Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement)
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ DOI: doi:10.1038/s41564-024-01822-7 Pubmed: 39424982 ]
- The fab of h1a6.2 (Complex from Mus musculus)
- Genome polyprotein (26 kDa, Protein from Coxsackievirus A16)
- Genome polyprotein (27 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- The heavy chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- The light chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
Cryo-EM Structure of FGF23-FGFR4-aKlotho-HS Quaternary Complex
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 7ysw
Q-score: 0.482
Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M
Nature (2023) 618 pp. 862-870 [ Pubmed: 37286607 DOI: doi:10.1038/s41586-023-06155-9 ]
- Klotho (108 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Fibroblast growth factor 23 (20 kDa, Protein from Homo sapiens)
- 1:2:1:1 fgf23-fgfr4-aklotho-hs quaternary complex (Complex from Homo sapiens)
- Copper (ii) ion (63 Da, Ligand)
- Fgfr4-aklotho-hs (Complex)
- Fibroblast growth factor receptor 4 (23 kDa, Protein from Homo sapiens)
- Fgf23 (Complex)
Cryo-EM Structure of FGF23-FGFR1c-aKlotho-HS Quaternary Complex
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 7ysh
Q-score: 0.555
Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M
Nature (2023) 618 pp. 862-870 [ Pubmed: 37286607 DOI: doi:10.1038/s41586-023-06155-9 ]
- Isoform 20 of fibroblast growth factor receptor 1 (26 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Klotho (109 kDa, Protein from Homo sapiens)
- 1:2:1:1 fgf23-fgfr1c-aklotho-hs quaternary complex (Complex from Homo sapiens)
- Fibroblast growth factor 23 (30 kDa, Protein from Homo sapiens)
- Copper (ii) ion (63 Da, Ligand)
Cryo-EM Structure of FGF23-FGFR3c-aKlotho-HS Quaternary Complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ysu
Q-score: 0.479
Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M
Nature (2023) 618 pp. 862-870 [ Pubmed: 37286607 DOI: doi:10.1038/s41586-023-06155-9 ]
- Fibroblast growth factor receptor 3 (23 kDa, Protein from Homo sapiens)
- Klotho (108 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 1:2:1:1 fgf23-fgfr3c-aklotho-hs quaternary complex (Complex)
- Fibroblast growth factor 23 (20 kDa, Protein from Homo sapiens)
- Fgf23 (Complex from Homo sapiens)
- Copper (ii) ion (63 Da, Ligand)
- Aklotho,fgfr3 (Complex from Homo sapiens)
Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7dpz
Q-score: 0.511
Xu L, Zheng Q, Zhu R, Yin Z, Yu H, Lin Y, Wu Y, He M, Huang Y, Jiang Y, Sun H, Zha Z, Yang H, Huang Q, Zhang D, Chen Z, Ye X, Han J, Yang L, Liu C, Que Y, Fang M, Gu Y, Zhang J, Luo W, Zhou ZH, Li S, Cheng T, Xia N
Cell Host Microbe (2021) 29 pp. 448-462.e5 [ DOI: doi:10.1016/j.chom.2021.01.001 Pubmed: 33539764 ]
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus and adenovirus receptor (13 kDa, Protein from Homo sapiens)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR at physiological temperature
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7dq1
Q-score: 0.512
Xu L, Zheng Q, Zhu R, Yin Z, Yu H, Lin Y, Wu Y, He M, Huang Y, Jiang Y, Sun H, Zha Z, Yang H, Huang Q, Zhang D, Chen Z, Ye X, Han J, Yang L, Liu C, Que Y, Fang M, Gu Y, Zhang J, Luo W, Zhou ZH, Li S, Cheng T, Xia N
Cell Host Microbe (2021) 29 pp. 448-462.e5 [ DOI: doi:10.1016/j.chom.2021.01.001 Pubmed: 33539764 ]
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus and adenovirus receptor (13 kDa, Protein from Homo sapiens)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)