Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 9are
Q-score: 0.362
Chou TH, Epstein M, Fritzemeier RG, Akins NS, Paladugu S, Ullman EZ, Liotta DC, Traynelis SF, Furukawa H
Nature (2024) 632 pp. 209-217 [ Pubmed: 39085540 DOI: doi:10.1038/s41586-024-07742-0 ]
- Di-heterotetrameric glun1-glun2b nmda receptors (400 kDa, Complex from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 9arf
Q-score: 0.473
Chou TH, Epstein M, Fritzemeier RG, Akins NS, Paladugu S, Ullman EZ, Liotta DC, Traynelis SF, Furukawa H
Nature (2024) 632 pp. 209-217 [ Pubmed: 39085540 DOI: doi:10.1038/s41586-024-07742-0 ]
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rat glun1-glu2b di-heterotetrameric nmda receptor channel (400 kDa, Complex from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)
Rat GluN1-GluN2B NMDA receptor channel in apo conformation
Resolution: 4.05 Å
EM Method: Single-particle
Fitted PDBs: 9arg
Q-score: 0.292
Chou TH, Epstein M, Fritzemeier RG, Akins NS, Paladugu S, Ullman EZ, Liotta DC, Traynelis SF, Furukawa H
Nature (2024) 632 pp. 209-217 [ Pubmed: 39085540 DOI: doi:10.1038/s41586-024-07742-0 ]
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Di-heterotetrameric glun1-glun2b nmda receptors (400 kDa, Complex from Rattus norvegicus)
Rat GluN1-GluN2B NMDA receptor channel in complex with glycine
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 9arh
Q-score: 0.419
Chou TH, Epstein M, Fritzemeier RG, Akins NS, Paladugu S, Ullman EZ, Liotta DC, Traynelis SF, Furukawa H
Nature (2024) 632 pp. 209-217 [ Pubmed: 39085540 DOI: doi:10.1038/s41586-024-07742-0 ]
- Di-heterotetrameric glun1-glun2b nmda receptors (400 kDa, Complex from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- Isoform b of glutamate receptor ionotropic, nmda 1 (108 kDa, Protein from Rattus norvegicus)
- Glycine (75 Da, Ligand)
Rat GluN1-GluN2B NMDA receptor channel in complex with glutamate
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 9ari
Q-score: 0.342
Chou TH, Epstein M, Fritzemeier RG, Akins NS, Paladugu S, Ullman EZ, Liotta DC, Traynelis SF, Furukawa H
Nature (2024) 632 pp. 209-217 [ Pubmed: 39085540 DOI: doi:10.1038/s41586-024-07742-0 ]
- Glutamic acid (147 Da, Ligand)
- Di-heterotetrameric glun1-glun2b nmda receptors (400 kDa, Complex from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- Isoform b of glutamate receptor ionotropic, nmda 1 (108 kDa, Protein from Rattus norvegicus)
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 9bib
Q-score: 0.341
Chou TH, Epstein M, Fritzemeier RG, Akins NS, Paladugu S, Ullman EZ, Liotta DC, Traynelis SF, Furukawa H
Nature (2024) 632 pp. 209-217 [ Pubmed: 39085540 DOI: doi:10.1038/s41586-024-07742-0 ]
- Di-heterotetrameric glun1-glun2b nmda receptors (400 kDa, Complex from Rattus norvegicus)
- Glutamate receptor (98 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 7saa
Q-score: 0.505
Chou TH, Epstein M, Michalski K, Fine E, Biggin PC, Furukawa H
Nat Struct Mol Biol (2022) 29 pp. 507-518 [ Pubmed: 35637422 DOI: doi:10.1038/s41594-022-00772-0 ]
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)
- Hetero-tetrameric glun1a-glun2b nmda receptors (Complex from Rattus norvegicus)
Phencyclidine-bound GluN1a-GluN2B NMDA receptors
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7sab
Q-score: 0.364
Chou TH, Epstein M, Michalski K, Fine E, Biggin PC, Furukawa H
Nat Struct Mol Biol (2022) 29 pp. 507-518 [ Pubmed: 35637422 DOI: doi:10.1038/s41594-022-00772-0 ]
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Hetero-tetrameric glun1a-glun2b nmdar receptors (Complex from Rattus norvegicus)
- 1-(phenyl-1-cyclohexyl)piperidine (243 Da, Ligand)
S-(+)-ketamine bound GluN1a-GluN2B NMDA receptors at 3.69 Angstrom resolution
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7sac
Q-score: 0.419
Chou TH, Epstein M, Michalski K, Fine E, Biggin PC, Furukawa H
Nat Struct Mol Biol (2022) 29 pp. 507-518 [ Pubmed: 35637422 DOI: doi:10.1038/s41594-022-00772-0 ]
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- (2~{s})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one (237 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)
- Hetero-tetrameric glun1a-glun2b nmda receptors (Complex from Rattus norvegicus)
Memantine-bound GluN1a-GluN2B NMDA receptors
Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 7sad
Q-score: 0.376
Chou TH, Epstein M, Michalski K, Fine E, Biggin PC, Furukawa H
Nat Struct Mol Biol (2022) 29 pp. 507-518 [ Pubmed: 35637422 DOI: doi:10.1038/s41594-022-00772-0 ]
- Glutamate receptor ionotropic, nmda 2b (98 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Memantine (179 Da, Ligand)
- Hetero-tetrameric glun1a-glun2b nmda receptors (Complex from Rattus norvegicus)