Cryo-EM structure of Tdk1-Bdf1 complex
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9ja5
Q-score: 0.524
Cryo-EM structure of CB1-beta-arrestin1 complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8wu1
Q-score: 0.473
Liao YY, Zhang H, Shen Q, Cai C, Ding Y, Shen DD, Guo J, Qin J, Dong Y, Zhang Y, Li XM
Cell (2023) 186 pp. 5784-5797.e17 [ DOI: doi:10.1016/j.cell.2023.11.017 Pubmed: 38101408 ]
- Cannabinoid receptor 1,vasopressin v2 receptor (50 kDa, Protein from Homo sapiens)
- Beta-arrestin-1 (44 kDa, Protein from Bos taurus)
- Fab30 heavy chain (25 kDa, Protein from Homo sapiens)
- Cryo-em structure of human cannabinoid receptor 1 with effector protein (Complex from Bos taurus)
- Methyl n-{1-[(4-fluorophenyl)methyl]-1h-indazole-3-carbonyl}-3-methyl-l-valinate (397 Da, Ligand)
- Fab30 light chain (23 kDa, Protein from Homo sapiens)
Structural insights into human brain gut peptide cholecystokinin receptors
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8ia7
Q-score: 0.522
Ding Y, Zhang H, Liao YY, Chen LN, Ji SY, Qin J, Mao C, Shen DD, Lin L, Wang H, Zhang Y, Li XM
Cell Discov (2022) 8 pp. 55-55 [ DOI: doi:10.1038/s41421-022-00420-3 Pubmed: 35672283 ]
- Gastrin/cholecystokinin type b receptor (48 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- G subunit q (gi1-gq chimeric) (Complex from Homo sapiens)
- Cck-8 (1 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
- Human brain gut peptide cholecystokinin receptors (Complex)
- Cck-8 (Complex)
- Scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Cholecystokinin receptor (Complex from Homo sapiens)
- Scfv16 (28 kDa, Protein from Mus musculus)
Structural insights into human brain gut peptide cholecystokinin receptors
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7xou
Q-score: 0.434
Ding Y, Zhang H, Liao YY, Chen LN, Ji SY, Qin J, Mao C, Shen DD, Lin L, Wang H, Zhang Y, Li XM
Cell Discov (2022) 8 pp. 55-55 [ Pubmed: 35672283 DOI: doi:10.1038/s41421-022-00420-3 ]
- Isoform gnas-2 of guanine nucleotide-binding protein g(s) subunit alpha isoforms short (44 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholecystokinin receptor type a (47 kDa, Protein from Homo sapiens)
- Human brain gut peptide cholecystokinin receptors (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Homo sapiens)
- Cholecystokinin receptor1 (Complex from Homo sapiens)
- Nanobody35 (Complex)
- Cck-8 (1 kDa, Protein from Homo sapiens)
- Nanobody 35 (13 kDa, Protein from synthetic construct)
- Gs protein (Complex from Homo sapiens)
- Cck-8 (Complex)
Structural insights into human brain gut peptide cholecystokinin receptors
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7xov
Q-score: -0.079
Ding Y, Zhang H, Liao YY, Chen LN, Ji SY, Qin J, Mao C, Shen DD, Lin L, Wang H, Zhang Y, Li XM
Cell Discov (2022) 8 pp. 55-55 [ Pubmed: 35672283 DOI: doi:10.1038/s41421-022-00420-3 ]
- Isoform gnas-2 of guanine nucleotide-binding protein g(s) subunit alpha isoforms short (44 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholecystokinin receptor1 (Complex)
- Cholecystokinin receptor type a (47 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- 2-[2-[[4-(4-chloranyl-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)-1,3-thiazol-2-yl]carbamoyl]-5,7-dimethyl-indol-1-yl]ethanoic acid (610 Da, Ligand)
- Cholecystokinin receptor1 (Complex from Homo sapiens)
- Nanobody35 (Complex)
- Nanobody 35 (13 kDa, Protein from synthetic construct)
- Gs protein (Complex from Homo sapiens)
Structural insights into human brain gut peptide cholecystokinin receptors
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7xow
Q-score: 0.499
Ding Y, Zhang H, Liao YY, Chen LN, Ji SY, Qin J, Mao C, Shen DD, Lin L, Wang H, Zhang Y, Li XM
Cell Discov (2022) 8 pp. 55-55 [ Pubmed: 35672283 DOI: doi:10.1038/s41421-022-00420-3 ]
- Gastrin (2 kDa, Protein from Homo sapiens)
- Gastrin/cholecystokinin type b receptor (48 kDa, Protein from Homo sapiens)
- Human brain gut peptide cholecystokinin receptors (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
- Gastrin (Complex)
- Scfv16 (28 kDa, Protein from Mus musculus)
- Gs protein (Complex from Homo sapiens)
- Scfc16 (Complex from Mus musculus)
- Cholecystokinin receptor (Complex from Homo sapiens)
catalytic core of human telomerase holoenzyme
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 7v99
Q-score: 0.247
Wan F, Ding Y, Zhang Y, Wu Z, Li S, Yang L, Yan X, Lan P, Li G, Wu J, Lei M
Cell Res (2021) 31 pp. 1275-1290 [ Pubmed: 34782750 DOI: doi:10.1038/s41422-021-00586-7 ]
- Telomerase reverse transcriptase (127 kDa, Protein from Homo sapiens)
- Telomerase rna component (145 kDa, RNA from Homo sapiens)
- Primer dna (7 kDa, DNA from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Catalytic core (Complex from Homo sapiens)
- Histone h2b type 1-k (13 kDa, Protein from Homo sapiens)
masked histone region in the catalytic core of human telomerase holoenzyme
Wan F, Ding Y, Zhang Y, Wu Z, Li S, Yang L, Yan X, Lan P, Li G, Wu J, Lei M
Cell Res (2021) 31 pp. 1275-1290 [ Pubmed: 34782750 DOI: doi:10.1038/s41422-021-00586-7 ]
- Telomerase rna component (RNA from Homo sapiens)
- Histone h2b type 1-k (Protein from Homo sapiens)
- Histone h2a type 1-b/e (Protein from Homo sapiens)
- Telomerase reverse transcriptase (Protein from Homo sapiens)
- Catalytic core (Complex from Homo sapiens)
- Primer dna (DNA from Homo sapiens)
biogenesis module of human telomerase holoenzyme
Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 7v9a
Q-score: 0.254
Wan F, Ding Y, Zhang Y, Wu Z, Li S, Yang L, Yan X, Lan P, Li G, Wu J, Lei M
Cell Res (2021) 31 pp. 1275-1290 [ Pubmed: 34782750 DOI: doi:10.1038/s41422-021-00586-7 ]
- Telomerase rna component (145 kDa, RNA from Homo sapiens)
- H/aca ribonucleoprotein complex subunit 2 (17 kDa, Protein from Homo sapiens)
- Telomerase cajal body protein 1 (59 kDa, Protein from Homo sapiens)
- H/aca ribonucleoprotein complex subunit 1 (22 kDa, Protein from Homo sapiens)
- H/aca ribonucleoprotein complex subunit dkc1 (57 kDa, Protein from Homo sapiens)
- H/aca ribonucleoprotein complex subunit 3 (7 kDa, Protein from Homo sapiens)
- Biogenesis module (Complex from Homo sapiens)