Gag CA-SP1 immature lattice from intact enveloped virus-like particles
Resolution: 2.42 Å
EM Method: Single-particle
Fitted PDBs: 9cwv
Q-score: 0.581
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
- Inositol hexakisphosphate (660 Da, Ligand)
- Human immunodeficiency virus type 1 group m subtype b (isolate ny5) (hiv-1) (Virus from Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1))
- Water (18 Da, Ligand)
- Gag (25 kDa, Protein from Human immunodeficiency virus type 1 group M subtype B (isolate HXB2))
Gag CA-SP1 immature lattice bound with Lenacapavir and Bevirimat from enveloped virus like particles
Resolution: 2.1 Å
EM Method: Single-particle
Fitted PDBs: 9d6c
Q-score: 0.612
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
- Inositol hexakisphosphate (660 Da, Ligand)
- 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid (584 Da, Ligand)
- Water (18 Da, Ligand)
- Human immunodeficiency virus type 1 (new york-5 isolate) (Virus from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- Gag (25 kDa, Protein from Human immunodeficiency virus type 1 group M subtype B (isolate HXB2))
- Lenacapavir (968 Da, Ligand)
Gag CA-SP1 immature lattice bound with Lenacapavir from enveloped virus like particles
Resolution: 2.18 Å
EM Method: Single-particle
Fitted PDBs: 9d6d
Q-score: 0.587
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
- Gag polyprotein (25 kDa, Protein from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- Water (18 Da, Ligand)
- Inositol hexakisphosphate (660 Da, Ligand)
- Human immunodeficiency virus type 1 (new york-5 isolate) (Virus from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- Lenacapavir (968 Da, Ligand)
Gag CA-SP1 immature lattice bound with Bevirimat from enveloped virus like particles
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 9d6e
Q-score: 0.467
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
- Gag polyprotein (25 kDa, Protein from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- Inositol hexakisphosphate (660 Da, Ligand)
- Human immunodeficiency virus type 1 (new york-5 isolate) (Virus from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid (584 Da, Ligand)
Gag CA-SP1 immature lattice from enveloped and perforated virus like particles
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 9d88
Q-score: 0.474
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
Gag CA-SP1 immature lattice bound with Lenacapavir from enveloped virus like particles (T8I)
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 9dwd
Q-score: 0.501
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y
bioRxiv (2024) [ DOI: doi:10.1101/2024.10.09.617473 Pubmed: 39416065 ]
- Gag (25 kDa, Protein from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- Lenacapavir (968 Da, Ligand)
- Human immunodeficiency virus type 1 (new york-5 isolate) (Virus from Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE))
- Inositol hexakisphosphate (660 Da, Ligand)