Structure of nucleotide-free Pediculus humanus (Ph) PINK1 dimer
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 8uyf
Q-score: 0.56
Gan ZY, Callegari S, Nguyen TN, Kirk NS, Leis A, Lazarou M, Dewson G, Komander D
Sci Adv (2024) 10 pp. eadj7408-eadj7408 [ DOI: doi:10.1126/sciadv.adj7408 Pubmed: 38241364 ]
Structure of AMP-PNP-bound Pediculus humanus (Ph) PINK1 dimer
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8uyh
Q-score: 0.548
Gan ZY, Callegari S, Nguyen TN, Kirk NS, Leis A, Lazarou M, Dewson G, Komander D
Sci Adv (2024) 10 pp. eadj7408-eadj7408 [ DOI: doi:10.1126/sciadv.adj7408 Pubmed: 38241364 ]
- Serine/threonine-protein kinase pink1, mitochondrial (53 kDa, Protein from Pediculus humanus corporis)
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Amp-pnp-bound pediculus humanus (ph) pink1 dodecamer (Complex from Pediculus humanus corporis)
Structure of ADP-bound and phosphorylated Pediculus humanus (Ph) PINK1 dimer
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8uyi
Q-score: 0.504
Gan ZY, Callegari S, Nguyen TN, Kirk NS, Leis A, Lazarou M, Dewson G, Komander D
Sci Adv (2024) 10 pp. eadj7408-eadj7408 [ DOI: doi:10.1126/sciadv.adj7408 Pubmed: 38241364 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adp-bound and phosphorylated pediculus humanus (ph) pink1 dodecamer (Complex from Pediculus humanus corporis)
- Serine/threonine-protein kinase pink1, mitochondrial (53 kDa, Protein from Pediculus humanus corporis)
- Magnesium ion (24 Da, Ligand)
Structure of dimeric phosphorylated Pediculus humanus (Ph) PINK1
Gan ZY, Callegari S, Cobbold SA, Cotton TR, Mlodzianoski MJ, Schubert AF, Geoghegan ND, Rogers KL, Leis A, Dewson G, Glukhova A, Komander D
Nature (2021) [ Pubmed: 34933320 DOI: doi:10.1038/s41586-021-04340-2 ]
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7t4k
Q-score: 0.506
Gan ZY, Callegari S, Cobbold SA, Cotton TR, Mlodzianoski MJ, Schubert AF, Geoghegan ND, Rogers KL, Leis A, Dewson G, Glukhova A, Komander D
Nature (2022) 602 pp. 328-335 [ Pubmed: 34933320 DOI: doi:10.1038/s41586-021-04340-2 ]
Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 7t4l
Q-score: 0.489
Gan ZY, Callegari S, Cobbold SA, Cotton TR, Mlodzianoski MJ, Schubert AF, Geoghegan ND, Rogers KL, Leis A, Dewson G, Glukhova A, Komander D
Nature (2022) 602 pp. 328-335 [ Pubmed: 34933320 DOI: doi:10.1038/s41586-021-04340-2 ]
Structure of dodecameric unphosphorylated Pediculus humanus (Ph) PINK1 D357A mutant
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 7t4m
Q-score: 0.607
Gan ZY, Callegari S, Cobbold SA, Cotton TR, Mlodzianoski MJ, Schubert AF, Geoghegan ND, Rogers KL, Leis A, Dewson G, Glukhova A, Komander D
Nature (2022) 602 pp. 328-335 [ Pubmed: 34933320 DOI: doi:10.1038/s41586-021-04340-2 ]
Structure of dimeric unphosphorylated Pediculus humanus (Ph) PINK1 D357A mutant
Resolution: 2.35 Å
EM Method: Single-particle
Fitted PDBs: 7t4n
Q-score: 0.648
Gan ZY, Callegari S, Cobbold SA, Cotton TR, Mlodzianoski MJ, Schubert AF, Geoghegan ND, Rogers KL, Leis A, Dewson G, Glukhova A, Komander D
Nature (2022) 602 pp. 328-335 [ Pubmed: 34933320 DOI: doi:10.1038/s41586-021-04340-2 ]