Cryo-EM structure of Arf1-decorated membrane tubules
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8s5c
Q-score: 0.508
Haupt C, Semchonok DA, Stubbs MT, Bacia K, Desfosses A
To Be Published
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Adp-ribosylation factor 1 (20 kDa, Protein from Saccharomyces cerevisiae)
- Arf1 coated membrane tubules (Complex from Saccharomyces cerevisiae)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
Cryo-EM structure of Arf1-decorated membrane tubules
Resolution: 3.79 Å
EM Method: Helical reconstruction
Fitted PDBs: 8s5d
Q-score: 0.302
Haupt C, Semchonok DA, Stubbs MT, Bacia K, Desfosses A
To Be Published
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Adp-ribosylation factor 1 (20 kDa, Protein from Saccharomyces cerevisiae)
- Arf1 coated membrane tubules (Complex from Saccharomyces cerevisiae)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
Cryo-EM structure of Arf1-decorated membrane tubules
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8s5e
Q-score: 0.569
Haupt C, Semchonok DA, Stubbs MT, Bacia K, Desfosses A
Cell Structure (2024)
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Adp-ribosylation factor 1 (20 kDa, Protein from Saccharomyces cerevisiae)
- Heptameric complex of arf1 with gsp and mg (Complex from Saccharomyces cerevisiae)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
Cryo-EM reconstruction of TNKS2 SAM-PARP filament
Pillay N, Mariotti L, Zaleska M, Inian O, Jessop M, Hibbs S, Desfosses A, Hopkins P.C.R, Templeton C.M, Beuron F, Morris E.P, Guettler S
To Be Published
Image sets:
- Unaligned multi-frame micrographs of TNKS2 SAM-PARP filament - Dataset 2
- Unaligned multi-frame micrographs of TNKS2 SAM-PARP filament - Dataset 1
- Unaligned multi-frame micrographs of TNKS2 SAM-PARP filament - Dataset 5
- Unaligned multi-frame micrographs of TNKS2 SAM-PARP filament - Dataset 4
- Unaligned multi-frame micrographs of TNKS2 SAM-PARP filament - Dataset 3
Cryo-EM structure of human tankyrase 2 SAM-PARP filament (G1032W mutant)
Resolution: 2.98 Å
EM Method: Helical reconstruction
Fitted PDBs: 8aly
Q-score: 0.586
Pillay N, Mariotti L, Zaleska M, Inian O, Jessop M, Hibbs S, Desfosses A, Hopkins PCR, Templeton CM, Beuron F, Morris EP, Guettler S
Nature (2022) 612 pp. 162-169 [ Pubmed: 36418402 DOI: doi:10.1038/s41586-022-05449-8 ]
- Poly [adp-ribose] polymerase tankyrase-2 (34 kDa, Protein from Homo sapiens)
- Tnks2 sam-parp (867-1162) filament (34 MDa, Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
Helical reconstruction of BCL10 CARD and MALT1 DEATH DOMAIN complex
Resolution: 4.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 6gk2
Q-score: 0.3
Schlauderer F, Seeholzer T, Desfosses A, Gehring T, Strauss M, Hopfner KP, Gutsche I, Krappmann D, Lammens K
Nat Commun (2018) 9 pp. 4041-4041 [ Pubmed: 30279415 DOI: doi:10.1038/s41467-018-06573-8 ]
- Complex of bcl10 card and malt1 death domain (104 MDa, Complex from Homo sapiens)
- B-cell lymphoma/leukemia 10 (12 kDa, Protein from Homo sapiens)
- Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (10 kDa, Protein from Homo sapiens)
Cryo-EM structure of Plasmodium falciparum actin I
Vahokoski J, Bhargav SP, Desfosses A, Andreadaki M, Kumpula E, Ignatev A, Martinez SM, Lepper S, Frischknecht F, Siden-Kiamos I, Sachse C, Kursula I
PLoS Pathog (2014) 10 pp. e1004091- [ Pubmed: 24743229 DOI: doi:10.1371/journal.ppat.1004091 ]