Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8v7z
Q-score: 0.496
Gao X, Yeh HI, Yang Z, Fan C, Jiang F, Howard RJ, Lindahl E, Kappes JC, Hwang TC
Nat Commun (2024) 15 pp. 6668-6668 [ Pubmed: 39107303 DOI: doi:10.1038/s41467-024-50641-1 ]
- E1371q-cftr (Complex from Homo sapiens)
- Cystic fibrosis transmembrane conductance regulator (161 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8v81
Q-score: 0.507
Gao X, Yeh HI, Yang Z, Fan C, Jiang F, Howard RJ, Lindahl E, Kappes JC, Hwang TC
Nat Commun (2024) 15 pp. 6668-6668 [ Pubmed: 39107303 DOI: doi:10.1038/s41467-024-50641-1 ]
- E1371q-cftr (Complex from Homo sapiens)
- 4-[(z)-{(3m)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl]benzoic acid (409 Da, Ligand)
- Cystic fibrosis transmembrane conductance regulator (163 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
Cryo-EM structure of the Arabidopsis thaliana photosystem I(PSI-LHCII-ST2)
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8j6z
Q-score: 0.587
Wu J, Chen S, Wang C, Lin W, Huang C, Fan C, Han D, Lu D, Xu X, Sui S, Zhang L
Mol Plant (2023) 16 pp. 1937-1950 [ DOI: doi:10.1016/j.molp.2023.11.002 Pubmed: 37936349 ]
- Photosystem i p700 chlorophyll a apoprotein a2 (82 kDa, Protein from Arabidopsis thaliana)
- Phylloquinone (450 Da, Ligand)
- Photosystem i reaction center subunit v, chloroplastic (17 kDa, Protein from Arabidopsis thaliana)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Photosystem i subunit o (15 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit xi, chloroplastic (23 kDa, Protein from Arabidopsis thaliana)
- Beta-carotene (536 Da, Ligand)
- Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll a-b binding protein 6, chloroplastic (26 kDa, Protein from Arabidopsis thaliana)
- (1r,3r)-6-{(3e,5e,7e,9e,11e,13e,15e,17e)-18-[(1s,4r,6r)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenylidene}-1,5,5-trimethylcyclohexane-1,3-diol (600 Da, Ligand)
- Chlorophyll b (907 Da, Ligand)
- Photosystem i reaction center subunit ix (5 kDa, Protein from Arabidopsis thaliana)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Chlorophyll a-b binding protein 4, chloroplastic (27 kDa, Protein from Arabidopsis thaliana)
- Photosystem i iron-sulfur center (9 kDa, Protein from Arabidopsis thaliana)
- Photosystem i (Complex from Arabidopsis thaliana)
- Chlorophyll a-b binding protein 2, chloroplastic (28 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll a-b binding protein 2.1, chloroplastic (28 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll a (893 Da, Ligand)
- (3s,5r,6s,3's,5'r,6's)-5,6,5',6'-diepoxy-5,6,5',6'- tetrahydro-beta,beta-carotene-3,3'-diol (600 Da, Ligand)
- Chlorophyll a isomer (893 Da, Ligand)
- Photosystem i reaction center subunit psak, chloroplastic (13 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit vi-2, chloroplastic (15 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iii, chloroplastic (24 kDa, Protein from Arabidopsis thaliana)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- (3r,3'r,6s)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol (568 Da, Ligand)
- Photosystem i chlorophyll a/b-binding protein 3-1, chloroplastic (29 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit viii (4 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iv a, chloroplastic (14 kDa, Protein from Arabidopsis thaliana)
- Iron/sulfur cluster (351 Da, Ligand)
- Photosystem i chlorophyll a/b-binding protein 2, chloroplastic (27 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit ii-2, chloroplastic (22 kDa, Protein from Arabidopsis thaliana)
Coordinates of Cryo-EM structure of the Arabidopsis thaliana PSI in state 1 (PSI-ST1)
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8j7a
Q-score: 0.549
Wu J, Chen S, Wang C, Lin W, Huang C, Fan C, Han D, Lu D, Xu X, Sui S, Zhang L
Mol Plant (2023) 16 pp. 1937-1950 [ DOI: doi:10.1016/j.molp.2023.11.002 Pubmed: 37936349 ]
- Photosystem i p700 chlorophyll a apoprotein a2 (82 kDa, Protein from Arabidopsis thaliana)
- Phylloquinone (450 Da, Ligand)
- Photosystem i reaction center subunit v, chloroplastic (17 kDa, Protein from Arabidopsis thaliana)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Photosystem i reaction center subunit xi, chloroplastic (23 kDa, Protein from Arabidopsis thaliana)
- Beta-carotene (536 Da, Ligand)
- Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll a-b binding protein 6, chloroplastic (26 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll b (907 Da, Ligand)
- Photosystem i reaction center subunit ix (5 kDa, Protein from Arabidopsis thaliana)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Chlorophyll a-b binding protein 4, chloroplastic (27 kDa, Protein from Arabidopsis thaliana)
- Photosystem i iron-sulfur center (9 kDa, Protein from Arabidopsis thaliana)
- Cryo-em structure of the arabidopsis thaliana photosystem i(psi-lhcii-st2) (Complex from Arabidopsis thaliana)
- Chlorophyll a (893 Da, Ligand)
- (3s,5r,6s,3's,5'r,6's)-5,6,5',6'-diepoxy-5,6,5',6'- tetrahydro-beta,beta-carotene-3,3'-diol (600 Da, Ligand)
- Chlorophyll a isomer (893 Da, Ligand)
- Photosystem i reaction center subunit psak, chloroplastic (13 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit vi-2, chloroplastic (15 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iii, chloroplastic (24 kDa, Protein from Arabidopsis thaliana)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- (3r,3'r,6s)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol (568 Da, Ligand)
- Photosystem i chlorophyll a/b-binding protein 3-1, chloroplastic (29 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit viii (4 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iv a, chloroplastic (14 kDa, Protein from Arabidopsis thaliana)
- Iron/sulfur cluster (351 Da, Ligand)
- Photosystem i chlorophyll a/b-binding protein 2, chloroplastic (27 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit ii-2, chloroplastic (22 kDa, Protein from Arabidopsis thaliana)
Coordinates of Cryo-EM structure of the Arabidopsis thaliana PSI in state 2 (PSI-ST2)
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 8j7b
Q-score: 0.576
Wu J, Chen S, Wang C, Lin W, Huang C, Fan C, Han D, Lu D, Xu X, Sui S, Zhang L
Mol Plant (2023) 16 pp. 1937-1950 [ DOI: doi:10.1016/j.molp.2023.11.002 Pubmed: 37936349 ]
- Photosystem i p700 chlorophyll a apoprotein a2 (82 kDa, Protein from Arabidopsis thaliana)
- Phylloquinone (450 Da, Ligand)
- Photosystem i reaction center subunit v, chloroplastic (17 kDa, Protein from Arabidopsis thaliana)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Photosystem i reaction center subunit xi, chloroplastic (23 kDa, Protein from Arabidopsis thaliana)
- Beta-carotene (536 Da, Ligand)
- Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll a-b binding protein 6, chloroplastic (26 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll b (907 Da, Ligand)
- Photosystem i reaction center subunit ix (5 kDa, Protein from Arabidopsis thaliana)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Chlorophyll a-b binding protein 4, chloroplastic (27 kDa, Protein from Arabidopsis thaliana)
- Photosystem i iron-sulfur center (9 kDa, Protein from Arabidopsis thaliana)
- Cryo-em structure of the arabidopsis thaliana photosystem i(psi-lhcii-st2) (Complex from Arabidopsis thaliana)
- Chlorophyll a (893 Da, Ligand)
- (3s,5r,6s,3's,5'r,6's)-5,6,5',6'-diepoxy-5,6,5',6'- tetrahydro-beta,beta-carotene-3,3'-diol (600 Da, Ligand)
- Chlorophyll a isomer (893 Da, Ligand)
- Photosystem i reaction center subunit psak, chloroplastic (13 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit vi-2, chloroplastic (15 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iii, chloroplastic (24 kDa, Protein from Arabidopsis thaliana)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- (3r,3'r,6s)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol (568 Da, Ligand)
- Photosystem i chlorophyll a/b-binding protein 3-1, chloroplastic (29 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit viii (4 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iv a, chloroplastic (14 kDa, Protein from Arabidopsis thaliana)
- Iron/sulfur cluster (351 Da, Ligand)
- Photosystem i chlorophyll a/b-binding protein 2, chloroplastic (27 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit ii-2, chloroplastic (22 kDa, Protein from Arabidopsis thaliana)
Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8fyi
Q-score: 0.493
Dam KA, Fan C, Yang Z, Bjorkman PJ
Nature (2023) 623 pp. 1017-1025 [ Pubmed: 37993719 DOI: doi:10.1038/s41586-023-06639-8 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (14 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 env trimer bg505 sosip.664 in complex with one cd4 molecule (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
- T-cell surface glycoprotein cd4 (42 kDa, Protein from Homo sapiens)
Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8fyj
Q-score: 0.357
Dam KA, Fan C, Yang Z, Bjorkman PJ
Nature (2023) 623 pp. 1017-1025 [ Pubmed: 37993719 DOI: doi:10.1038/s41586-023-06639-8 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 env trimer bg505 sosip.664 in complex with two cd4 molecules (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
- T-cell surface glycoprotein cd4 (42 kDa, Protein from Homo sapiens)
CryoEM structure of human rho1 GABAA receptor in complex with GABA
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 8op9
Q-score: 0.484
Cowgill J, Fan C, Haloi N, Tobiasson V, Zhuang Y, Howard RJ, Lindahl E
Neuron (2023) 111 pp. 3450-3464.e5 [ DOI: doi:10.1016/j.neuron.2023.08.006 Pubmed: 37659407 ]
- Hexane (86 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rho1 gabaa receptor (Complex from Homo sapiens)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit rho-1 (55 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Chloride ion (35 Da, Ligand)
CryoEM structure of human rho1 GABAA receptor apo state
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8oq6
Q-score: 0.559
Cowgill J, Fan C, Haloi N, Tobiasson V, Zhuang Y, Howard RJ, Lindahl E
Neuron (2023) 111 pp. 3450- [ DOI: doi:10.1016/j.neuron.2023.08.006 Pubmed: 37659407 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit rho-1 (55 kDa, Protein from Homo sapiens)
- Human rho1 gabaa receptor (Complex from Homo sapiens)
- [(2r)-2-heptanoyloxy-3-phosphonooxy-propyl] nonanoate (424 Da, Ligand)
- Decane (142 Da, Ligand)
- N-octane (114 Da, Ligand)
- Water (18 Da, Ligand)
- Chloride ion (35 Da, Ligand)
CryoEM structure of human rho1 GABAA receptor in complex with inhibitor TPMPA
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8oq7
Q-score: 0.712
Cowgill J, Fan C, Haloi N, Tobiasson V, Zhuang Y, Howard RJ, Lindahl E
Neuron (2023) 111 pp. 3450- [ DOI: doi:10.1016/j.neuron.2023.08.006 Pubmed: 37659407 ]
- Methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid (161 Da, Ligand)
- Hexane (86 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Water (18 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit rho-1 (55 kDa, Protein from Homo sapiens)
- Human rho1 gabaa receptor (Complex from Homo sapiens)
- Decane (142 Da, Ligand)
- N-octane (114 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Dodecane (170 Da, Ligand)