Structure of SARS-CoV-2 (HP-GSAS-Mut7) spike in complex with TXG-0078 Fab -Conformation 1
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Burbach S, Truong A, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B
Cell Rep (2024) 43 pp. 114307-114307 [ Pubmed: 38848216 DOI: doi:10.1016/j.celrep.2024.114307 ]
Structure of SARS-CoV-2 (HP-GSAS-Mut7) spike in complex with TXG-0078 Fab -Conformation 2
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Burbach S, Truong A, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B
Cell Rep (2024) 43 pp. 114307-114307 [ Pubmed: 38848216 DOI: doi:10.1016/j.celrep.2024.114307 ]
Local refinement of SARS-CoV-2 (HP-GSAS-Mut7) spike NTD in complex with TXG-0078 Fab
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 8swh
Q-score: 0.326
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Burbach S, Truong A, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B
Cell Rep (2024) 43 pp. 114307-114307 [ Pubmed: 38848216 DOI: doi:10.1016/j.celrep.2024.114307 ]
- Txg-0078 fab heavy chain (16 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Structure of sars-cov-2(hp-gsas-mut7) spike in complex with txg-0078 fab- local refinement (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Txg-0078 fab light chain (14 kDa, Protein from Homo sapiens)
SARS-2 CoV 6P Mut7 in complex with Fab CC84.5
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schafer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R
Nat Immunol (2022) 23 pp. 960-970 [ Pubmed: 35654851 DOI: doi:10.1038/s41590-022-01222-1 ]
SARS-2 CoV 6P Mut7 in complex with Fab CC25.1
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schafer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R
Nat Immunol (2022) 23 pp. 960-970 [ Pubmed: 35654851 DOI: doi:10.1038/s41590-022-01222-1 ]
SARS-2 CoV 6P Mut7 in complex with Fab CC25.54
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schafer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R
Nat Immunol (2022) 23 pp. 960-970 [ DOI: doi:10.1038/s41590-022-01222-1 Pubmed: 35654851 ]
SARS-2 CoV 6P Mut7 + Fab CC25.52
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schafer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R
Nat Immunol (2022) 23 pp. 960-970 [ Pubmed: 35654851 DOI: doi:10.1038/s41590-022-01222-1 ]
SARS-2 CoV 6P Mut7 in complex with Fab CC25.56
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schafer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R
Nat Immunol (2022) 23 pp. 960-970 [ Pubmed: 35654851 DOI: doi:10.1038/s41590-022-01222-1 ]
SARS-2 CoV 6P Mut7 in complex with Fab CC25.36
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schafer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R
Nat Immunol (2022) 23 pp. 960-970 [ Pubmed: 35654851 DOI: doi:10.1038/s41590-022-01222-1 ]
SARS-2 CoV 6P Mut7 in complex with Fab CC25.3
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schafer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R
Nat Immunol (2022) 23 pp. 960-970 [ Pubmed: 35654851 DOI: doi:10.1038/s41590-022-01222-1 ]