Cryo-EM structure of uropathogenic Escherichia coli CysK:CdiA:tRNA complex A
To Be Published
- Trnailegau (25 kDa, RNA from Escherichia coli)
- Cysteine synthase a (34 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- Cysk in complex with cdia-ct and trna. (110 kDa, Complex from Escherichia coli 536)
- Trna nuclease cdia (25 kDa, Protein from Escherichia coli 536)
Cryo-EM structure of uropathogenic Escherichia coli CysK:CdiA:tRNA complex B
To Be Published
- Trnailegau (25 kDa, RNA from Escherichia coli)
- Cysteine synthase a (34 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- Cysk in complex with cdia-ct and trna. (110 kDa, Complex from Escherichia coli 536)
- Trna nuclease cdia (25 kDa, Protein from Escherichia coli 536)
Cryo-EM structure of uropathogenic Escherichia coli 2:1 CysK:CdiA complex
To Be Published
- Cdia-ct (Protein from Escherichia coli 536)
- 2 cysk in complex with 1 cdia-ct. (90 kDa, Complex from Escherichia coli 536)
- Cysk (Protein from Escherichia coli)
Cryo-EM structure of uropathogenic Escherichia coli 2:2 CysK:CdiA complex
To Be Published
- Cdia-ct (Protein from Escherichia coli 536)
- 2 cysk in complex with 2 cdia-ct. (120 kDa, Complex from Escherichia coli 536)
- Cysk (Protein from Escherichia coli)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8k60
Q-score: 0.447
Shi J, Ye Z, Feng Z, Wen A, Wang L, Zhang Z, Xu L, Song Q, Wang F, Liu T, Wang S, Feng Y, Lin W
iScience (2024) 27 pp. 110421-110421 [ Pubmed: 39108719 DOI: doi:10.1016/j.isci.2024.110421 ]
- Dna-directed rna polymerase subunit alpha (36 kDa, Protein from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
- Template strand dna for afss promoter (18 kDa, DNA from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
- Dna-directed rna polymerase subunit beta (128 kDa, Protein from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
- Streptomyces coelicolor transcription initiation complex with the global transcription factor afsr (Complex from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
- Magnesium ion (24 Da, Ligand)
- Regulatory protein afsr (105 kDa, Protein from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
- Non-template strand dna for afss promoter (18 kDa, DNA from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
- Rna polymerase principal sigma factor hrdb (56 kDa, Protein from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
- Dna-directed rna polymerase subunit beta' (144 kDa, Protein from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase subunit omega (9 kDa, Protein from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145))
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with bedaquiline(BDQ)
Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 8j0s
Q-score: 0.592
Zhang Y, Lai Y, Zhou S, Ran T, Zhang Y, Zhao Z, Feng Z, Yu L, Xu J, Shi K, Wang J, Pang Y, Li L, Chen H, Guddat LW, Gao Y, Liu F, Rao Z, Gong H
Nature (2024) 631 pp. 409-414 [ DOI: doi:10.1038/s41586-024-07605-8 Pubmed: 38961288 ]
- Atp synthase epsilon chain (13 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit b (18 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit c (8 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase gamma chain (33 kDa, Protein from Mycobacterium tuberculosis)
- Bedaquiline (555 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Mycobacterium tuberculosis atp synthase in complex with bedaquiline(bdq) (Complex from Mycobacterium tuberculosis)
- Magnesium ion (24 Da, Ligand)
- Atp synthase subunit beta (53 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp synthase subunit a (27 kDa, Protein from Mycobacterium tuberculosis)
- Multifunctional fusion protein (48 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit alpha (59 kDa, Protein from Mycobacterium tuberculosis)
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in the apo-form
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8j0t
Q-score: 0.543
Zhang Y, Lai Y, Zhou S, Ran T, Zhang Y, Zhao Z, Feng Z, Yu L, Xu J, Shi K, Wang J, Pang Y, Li L, Chen H, Guddat LW, Gao Y, Liu F, Rao Z, Gong H
Nature (2024) 631 pp. 409-414 [ DOI: doi:10.1038/s41586-024-07605-8 Pubmed: 38961288 ]
- Atp synthase epsilon chain (13 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit b (18 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit c (8 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase gamma chain (33 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Atp synthase subunit beta (53 kDa, Protein from Mycobacterium tuberculosis)
- Mycobacterium tuberculosis atp synthase (Complex from Mycobacterium tuberculosis)
- Atp synthase subunit a (27 kDa, Protein from Mycobacterium tuberculosis)
- Multifunctional fusion protein (48 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit alpha (59 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
nhTMEM16 R432A mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8tpo
Q-score: 0.467
Feng Z, Alvarenga OE, Accardi A
Nat Struct Mol Biol (2024) 31 pp. 1468-1481 [ Pubmed: 38684930 DOI: doi:10.1038/s41594-024-01284-9 ]
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)
- Lipid scramblase nhtmem16 (83 kDa, Protein from Fusarium vanettenii)
- Calcium ion (40 Da, Ligand)
- Dimeric lipid scramblase nhtmem16 (Complex from Fusarium vanettenii)
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8toi
Q-score: 0.534
Feng Z, Alvarenga OE, Accardi A
Nat Struct Mol Biol (2024) 31 pp. 1468-1481 [ Pubmed: 38684930 DOI: doi:10.1038/s41594-024-01284-9 ]
- Dimeric lipid scramblase nhtmem16 (Complex from Fusarium vanettenii 77-13-4)
- Lipid scramblase nhtmem16 (83 kDa, Protein from Fusarium vanettenii 77-13-4)
- Calcium ion (40 Da, Ligand)
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)