frydman J, Dermody TS
PNAS (2021) 118 [ Pubmed: 33836586 DOI: doi:10.1073/pnas.2018127118 ]
- Human tric/cct complex with reovirus outer capsid protein sigma-3 (41 MDa, Complex)
- Zinc ion (65 Da, Ligand)
- Reovirus outer capsid protein sigma-3 (Complex from Mammalian orthoreovirus 3 Dearing)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- Outer capsid protein sigma-3 (41 kDa, Protein from Reovirus type 3 (strain Dearing))
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- Human tric/cct complex (Complex from Homo sapiens)
- Water (18 Da, Ligand)
Type I-F CRISPR-Csy complex with its inhibitor AcrF9
Resolution: 2.57 Å
EM Method: Single-particle
Fitted PDBs: 6vqv
Q-score: 0.495
Zhang K, Wang S, Li S, Zhu Y, Pintilie GD, Mou TC, Schmid MF, Huang Z, Chiu W
PNAS (2020) 117 pp. 7176-7182 [ DOI: doi:10.1073/pnas.1922638117 Pubmed: 32170016 ]
- Crispr-associated endonuclease cas6/csy4 (21 kDa, Protein from Pseudomonas aeruginosa)
- Acrf9 (7 kDa, Protein from Pseudomonas aeruginosa)
- Crispr-associated protein csy1 (49 kDa, Protein from Pseudomonas aeruginosa)
- Type i-f crispr-csy complex with its inhibitor acrf9 (350 kDa, Complex from Pseudomonas aeruginosa)
- Crrna (60-mer) (19 kDa, RNA from Pseudomonas aeruginosa)
- Crispr-associated protein csy3 (39 kDa, Protein from Pseudomonas aeruginosa)
- Crispr-associated protein csy2 (36 kDa, Protein from Pseudomonas aeruginosa)
Type I-F CRISPR-Csy complex with its inhibitor AcrF8
Resolution: 3.42 Å
EM Method: Single-particle
Fitted PDBs: 6vqw
Q-score: 0.462
Zhang K, Wang S, Li S, Zhu Y, Pintilie GD, Mou TC, Schmid MF, Huang Z, Chiu W
PNAS (2020) 117 pp. 7176-7182 [ DOI: doi:10.1073/pnas.1922638117 Pubmed: 32170016 ]
- Crispr-associated endonuclease cas6/csy4 (21 kDa, Protein from Pseudomonas aeruginosa)
- Acrf8 (10 kDa, Protein from Pseudomonas aeruginosa)
- Type i-f crispr-csy complex with its inhibitor acrf8 (350 kDa, Complex from Pseudomonas aeruginosa)
- Crispr-associated protein csy1 (49 kDa, Protein from Pseudomonas aeruginosa)
- Crrna (40-mer) (19 kDa, RNA from Pseudomonas aeruginosa)
- Crispr-associated protein csy3 (39 kDa, Protein from Pseudomonas aeruginosa)
- Type i-f crispr-associated protein csy2 (36 kDa, Protein from Pseudomonas aeruginosa)
Type I-F CRISPR-Csy complex with its inhibitor AcrF6
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 6vqx
Q-score: 0.433
Zhang K, Wang S, Li S, Zhu Y, Pintilie GD, Mou TC, Schmid MF, Huang Z, Chiu W
PNAS (2020) 117 pp. 7176-7182 [ DOI: doi:10.1073/pnas.1922638117 Pubmed: 32170016 ]
- Crispr-associated endonuclease cas6/csy4 (21 kDa, Protein from Pseudomonas aeruginosa)
- Crispr-associated protein csy3 (39 kDa, Protein from Pseudomonas aeruginosa)
- Crispr-associated protein csy1 (49 kDa, Protein from Pseudomonas aeruginosa)
- Type i-f crispr-csy complex with its inhibitor acrf6 (350 kDa, Complex from Pseudomonas aeruginosa)
- Crrna (60-mer) (19 kDa, RNA from Pseudomonas aeruginosa)
- Acrf6 (10 kDa, Protein from Pseudomonas aeruginosa)
- Type i-f crispr-associated protein csy2 (36 kDa, Protein from Pseudomonas aeruginosa)
Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 1 (OA-1)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6nyf
Q-score: 0.437
Zhang K, Zhang H, Li S, Pintilie GD, Mou TC, Gao Y, Zhang Q, van den Bedem H, Schmid MF, Au SWN, Chiu W
PNAS (2019) 116 pp. 6800-6805 [ DOI: doi:10.1073/pnas.1821959116 Pubmed: 30894496 ]