Resolution: 2.11 Å
EM Method: Single-particle
Fitted PDBs: 8z8z
Q-score: 0.589
Xiong Q, Zhu Z, Li T, Li X, Zhou Z, Chao Y, Yang C, Feng S, Qu Q, Li D
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01474-5 Pubmed: 39824977 ]
- Water (18 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (4~{z},7~{z},10~{z},13~{z},16~{z},19~{z})-docosa-4,7,10,13,16,19-hexaenoate (764 Da, Ligand)
- Lychos (127 kDa, Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Lysosomal cholesterol signaling protein,fluorescent protein (127 kDa, Protein from synthetic construct)
Scalable protein design using hallucination in a relaxed sequence space
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 9f0l
Q-score: 0.52
Frank C, Khoshouei A, Fu beta L, Schiwietz D, Putz D, Weber L, Zhao Z, Hattori M, Feng S, de Stigter Y, Ovchinnikov S, Dietz H
Science (2024) 386 pp. 439-445 [ DOI: doi:10.1126/science.adq1741 Pubmed: 39446959 ]
- De novo designed protein k10 (106 kDa, Protein from synthetic construct)
- De novo designed protein k10 (106 kDa, Cellular component from synthetic construct)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8xqw
Q-score: 0.502
Liang K, Zhan X, Li Y, Yang Y, Xie Y, Jin Z, Xu X, Zhang W, Lu Y, Zhang S, Zou Y, Feng S, Wu J, Yan Z
Cell (2024) 187 pp. 5638-5650.e18 [ DOI: doi:10.1016/j.cell.2024.08.002 Pubmed: 39197449 ]
- Ctap7 (71 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap1 (107 kDa, Protein from Chlamydomonas reinhardtii)
- Fhl3 (120 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam29 (29 kDa, Protein from Chlamydomonas reinhardtii)
- 1,2-di-o-acyl-3-o-[6-deoxy-6-sulfo-alpha-d-glucopyranosyl]-sn-glycerol (795 Da, Ligand)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Pcya (61 kDa, Protein from Chlamydomonas reinhardtii)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Beta-sitosterol (416 Da, Ligand)
- Ycf2 (342 kDa, Protein from Chlamydomonas reinhardtii)
- Fhl1 (128 kDa, Protein from Chlamydomonas reinhardtii)
- Unk (7 kDa, Protein from Chlamydomonas reinhardtii)
- Dnaj (50 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap6 (109 kDa, Protein from Chlamydomonas reinhardtii)
- Tic22 (40 kDa, Protein from Chlamydomonas reinhardtii)
- The ycf2-ftshi motor complex from chlamydomonas (Complex from Chlamydomonas reinhardtii)
- Acp (12 kDa, Protein from Chlamydomonas reinhardtii)
- Fadl (70 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam31 (31 kDa, Protein from Chlamydomonas reinhardtii)
- Diacyl glycerol (625 Da, Ligand)
- Arhl (51 kDa, Protein from Chlamydomonas reinhardtii)
- Unk (13 kDa, Protein from Chlamydomonas reinhardtii)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Crtam15 (15 kDa, Protein from Chlamydomonas reinhardtii)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Crtam39 (39 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam34 (34 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam49 (48 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam35 (34 kDa, Protein from Chlamydomonas reinhardtii)
Cryo-EM structure of the Ycf2-FtsHi motor complex from chlamydomonas reinhardtii in apo state
Liang K, Zhan X, Li Y, Yang Y, Xie Y, Jin Z, Xu X, Zhang W, Lu Y, Zhang S, Zou Y, Feng S, Wu J, Yan Z
Cell (2024) 187 pp. 5638-5650.e18 [ DOI: doi:10.1016/j.cell.2024.08.002 Pubmed: 39197449 ]
- Ctap7 (71 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap1 (107 kDa, Protein from Chlamydomonas reinhardtii)
- Fhl3 (120 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam29 (29 kDa, Protein from Chlamydomonas reinhardtii)
- 1,2-di-o-acyl-3-o-[6-deoxy-6-sulfo-alpha-d-glucopyranosyl]-sn-glycerol (795 Da, Ligand)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Pcya (61 kDa, Protein from Chlamydomonas reinhardtii)
- Beta-sitosterol (416 Da, Ligand)
- Ycf2 (342 kDa, Protein from Chlamydomonas reinhardtii)
- Fhl1 (128 kDa, Protein from Chlamydomonas reinhardtii)
- Unk (7 kDa, Protein from Chlamydomonas reinhardtii)
- Dnaj (50 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap6 (109 kDa, Protein from Chlamydomonas reinhardtii)
- Tic22 (40 kDa, Protein from Chlamydomonas reinhardtii)
- The ycf2-ftshi motor complex from chlamydomonas (Complex from Chlamydomonas reinhardtii)
- Acp (12 kDa, Protein from Chlamydomonas reinhardtii)
- Fadl (70 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam31 (31 kDa, Protein from Chlamydomonas reinhardtii)
- Diacyl glycerol (625 Da, Ligand)
- Arhl (51 kDa, Protein from Chlamydomonas reinhardtii)
- Unk (13 kDa, Protein from Chlamydomonas reinhardtii)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Crtam15 (15 kDa, Protein from Chlamydomonas reinhardtii)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Crtam39 (39 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam34 (34 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam49 (48 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam35 (34 kDa, Protein from Chlamydomonas reinhardtii)
Cryo-EM structure of the mouse TRPM8 channel in complex with the antagonist TC-I 2014
Yin Y, Park CG, Zhang F, G Fedor J, Feng S, Suo Y, Im W, Lee SY
Sci Adv (2024) 10 pp. eadp2211-eadp2211 [ DOI: doi:10.1126/sciadv.adp2211 Pubmed: 39093967 ]
- Transient receptor potential cation channel subfamily m member 8 (Complex from Mus musculus)
- Cholesterol hemisuccinate (486 Da, Ligand)
- 3-{7-(trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1h-benzimidazol-2-yl}-1-oxa-2-azaspiro[4.5]dec-2-ene (467 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 8 (131 kDa, Protein from Mus musculus)
Cryo-EM structure of the mouse TRPM8 channel in complex with the antagonist AMTB
Yin Y, Park CG, Zhang F, G Fedor J, Feng S, Suo Y, Im W, Lee SY
Sci Adv (2024) 10 pp. eadp2211-eadp2211 [ DOI: doi:10.1126/sciadv.adp2211 Pubmed: 39093967 ]
- Transient receptor potential cation channel subfamily m member 8 (Complex from Mus musculus)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 8 (131 kDa, Protein from Mus musculus)
- N-(3-aminopropyl)-2-[(3-methylphenyl)methoxy]-n-[(thiophen-2-yl)methyl]benzamide (394 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Yin Y, Park CG, Zhang F, G Fedor J, Feng S, Suo Y, Im W, Lee SY
Sci Adv (2024) 10 pp. eadp2211-eadp2211 [ DOI: doi:10.1126/sciadv.adp2211 Pubmed: 39093967 ]
- Transient receptor potential cation channel subfamily m member 8 (Complex from Mus musculus)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 8 (131 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 3-{7-(trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1h-benzimidazol-2-yl}-1-oxa-2-azaspiro[4.5]dec-2-ene (467 Da, Ligand)
- Nonyl(oxo)di(propan-2-yl)-lambda~5~-phosphane (260 Da, Ligand)
Cryo-EM structure of tomato NRC2 dimer
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8xuo
Q-score: 0.419
Ma S, An C, Lawson AW, Cao Y, Sun Y, Tan EYJ, Pan J, Jirschitzka J, Kummel F, Mukhi N, Han Z, Feng S, Wu B, Schulze-Lefert P, Chai J
Nature (2024) 632 pp. 869-876 [ DOI: doi:10.1038/s41586-024-07668-7 Pubmed: 38866053 ]
- Inositol hexakisphosphate (660 Da, Ligand)
- Nrc2 (86 kDa, Protein from Solanum lycopersicum)
- Nrc2 dimer (Complex from Solanum lycopersicum)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM structure of the TUG891 bound GPR120-Giq complex(mask on receptor)
Mao C, Xiao P, Tao XN, Qin J, He QT, Zhang C, Guo SC, Du YQ, Chen LN, Shen DD, Yang ZS, Zhang HQ, Huang SM, He YH, Cheng J, Zhong YN, Shang P, Chen J, Zhang DL, Wang QL, Liu MX, Li GY, Guo Y, Xu HE, Wang C, Zhang C, Feng S, Yu X, Zhang Y, Sun JP
Science (2023) 380 pp. eadd6220-eadd6220 [ Pubmed: 36862765 DOI: doi:10.1126/science.add6220 ]