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primary_citation_author:"Doherty E"
HTT in complex with HAP40 in the apo state.
Release date: March 13, 2024
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8w15
Q-score: 0.523
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8w15
Q-score: 0.523
Poweleit N, Boudet J, Doherty E
To Be Published
Sample:
- Htt and hap40 complex (Complex from Homo sapiens)
- 40-kda huntingtin-associated protein (41 kDa, Protein from Homo sapiens)
- Huntingtin (353 kDa, Protein from Homo sapiens)
HTT in complex with HAP40 and a small molecule.
Release date: March 6, 2024
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8vlx
Q-score: 0.544
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8vlx
Q-score: 0.544
Poweleit N, Boudet J, Doherty E
To Be Published
Sample:
- Htt and hap40 complex (Complex from Homo sapiens)
- N-[(1s,2r)-2-benzylcyclopentyl]-n'-{1-[(1s)-1-(pyridin-4-yl)ethyl]piperidin-4-yl}urea (406 Da, Ligand)
- 40-kda huntingtin-associated protein (41 kDa, Protein from Homo sapiens)
- Huntingtin (353 kDa, Protein from Homo sapiens)