Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Enterovirus a71 mature virion in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Fab h1a6.2 (Complex from Mus)
Cryo-EM structure of enterovirus A71 A-particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Enterovirus 71 a-particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Fab h1a6.2 (Complex from Mus)
Cryo-EM structure of enterovirus A71 empty particle
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of enterovirus A71 mature virion
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM Structure of FGF23-FGFR4-aKlotho-HS Quaternary Complex
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 7ysw
Q-score: 0.482
Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M
Nature (2023) 618 pp. 862-870 [ Pubmed: 37286607 DOI: doi:10.1038/s41586-023-06155-9 ]
- Klotho (108 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Fibroblast growth factor 23 (20 kDa, Protein from Homo sapiens)
- 1:2:1:1 fgf23-fgfr4-aklotho-hs quaternary complex (Complex from Homo sapiens)
- Copper (ii) ion (63 Da, Ligand)
- Fgfr4-aklotho-hs (Complex)
- Fibroblast growth factor receptor 4 (23 kDa, Protein from Homo sapiens)
- Fgf23 (Complex)
Cryo-EM Structure of FGF23-FGFR1c-aKlotho-HS Quaternary Complex
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 7ysh
Q-score: 0.555
Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M
Nature (2023) 618 pp. 862-870 [ Pubmed: 37286607 DOI: doi:10.1038/s41586-023-06155-9 ]
- Isoform 20 of fibroblast growth factor receptor 1 (26 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Klotho (109 kDa, Protein from Homo sapiens)
- 1:2:1:1 fgf23-fgfr1c-aklotho-hs quaternary complex (Complex from Homo sapiens)
- Fibroblast growth factor 23 (30 kDa, Protein from Homo sapiens)
- Copper (ii) ion (63 Da, Ligand)
Cryo-EM Structure of FGF23-FGFR3c-aKlotho-HS Quaternary Complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ysu
Q-score: 0.479
Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M
Nature (2023) 618 pp. 862-870 [ Pubmed: 37286607 DOI: doi:10.1038/s41586-023-06155-9 ]
- Fibroblast growth factor receptor 3 (23 kDa, Protein from Homo sapiens)
- Klotho (108 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 1:2:1:1 fgf23-fgfr3c-aklotho-hs quaternary complex (Complex)
- Fibroblast growth factor 23 (20 kDa, Protein from Homo sapiens)
- Fgf23 (Complex from Homo sapiens)
- Copper (ii) ion (63 Da, Ligand)
- Aklotho,fgfr3 (Complex from Homo sapiens)
S protein of SARS-CoV-2 in complex bound with P36-5D2(state2)
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 7fae
Q-score: 0.292
Shan S, Mok CK, Zhang S, Lan J, Li J, Yang Z, Wang R, Cheng L, Fang M, Aw ZQ, Yu J, Zhang Q, Shi X, Zhang T, Zhang Z, Wang J, Wang X, Chu JJH, Zhang L
Front Immunol (2021) 12 pp. 766821-766821 [ DOI: doi:10.3389/fimmu.2021.766821 Pubmed: 34966387 ]
- S protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- P36-5d2 light chain (25 kDa, Protein from Homo sapiens)
- P36-5d2 antibody fab (Complex)
- P36-5d2 heavy chain (51 kDa, Protein from Homo sapiens)
- S protein of sars-cov-2 in complex bound with p36-5d2 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)