SARS-CoV-2 S trimer with one RBD in the open state and complexed with one H014 Fab.
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 7cac
Q-score: 0.327
Lv Z, Deng YQ, Ye Q, Cao L, Sun CY, Fan C, Huang W, Sun S, Sun Y, Zhu L, Chen Q, Wang N, Nie J, Cui Z, Zhu D, Shaw N, Li XF, Li Q, Xie L, Wang Y, Rao Z, Qin CF, Wang X
Science (2020) 369 pp. 1505-1509 [ Pubmed: 32703908 DOI: doi:10.1126/science.abc5881 ]
- Light chain of h014 fab (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein complex with h014 fab (680 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- H014 fab (Complex)
- Heavy chain of h014 fab (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 7cab
Q-score: 0.476
SARS-CoV-2 S trimer with two RBDs in the open state and complexed with two H014 Fab
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 7cai
Q-score: 0.331
Lv Z, Deng YQ, Ye Q, Cao L, Sun CY, Fan C, Huang W, Sun S, Sun Y, Zhu L, Chen Q, Wang N, Nie J, Cui Z, Zhu D, Shaw N, Li XF, Li Q, Xie L, Wang Y, Rao Z, Qin CF, Wang X
Science (2020) 369 pp. 1505-1509 [ Pubmed: 32703908 DOI: doi:10.1126/science.abc5881 ]
- Sars-cov-2 s trimer with tow rbd in the open state and complexed with one h014 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of h014 fab (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- H014 fab (Complex)
- Heavy chain of h014 fab (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 s (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 S trimer with three RBD in the open state and complexed with three H014 Fab
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7cak
Q-score: 0.362
Lv Z, Deng YQ, Ye Q, Cao L, Sun CY, Fan C, Huang W, Sun S, Sun Y, Zhu L, Chen Q, Wang N, Nie J, Cui Z, Zhu D, Shaw N, Li XF, Li Q, Xie L, Wang Y, Rao Z, Qin CF, Wang X
Science (2020) 369 pp. 1505-1509 [ Pubmed: 32703908 DOI: doi:10.1126/science.abc5881 ]
- Light chain of h014 fab (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 s trimer with three rbd in the open state and complexed with three h014 fab (Complex)
- Sars-cov-2 s (Complex from Severe acute respiratory syndrome coronavirus 2)
- H014 fab (Complex from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of h014 fab (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
The interface of H014 Fab binds to SARS-CoV-2 S
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7cah
Q-score: 0.387
Lv Z, Deng YQ, Ye Q, Cao L, Sun CY, Fan C, Huang W, Sun S, Sun Y, Zhu L, Chen Q, Wang N, Nie J, Cui Z, Zhu D, Shaw N, Li XF, Li Q, Xie L, Wang Y, Rao Z, Qin CF, Wang X
Science (2020) 369 pp. 1505-1509 [ Pubmed: 32703908 DOI: doi:10.1126/science.abc5881 ]
- The interface of h014 fab binds to sars-cov-2 s (Complex from Homo sapiens)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s (Complex)
- Heavy chain of h014 fab (23 kDa, Protein from Homo sapiens)
- Light chain of h014 fab (11 kDa, Protein from Homo sapiens)
- H014 fab (Complex from Severe acute respiratory syndrome coronavirus 2)