High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1
Resolution: 4.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 7u0z
Q-score: 0.41
Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
Cell (2022) 185 pp. 1346-1355.e15 [ Pubmed: 35247328 DOI: doi:10.1016/j.cell.2022.02.026 ]
TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 7u10
Q-score: 0.403
Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
Cell (2022) 185 pp. 1346-1355.e15 [ Pubmed: 35247328 DOI: doi:10.1016/j.cell.2022.02.026 ]
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 7u11
Q-score: 0.431
Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
Cell (2022) 185 pp. 1346-1355.e15 [ Pubmed: 35247328 DOI: doi:10.1016/j.cell.2022.02.026 ]
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 7u12
Q-score: 0.282
Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
Cell (2022) 185 pp. 1346-1355.e15 [ Pubmed: 35247328 DOI: doi:10.1016/j.cell.2022.02.026 ]
Resolution: 2.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 7u13
Q-score: 0.265
Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
Cell (2022) 185 pp. 1346-1355.e15 [ Pubmed: 35247328 DOI: doi:10.1016/j.cell.2022.02.026 ]
Resolution: 4.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 7u14
Q-score: 0.283
Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
Cell (2022) 185 pp. 1346-1355.e15 [ Pubmed: 35247328 DOI: doi:10.1016/j.cell.2022.02.026 ]
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 7u15
Q-score: 0.428
Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
Cell (2022) 185 pp. 1346-1355.e15 [ Pubmed: 35247328 DOI: doi:10.1016/j.cell.2022.02.026 ]
Resolution: 2.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 7u16
Q-score: 0.495
Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
Cell (2022) 185 pp. 1346-1355.e15 [ Pubmed: 35247328 DOI: doi:10.1016/j.cell.2022.02.026 ]
Doublet Tau Fibril from Corticobasal Degeneration Human Brain Tissue
Resolution: 3.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 6vh7
Q-score: 0.376
Arakhamia T, Lee CE, Carlomagno Y, Duong DM, Kundinger SR, Wang K, Williams D, DeTure M, Dickson DW, Cook CN, Seyfried NT, Petrucelli L, Fitzpatrick AWP
Cell (2020) 180 pp. 633-644.e12 [ DOI: doi:10.1016/j.cell.2020.01.027 Pubmed: 32032505 ]
Singlet Tau Fibril from Corticobasal Degeneration Human Brain Tissue
Resolution: 4.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 6vha
Q-score: 0.28
Arakhamia T, Lee CE, Carlomagno Y, Duong DM, Kundinger SR, Wang K, Williams D, DeTure M, Dickson DW, Cook CN, Seyfried NT, Petrucelli L, Fitzpatrick AWP
Cell (2020) 180 pp. 633-644.e12 [ DOI: doi:10.1016/j.cell.2020.01.027 Pubmed: 32032505 ]