Cryo-EM structure of VTC complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7ytj
Q-score: 0.485
Guan Z, Chen J, Liu R, Chen Y, Xing Q, Du Z, Cheng M, Hu J, Zhang W, Mei W, Wan B, Wang Q, Zhang J, Cheng P, Cai H, Cao J, Zhang D, Yan J, Yin P, Hothorn M, Liu Z
Nat Commun (2023) 14 pp. 718-718 [ DOI: doi:10.1038/s41467-023-36466-4 Pubmed: 36759618 ]
- Phosphate ion (94 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Vacuolar transporter chaperone 3 (100 kDa, Protein from Saccharomyces cerevisiae)
- Inositol hexakisphosphate (660 Da, Ligand)
- Vtc complex (Complex from Saccharomyces cerevisiae)
- Vacuolar transporter chaperone 4 (86 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar transporter chaperone 1 (15 kDa, Protein from Saccharomyces cerevisiae)
SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (focused refinement on Fab-RBD)
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 7wh8
Q-score: 0.523
Zhou B, Zhou R, Chan JF, Zeng J, Zhang Q, Yuan S, Liu L, Robinot R, Shan S, Liu N, Ge J, Kwong HY, Zhou D, Xu H, Chan CC, Poon VK, Chu H, Yue M, Kwan KY, Chan CY, Chan CC, Chik KK, Du Z, Au KK, Huang H, Man HO, Cao J, Li C, Wang Z, Zhou J, Song Y, Yeung ML, To KK, Ho DD, Chakrabarti LA, Wang X, Zhang L, Yuen KY, Chen Z
Emerg Microbes Infect (2023) 12 pp. 2245921-2245921 [ Pubmed: 37542391 DOI: doi:10.1080/22221751.2023.2245921 ]
- Spike (Complex)
- Spike glycoprotein (31 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Antibody zb8 light chain (23 kDa, Protein from Homo sapiens)
- Antibody zb8 heavy chain (23 kDa, Protein from Homo sapiens)
- Fab-spike (Complex from Homo sapiens)
- Fab (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (3U)
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 7whb
Q-score: 0.479
Zhou B, Zhou R, Chan JF, Zeng J, Zhang Q, Yuan S, Liu L, Robinot R, Shan S, Liu N, Ge J, Kwong HY, Zhou D, Xu H, Chan CC, Poon VK, Chu H, Yue M, Kwan KY, Chan CY, Chan CC, Chik KK, Du Z, Au KK, Huang H, Man HO, Cao J, Li C, Wang Z, Zhou J, Song Y, Yeung ML, To KK, Ho DD, Chakrabarti LA, Wang X, Zhang L, Yuen KY, Chen Z
Emerg Microbes Infect (2023) 12 pp. 2245921-2245921 [ Pubmed: 37542391 DOI: doi:10.1080/22221751.2023.2245921 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Antibody zb8 light chain (23 kDa, Protein from Homo sapiens)
- Antibody zb8 heavy chain (23 kDa, Protein from Homo sapiens)
- Fab (Complex)
- Spike (Complex from Homo sapiens)
- Spike glycoprotein (124 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab-spike (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (2u1d)
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 7whd
Q-score: 0.128
Zhou B, Zhou R, Chan JF, Zeng J, Zhang Q, Yuan S, Liu L, Robinot R, Shan S, Liu N, Ge J, Kwong HY, Zhou D, Xu H, Chan CC, Poon VK, Chu H, Yue M, Kwan KY, Chan CY, Chan CC, Chik KK, Du Z, Au KK, Huang H, Man HO, Cao J, Li C, Wang Z, Zhou J, Song Y, Yeung ML, To KK, Ho DD, Chakrabarti LA, Wang X, Zhang L, Yuen KY, Chen Z
Emerg Microbes Infect (2023) 12 pp. 2245921-2245921 [ Pubmed: 37542391 DOI: doi:10.1080/22221751.2023.2245921 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Antibody zb8 light chain (23 kDa, Protein from Homo sapiens)
- Antibody zb8 heavy chain (23 kDa, Protein from Homo sapiens)
- Fab (Complex)
- Spike (Complex from Homo sapiens)
- Spike glycoprotein (124 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab-spike (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of human thioredoxin reductase bound by Au
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7x1r
Q-score: 0.448
Du Z, He Z, Fan J, Huo Y, He B, Wang Y, Sun Q, Niu W, Zhao W, Zhao L, Cao P, Cao K, Xia D, Yuan Q, Liang XJ, Jiang H, Gong Y, Gao X
Nano Today (2022) 47 pp. 101686- [ DOI: doi:10.1016/j.nantod.2022.101686 ]
- Thioredoxin reductase 1 (Complex from Homo sapiens)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Thioredoxin reductase 1, cytoplasmic (56 kDa, Protein from Homo sapiens)
- Gold ion (196 Da, Ligand)
BD23-Fab in complex with the S ectodomain trimer
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 7byr
Q-score: 0.441
Cao Y, Su B, Guo X, Sun W, Deng Y, Bao L, Zhu Q, Zhang X, Zheng Y, Geng C, Chai X, He R, Li X, Lv Q, Zhu H, Deng W, Xu Y, Wang Y, Qiao L, Tan Y, Song L, Wang G, Du X, Gao N, Liu J, Xiao J, Su XD, Du Z, Feng Y, Qin C, Qin C, Jin R, Xie XS
Cell (2020) 182 pp. 73-84.e16 [ DOI: doi:10.1016/j.cell.2020.05.025 Pubmed: 32425270 ]
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ab23-fab-heavy chain (13 kDa, Protein from Homo sapiens)
- Ab23-fab-light chain (11 kDa, Protein from Homo sapiens)
- Ab23-fab (Complex from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from SARS coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bd23-fab in complex with the s ectodomain trimer (Complex)