Structure of two molecules of the chromatin remodelling enzyme Chd1 bound to a nucleosome
Resolution: 10.0 Å
EM Method: Single-particle
Fitted PDBs: 6g0l
Q-score: 0.095
Sundaramoorthy R, Hughes AL, El-Mkami H, Norman DG, Ferreira H, Owen-Hughes T
eLife (2018) 7 [ DOI: doi:10.7554/eLife.35720 Pubmed: 30079888 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- X. laevis nucleosome pn 601 dna with s.cerevisiae remodeller chd1 (Complex from synthetic construct)
- Histone h2a type 1 (14 kDa, Protein from Xenopus laevis)
- Histone h2a type 1 (14 kDa, Protein from Xenopus laevis)
- Dna (177-mer) (54 kDa, DNA from synthetic construct)
- Chromo domain-containing protein 1 (168 kDa, Protein from Saccharomyces cerevisiae S288C)
- X. laevis nucleosome pn 601 dna with s.cerevisiae remodeller chd1 (Complex from Saccharomyces cerevisiae S288C)
- Beryllium trifluoride ion (66 Da, Ligand)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- X. laevis nucleosome pn 601 dna with s.cerevisiae remodeller chd1 (600 kDa, Complex)
- Histone h4 (13 kDa, Protein from Xenopus laevis)
- X. laevis nucleosome pn 601 dna with s.cerevisiae remodeller chd1 (Complex from Xenopus laevis)
- Dna (176-mer) (54 kDa, DNA from synthetic construct)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6ftx
Q-score: 0.23
Sundaramoorthy R, Hughes AL, El-Mkami H, Norman DG, Ferreira H, Owen-Hughes T
eLife (2018) 7 [ DOI: doi:10.7554/eLife.35720 Pubmed: 30079888 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Histone h2b (13 kDa, Protein from Xenopus tropicalis)
- X. laevis nucleosome pn 601 dna with s.cerevisiae remodeller chd1 (Complex from synthetic construct)
- X. laevis nucleosome pn 601 dna with s.cerevisiae remodeller chd1 (Complex from Homo sapiens)
- Histone h2a type 1 (14 kDa, Protein from Xenopus laevis)
- Histone h3 (11 kDa, Protein from Petromyzon marinus)
- X. laevis nucleosome pn 601 dna with s.cerevisiae remodeller chd1 (Complex from Saccharomyces cerevisiae)
- X. laevis nucleosome pn 601 dna with s.cerevisiae remodeller chd1 (450 kDa, Complex)
- Dna (160-mer) (49 kDa, DNA from synthetic construct)
- Polyubiquitin-b (8 kDa, Protein from Homo sapiens)
- Chromatin-remodeling atpase (102 kDa, Protein from Saccharomyces cerevisiae)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Beryllium trifluoride ion (66 Da, Ligand)
- X. laevis nucleosome pn 601 dna with s.cerevisiae remodeller chd1 (Complex from Xenopus laevis)
- Histone h3.3c (12 kDa, Protein from Xenopus laevis)
- Dna (159-mer) (48 kDa, DNA from synthetic construct)
Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes
Sundaramoorthy R, Hughes AL, Singh V, Wiechens N, Ryan DP, El-Mkami H, Petoukhov M, Svergun DI, Treutlein B, Quack S, Fischer M, Michaelis J, Bottcher B, Norman DG, Owen-Hughes T
eLife (2017) 6 [ Pubmed: 28332978 DOI: doi:10.7554/eLife.22510 ]
- Chd1-nucleosome complex (400 kDa, Complex)
- Nucleosome (Complex from Xenopus laevis)
- Chromodomain-helicase-dna containing protein (Macromolecule)
- Chd1 (Complex from Saccharomyces cerevisiae)
Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes.
Sundaramoorthy R, Hughes AL, Singh V, Wiechens N, Ryan DP, El-Mkami H, Petoukhov M, Svergun DI, Treutlein B, Quack S, Fischer M, Michaelis J, Bottcher B, Norman DG, Owen-Hughes T
eLife (2017) 6 [ Pubmed: 28332978 DOI: doi:10.7554/eLife.22510 ]
- Chd1 (Complex from Saccharomyces cerevisiae)
- Chd1-nucleosome complex (400 kDa, Complex)
- Chromodomain helicase dna binding protein (Macromolecule)
- Nucleosome (Complex from Xenopus laevis)