The FBF-2/LST-1/gld-1 RNA complex (one FBF-2)
Qiu C, Crittenden SL, Carrick BH, Dillard LB, Costa Dos Santos SJ, Dandey VP, Dutcher RC, Viverette EG, Wine RN, Woodworth J, Campbell ZT, Wickens M, Borgnia MJ, Kimble J, Hall TMT
Nat Commun (2025) 16 pp. 123-123 [ Pubmed: 39747099 DOI: doi:10.1038/s41467-024-55526-x ]
The FBF-2/LST-1/gld-1 RNA complex (two FBF-2)
Qiu C, Crittenden SL, Carrick BH, Dillard LB, Costa Dos Santos SJ, Dandey VP, Dutcher RC, Viverette EG, Wine RN, Woodworth J, Campbell ZT, Wickens M, Borgnia MJ, Kimble J, Hall TMT
Nat Commun (2025) 16 pp. 123-123 [ Pubmed: 39747099 DOI: doi:10.1038/s41467-024-55526-x ]
- Fbf-2 (Protein from Caenorhabditis elegans)
- Lst-1 (Protein from Caenorhabditis elegans)
- Gld-1 rna (RNA from Caenorhabditis elegans)
- Ternary complex of fbf-2 with lst-1 and rna (Complex from Caenorhabditis elegans)
Riccio AA, Bouvette J, Pedersen LC, Somai S, Dutcher RC, Borgnia MJ, Copeland WC
Nucleic Acids Res (2024) 52 pp. 10329-10340 [ DOI: doi:10.1093/nar/gkae670 Pubmed: 39106165 ]
- Dna2 (DNA from synthetic construct)
- Single-stranded dna-binding protein, mitochondrial (Protein from Homo sapiens)
- Polg, mitochondrial dna polymerase catalytic subunit (Protein from Homo sapiens)
- Dna3 (DNA from synthetic construct)
- Polg2, mitochondrial dna polymerase gamma accessory subunit (Protein from Homo sapiens)
- Dna1 (DNA from synthetic construct)
- The mitchondrial dna polymerase, catalytic (polg) and accessory subunits (polg2), bound to dna in complex with the mitochondrial dna single-stranded binding protein (mtssb) (230 kDa, Complex from Homo sapiens)
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIa
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8dfv
Q-score: 0.447
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall TMT, Zamore PD, Korostelev AA
Mol Cell (2022) 82 pp. 4049-4063.e6 [ Pubmed: 36182693 DOI: doi:10.1016/j.molcel.2022.09.002 ]
- Calcium ion (40 Da, Ligand)
- Loquacious, isoform b (50 kDa, Protein from Drosophila melanogaster)
- Rna (60-mer) (19 kDa, RNA from Drosophila melanogaster)
- Ternary complex of dicer-1 and loqs-pb binding pre-mirna (Complex from Drosophila melanogaster)
- Endoribonuclease dcr-1 (255 kDa, Protein from Drosophila melanogaster)
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIb
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8dg5
Q-score: 0.406
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall TMT, Zamore PD, Korostelev AA
Mol Cell (2022) 82 pp. 4049-4063.e6 [ Pubmed: 36182693 DOI: doi:10.1016/j.molcel.2022.09.002 ]
- Uridine-5'-monophosphate (324 Da, Ligand)
- Loquacious, isoform b (50 kDa, Protein from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
- Ternary complex of dicer-1 and loqs-pb binding pre-mirna (Complex from Drosophila melanogaster)
- Endoribonuclease dcr-1 (255 kDa, Protein from Drosophila melanogaster)
- Rna (60-mer) (18 kDa, RNA from Drosophila melanogaster)
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex III
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8dg7
Q-score: 0.399
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall TMT, Zamore PD, Korostelev AA
Mol Cell (2022) 82 pp. 4049-4063.e6 [ Pubmed: 36182693 DOI: doi:10.1016/j.molcel.2022.09.002 ]
- Rna (22-mer) (6 kDa, RNA from Drosophila melanogaster)
- Rna (38-mer) (11 kDa, RNA from Drosophila melanogaster)
- Uridine-5'-monophosphate (324 Da, Ligand)
- Loquacious, isoform b (50 kDa, Protein from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
- Ternary complex of dicer-1 and loqs-pb binding pre-mirna (Complex from Drosophila melanogaster)
- Endoribonuclease dcr-1 (255 kDa, Protein from Drosophila melanogaster)
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IV
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 8dga
Q-score: 0.267
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall TMT, Zamore PD, Korostelev AA
Mol Cell (2022) 82 pp. 4049-4063.e6 [ Pubmed: 36182693 DOI: doi:10.1016/j.molcel.2022.09.002 ]
- Rna (22-mer) (6 kDa, RNA from Drosophila melanogaster)
- Uridine-5'-monophosphate (324 Da, Ligand)
- Loquacious, isoform b (50 kDa, Protein from Drosophila melanogaster)
- Ternary complex of dicer-1 and loqs-pb binding mirna (Complex from Drosophila melanogaster)
- Rna (22-mer) (6 kDa, RNA from Drosophila melanogaster)
- Endoribonuclease dcr-1 (255 kDa, Protein from Drosophila melanogaster)
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ia
Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 8dgi
Q-score: 0.206
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall TMT, Zamore PD, Korostelev AA
Mol Cell (2022) 82 pp. 4049-4063.e6 [ Pubmed: 36182693 DOI: doi:10.1016/j.molcel.2022.09.002 ]
- Endoribonuclease dcr-1 (255 kDa, Protein from Drosophila melanogaster)
- Loquacious, isoform b (50 kDa, Protein from Drosophila melanogaster)
- Complex of dicer-1 and loqs-pb (Complex from Drosophila melanogaster)
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ib
Resolution: 4.02 Å
EM Method: Single-particle
Fitted PDBs: 8dgj
Q-score: 0.251
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall TMT, Zamore PD, Korostelev AA
Mol Cell (2022) 82 pp. 4049-4063.e6 [ Pubmed: 36182693 DOI: doi:10.1016/j.molcel.2022.09.002 ]
- Endoribonuclease dcr-1 (255 kDa, Protein from Drosophila melanogaster)
- Loquacious, isoform b (50 kDa, Protein from Drosophila melanogaster)
- Complex of dicer-1 and loqs-pb (Complex from Drosophila melanogaster)